GlyConnect

Taxonomy (1) Protein (1) Source (2) Structure (0) Composition (23) Disease (2) Site (8) Peptide (8)

Taxonomy

Homo sapiens (Human)

Protein

Angiotensin-converting enzyme / Homo sapiens P12821

Source

Mammary Gland (UBERON_0001911)
Blood Serum (UBERON_0001977)

Reported structure

Composition

Disease

Cancer, breast (DOID:1612)
Prostate cancer (DOID:10283)

Reported glycosite

Angiotensin-converting enzyme / Homo sapiens :
- Asn-141
- Asn-445
- Asn-509
- Asn-523
- Asn-690
- Asn-710
- Asn-714
- Asn-1225

Mass spectrometry validated peptide

- Hex:6 HexNAc:6 NeuAc:3 (avg mass : 3083.8134 )
- Hex:6 HexNAc:6 NeuAc:2 (avg mass : 2792.5555 )
- Hex:6 HexNAc:3 (avg mass : 1600.4547 )
- Hex:6 HexNAc:5 NeuAc:2 (avg mass : 2589.3605 )
- Hex:5 HexNAc:4 dHex:2 NeuAc:2 (avg mass : 2516.3091 )
- Hex:6 HexNAc:6 dHex:2 NeuAc:2
- Hex:6 HexNAc:5 dHex:1 NeuAc:2 (avg mass : 2735.5035 )
- Hex:9 HexNAc:2 (avg mass : 1883.6869 )
- Hex:6 HexNAc:6 dHex:4 NeuAc:3
- Hex:6 HexNAc:6 dHex:1 NeuAc:3 (avg mass : 3229.9564 )
- Hex:7 HexNAc:6 dHex:2 NeuAc:1
- Hex:8 HexNAc:2 (avg mass : 1721.5445 )
- Hex:6 HexNAc:6 dHex:2 NeuAc:3
- Hex:6 HexNAc:4 dHex:1 NeuAc:1 (avg mass : 2241.0506 )
- Hex:6 HexNAc:4 dHex:2 (avg mass : 2095.9357 )
- Hex:5 HexNAc:4 NeuAc:1 (avg mass : 1932.7652 )
- Hex:6 HexNAc:5 NeuAc:1 (avg mass : 2298.1026 )
- Hex:7 HexNAc:6 NeuAc:2 (avg mass : 2954.6979 )
- Hex:6 HexNAc:6 dHex:3 NeuAc:3 (avg mass : 3522.2424 )
- Hex:5 HexNAc:4 dHex:1 NeuAc:2 (avg mass : 2370.1661 )
- Hex:6 HexNAc:4 NeuAc:1 (avg mass : 2094.9076 )
- Hex:6 HexNAc:6 dHex:1 NeuAc:2 (avg mass : 2938.6985 )
- Hex:5 HexNAc:4 NeuAc:2 (avg mass : 2224.0231 )

Protein and gene references

UniProtKB : P12821

neXtProt : NX_P12821

GeneCards : ACE

3D structure from PDB

Select a PDB entry

Github Wiki

3D visualization by LiteMol

References (2)

Large-scale intact glycopeptide identification by Mascot database search (2018)
Ravi Chand Bollineni, Christian Jeffrey Koehler, Randi Elin Gislefoss, Jan Haug Anonsen, Bernd Thiede
Pubmed : 29391424 DOI : 10.1038/s41598-018-20331-2
Status : Unreviewed

Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018)
Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang
Pubmed : 29741879 DOI : 10.1021/acs.analchem.8b01137
Status : Unreviewed