Sialidosis (Mucolipidosis I)

Taxonomy

• Homo sapiens (Human)

Protein

• Uncharacterized protein from Urine / Homo sapiens    

Source

• Urine (UBERON_0001088)  

Reported structure

• O-Linked / Core 1 / NeuAc(a2-3)Gal(b1-3)GalNAc
• O-Linked / Core 1 / NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc
• O-Linked / Core 2 / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-3)]GalNAc

Composition

• Hex:1 HexNAc:1 NeuAc:1 (avg mass : 674.6106 )
• Hex:1 HexNAc:1 NeuAc:2 (avg mass : 965.8685 )
• Hex:2 HexNAc:2 NeuAc:2 (avg mass : 1331.2059 )

Disease

• Sialidosis (Mucolipidosis I) (DOID:3343)

Reference

• Structural analysis of O-glycosidic type of sialyloligosaccharide-alditols derived from urinary glycopeptides of a sialidosis patient. (1988 - van Pelt J, Van Bilsen D, Kamerling J, Vliegenthart J) / Status : Reviewed
• The structure of sialyl-glycopeptides of the O-glycosidic type, isolated from sialidosis (mucolipidosis I) urine. (1984 - Lecat D, Lemonnier M, Derappe C, Lhermitte M, van Halbeek H, Dorland L, Vliegenthart J) / Status : Reviewed

Reported glycosite

• Uncharacterized protein from Urine / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide