Esophageal cancer

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-acid glycoprotein 1 / Homo sapiens    P02763
• Alpha-1-antichymotrypsin / Homo sapiens    P01011
• Alpha-1-antitrypsin / Homo sapiens    P01009
• Alpha-1b-glycoprotein / Homo sapiens    P04217
• Alpha-2-macroglobulin / Homo sapiens    P01023
• Antithrombin-III / Homo sapiens    P01008
• Beta-2-glycoprotein 1 / Homo sapiens    P02749
• Ceruloplasmin / Homo sapiens    P00450
• Clusterin / Homo sapiens    P10909
• Complement c1r subcomponent / Homo sapiens    P00736
• Complement c3 / Homo sapiens    P01024
• Complement component c6 / Homo sapiens    P13671
• Complement factor h / Homo sapiens    P08603
• Corticosteroid-binding globulin / Homo sapiens    P08185
• Fibronectin / Homo sapiens    P02751
• Haptoglobin / Homo sapiens    P00738
• Hemopexin / Homo sapiens    P02790
• Heparin cofactor 2 / Homo sapiens    P05546
• Histidine-rich glycoprotein / Homo sapiens    P04196
• Inter-alpha-trypsin inhibitor heavy chain h1 / Homo sapiens    P19827
• Inter-alpha-trypsin inhibitor heavy chain h4 / Homo sapiens    Q14624
• Kininogen-1 / Homo sapiens    P01042
• Leucine-rich alpha-2-glycoprotein / Homo sapiens    P02750
• N-acetylmuramoyl-l-alanine amidase / Homo sapiens    Q96PD5
• Pigment epithelium-derived factor / Homo sapiens    P36955
• Plasma kallikrein / Homo sapiens    P03952
• Plasma protease c1 inhibitor / Homo sapiens    P05155
• Prothrombin / Homo sapiens    P00734
• Serum paraoxonase/arylesterase 1 / Homo sapiens    P27169
• Vitronectin / Homo sapiens    P04004

Source

• Blood Plasma (UBERON_0001969)  

Reported structure

• N-Linked / Complex / Structure 2643
• N-Linked / Complex / Structure 231
• N-Linked / Complex / Structure 3507
• N-Linked / Complex / Structure 1523
• N-Linked / Complex / Structure 473
• N-Linked / Complex / NeuAc(?2-?)Gal(?1-?)GlcNAc(?1-?)Man(a1-3)[NeuAc(?2-?)Gal(?1-?)GlcNAc(?1-?)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / Complex / Structure 572
• N-Linked / Complex / Structure 1519
• N-Linked / Complex / Structure 2391
• N-Linked / Complex / Structure 2575
• N-Linked / Complex / Structure 3629
• N-Linked / Complex / Structure 3185
• N-Linked / Complex / Structure 284
• N-Linked / High-Mannose / Structure 2812
• N-Linked / High-Mannose / Structure 3485
• N-Linked / High-Mannose / Structure 3542
• N-Linked / Hybrid / Structure 2063
• N-Linked / Hybrid / Structure 3469

Composition

• Hex:3 HexNAc:4 dHex:1 (avg mass : 1463.3655 )
• Hex:4 HexNAc:4 NeuAc:1 (avg mass : 1770.6228 )
• Hex:5 HexNAc:2 (avg mass : 1235.1173 )
• Hex:5 HexNAc:3 NeuAc:1 (avg mass : 1729.5702 )
• Hex:5 HexNAc:4 NeuAc:1 (avg mass : 1932.7652 )
• Hex:5 HexNAc:4 NeuAc:2 (avg mass : 2224.0231 )
• Hex:5 HexNAc:4 dHex:1 NeuAc:1 (avg mass : 2078.9082 )
• Hex:5 HexNAc:4 dHex:1 NeuAc:2 (avg mass : 2370.1661 )
• Hex:6 HexNAc:2 (avg mass : 1397.2597 )
• Hex:6 HexNAc:3 NeuAc:1 (avg mass : 1891.7126 )
• Hex:6 HexNAc:5 NeuAc:2 (avg mass : 2589.3605 )
• Hex:6 HexNAc:5 NeuAc:3 (avg mass : 2880.6184 )
• Hex:6 HexNAc:5 dHex:1 NeuAc:2 (avg mass : 2735.5035 )
• Hex:6 HexNAc:5 dHex:1 NeuAc:3 (avg mass : 3026.7614 )
• Hex:6 HexNAc:5 dHex:2 NeuAc:3 (avg mass : 3172.9044 )
• Hex:7 HexNAc:2 (avg mass : 1559.4021 )

Disease

• Esophageal cancer (DOID:5041)

Reference

• Computational framework for identification of intact glycopeptides in complex samples (2014 - Mayampurath A, Yu CY, Song E, Balan J, Mechref Y, Tang H.) / Status : Reviewed

Reported glycosite

• Alpha-1-acid glycoprotein 1 / Homo sapiens
  •        Asn-72
• Alpha-1-antichymotrypsin / Homo sapiens
  •        Asn-106
• Alpha-1-antitrypsin / Homo sapiens
  •        Asn-271
• Alpha-1b-glycoprotein / Homo sapiens
  •        Asn-179
  •        Asn-371
• Alpha-2-macroglobulin / Homo sapiens
  •        Asn-869
  •        Asn-1424
• Antithrombin-III / Homo sapiens
  •        Asn-128
  •        Asn-187
• Beta-2-glycoprotein 1 / Homo sapiens
  •        Asn-253
• Ceruloplasmin / Homo sapiens
  •        Asn-138
  •        Asn-358
  •        Asn-397
  •        Asn-762
• Clusterin / Homo sapiens
  •        Asn-374
• Complement c1r subcomponent / Homo sapiens
  •        Asn-514
• Complement c3 / Homo sapiens
  •        Asn-85
• Complement component c6 / Homo sapiens
  •        Asn-324
• Complement factor h / Homo sapiens
  •        Asn-882
  •        Asn-911
  •        Asn-1029
• Corticosteroid-binding globulin / Homo sapiens
  •        Asn-96
• Fibronectin / Homo sapiens
  •        Asn-528
  •        Asn-1007
• Haptoglobin / Homo sapiens
  •        Asn-184
  •        Asn-241
• Hemopexin / Homo sapiens
  •        Asn-187
  •        Asn-453
• Heparin cofactor 2 / Homo sapiens
  •        Asn-49
  •        Asn-188
• Histidine-rich glycoprotein / Homo sapiens
  •        Asn-125
• Inter-alpha-trypsin inhibitor heavy chain h1 / Homo sapiens
  •        Asn-285
• Inter-alpha-trypsin inhibitor heavy chain h4 / Homo sapiens
  •        Asn-517
• Kininogen-1 / Homo sapiens
  •        Asn-294
• Leucine-rich alpha-2-glycoprotein / Homo sapiens
  •        Asn-186
• N-acetylmuramoyl-l-alanine amidase / Homo sapiens
  •        Asn-367
  •        Asn-485
• Pigment epithelium-derived factor / Homo sapiens
  •        Asn-285
• Plasma kallikrein / Homo sapiens
  •        Asn-127
  •        Asn-396
• Plasma protease c1 inhibitor / Homo sapiens
  •        Asn-238
• Prothrombin / Homo sapiens
  •        Asn-143
  •        Asn-416
• Serum paraoxonase/arylesterase 1 / Homo sapiens
  •        Asn-253
  •        Asn-324
• Vitronectin / Homo sapiens
  •        Asn-169
  •        Asn-242

Mass spectrometry observed peptide