Lysosomal storage disease

Taxonomy

• Homo sapiens (Human)

Protein

• Urine glycopeptide / Homo sapiens    

Source

• Urine (UBERON_0001088)  

Reported structure

• O-Linked / Core 1 / NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc
• O-Linked / Core 2 / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-3)]GalNAc

Composition

• Hex:1 HexNAc:1 NeuAc:2 (avg mass : 965.8685 )
• Hex:2 HexNAc:2 NeuAc:2 (avg mass : 1331.2059 )

Disease

• Lysosomal storage disease (DOID:3211)

Reference

• Isolation and structural characterization of sialic-acid-containing glycopeptides of the O-glycosidic type from the urine of two patients with an hereditary deficiency in alpha-N-acetylgalactosaminidase activity. (1989 - Linden H, Klein R, Egge H, Peter-Katalinic J, Dabrowski J, Schindler D) / Status : Reviewed

Reported glycosite

• Urine glycopeptide / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide