IEETTMTTQTPAPIQAPSAILPLPGQSVER (30aa)

Taxonomy

• Homo sapiens (Human)

Protein

• Inter-alpha-trypsin inhibitor heavy chain h4 / Homo sapiens    Q14624

Source

• Blood Serum (UBERON_0001977)  
• Urine (UBERON_0001088)  

Reported structure

Composition

• Hex:1 HexNAc:1 NeuAc:1 (avg mass : 674.6106 )
• Hex:1 HexNAc:1 NeuAc:1 NeuGc:1 (avg mass : 981.8679 )
• Hex:1 HexNAc:1 NeuAc:2 (avg mass : 965.8685 )
• Hex:2 HexNAc:2 NeuAc:1 (avg mass : 1039.948 )
• Hex:2 HexNAc:2 NeuAc:2 (avg mass : 1331.2059 )
• Hex:2 HexNAc:2 dHex:2 NeuAc:1 (avg mass : 1332.234 )
• Hex:3 HexNAc:2 dHex:1 (avg mass : 1056.9755 )
• Hex:3 HexNAc:3 NeuAc:2 (avg mass : 1696.5433 )
• Hex:4 HexNAc:6 (avg mass : 1885.7549 )

Disease

• Prostate cancer (DOID:10283)

Reference

• Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis (2021 - Rebeca Kawahara, Anastasia Chernykh, Kathirvel Alagesan, Marshall Bern, Weiqian Cao, Robert J. Chalkley, Kai Cheng, Matthew S. Choo, Nathan Edwards, Radoslav Goldman, Marcus Hoffmann, Yingwei Hu, Yifan Huang, Jin Young Kim, Doron Kletter, Benoit Liquet, Mingqi Liu, Yehia Mechref, Bo Meng, Sriram Neelamegham, Terry Nguyen-Khuong, Jonas Nilsson, Adam Pap, Gun Wook Park, Benjamin L. Parker, Cassandra L. Pegg, Josef M. Penninger, Toan K. Phung, Markus Pioch, Erdmann Rapp, Enes Sakalli, Miloslav Sanda, Benjamin L. Schulz, Nichollas E. Scott, Georgy Sofronov, Johannes Stadlmann, Sergey Y. Vakhrushev, Christina M. Woo, Hung-Yi Wu, Pengyuan Yang, Wantao Ying, Hui Zhang, Yong Zhang, Jingfu Zhao, Joseph Zaia, Stuart M. Haslam, Giuseppe Palmisano, Jong Shin Yoo, Göran Larson, Kai-Hooi Khoo, Katalin F. Medzihradszky, Daniel Kolarich, Nicolle H. Packer, Morten Thaysen-Andersen) / Status : Reviewed
• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed

Reported glycosite

• Inter-alpha-trypsin inhibitor heavy chain h4 / Homo sapiens
  •        Thr-725
  •        Ser-733

Mass spectrometry observed peptide

• IEETTMTTQTPAPIQAPSAILPLPGQSVER (30aa)
  •    Q14624    Ser-733     Inter-alpha-trypsin inhibitor heavy chain h4 / Homo sapiens
  •    Q14624    Thr-725     Inter-alpha-trypsin inhibitor heavy chain h4 / Homo sapiens