GlyConnect

Taxonomy (1) Protein (1) Source (2) Structure (0) Composition (5) Disease (2) Site (2) Peptide (1)

Taxonomy

Homo sapiens (Human)

Protein

Progranulin / Homo sapiens P28799

Source

Mammary Gland (UBERON_0001911)
Urine (UBERON_0001088)

Reported structure

Composition

Disease

Prostate cancer (DOID:10283)
Cancer, breast (DOID:1612)

Reported glycosite

Progranulin / Homo sapiens :
- Asn-530
- Thr-532

Mass spectrometry validated peptide

DVECGEGHFCHDNQTCCR (18aa)
- P28799 Thr-532
DVECGEGHFCHDNQTCCR (18aa)
- P28799 Asn-530

- Hex:3 HexNAc:2 (avg mass : 910.8325 )
- Hex:3 HexNAc:2 (avg mass : 910.8325 )
- Hex:2 HexNAc:2 (avg mass : 748.6901 )
- Hex:9 HexNAc:2 (avg mass : 1883.6869 )
- Hex:2 HexNAc:2 (avg mass : 748.6901 )
- Hex:2 HexNAc:2 dHex:1 (avg mass : 894.8331 )
- Hex:2 HexNAc:2 dHex:1 (avg mass : 894.8331 )
- Hex:8 HexNAc:2 (avg mass : 1721.5445 )

References (2)

Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018)
Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang
Pubmed : 29741879 DOI : 10.1021/acs.analchem.8b01137
Status : Unreviewed

Distinct urinary glycoprotein signatures in prostate cancer patients (2018)
Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano
Pubmed : 30237853 DOI : 10.18632/oncotarget.26005
Status : Unreviewed