Familial hepatic adenoma

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-acid glycoprotein 1 / Homo sapiens    P02763
• Alpha-1-antitrypsin / Homo sapiens    P01009
• Serotransferrin / Homo sapiens    P02787

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 10738
• N-Linked / Complex / Structure 10804
• N-Linked / Complex / Structure 10712
• N-Linked / Complex / Structure 10735
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ NeuAc"
• N-Linked / Complex / Structure 10835
• N-Linked / Complex / Structure 10692
• N-Linked / Complex / Structure 10742
• N-Linked / Complex / Structure 10728
• N-Linked / Complex / Structure 10794
• N-Linked / Complex / Structure 10795
• N-Linked / Complex / Structure 10700
• N-Linked / Complex / Structure 10694
• N-Linked / Complex / Structure 10705
• N-Linked / Complex / Structure 10706
• N-Linked / Complex / Structure 10720
• N-Linked / Complex / Structure 10721
• N-Linked / Complex / Structure 10786
• N-Linked / Complex / Structure 10725
• N-Linked / Complex / Structure 10785
• N-Linked / Complex / Structure 10693
• N-Linked / Complex / Structure 10737
• N-Linked / Complex / Structure 10761
• N-Linked / Complex / Structure 10752
• N-Linked / Complex / Structure 10799
• N-Linked / Complex / Structure 10791
• N-Linked / Complex / Structure 10748
• N-Linked / Complex / Structure 10805
• N-Linked / Complex / Structure 10708
• N-Linked / Complex / Structure 10734
• N-Linked / Complex / Structure 10750
• N-Linked / Complex / Structure 10775
• N-Linked / Complex / Structure 10803
• N-Linked / Complex / Structure 10792
• N-Linked / Complex / Structure 10774
• N-Linked / Complex / Structure 10689
• N-Linked / Complex / Structure 10751
• N-Linked / Complex / Structure 10718
• N-Linked / Complex / Structure 10701
• N-Linked / Complex / Structure 10770
• N-Linked / Complex / Structure 10719
• N-Linked / Complex / Structure 10707
• N-Linked / Complex / Structure 10807
• N-Linked / Complex / Structure 10821
• N-Linked / Complex / Structure 10753
• N-Linked / Complex / Structure 10818
• N-Linked / High-Mannose / Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-3)]Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / High-Mannose / Structure 3485

Composition

• Hex:3 HexNAc:4 dHex:1 (avg mass : 1463.3655 )
• Hex:4 HexNAc:4 dHex:1 (avg mass : 1625.5079 )
• Hex:5 HexNAc:2 (avg mass : 1235.1173 )
• Hex:5 HexNAc:4 (avg mass : 1641.5073 )
• Hex:5 HexNAc:4 NeuAc:1 (avg mass : 1932.7652 )
• Hex:5 HexNAc:4 NeuAc:2 (avg mass : 2224.0231 )
• Hex:5 HexNAc:4 NeuAc:3 (avg mass : 2515.281 )
• Hex:5 HexNAc:4 NeuAc:4 (avg mass : 2806.5389 )
• Hex:5 HexNAc:4 dHex:1 (avg mass : 1787.6503 )
• Hex:5 HexNAc:4 dHex:1 NeuAc:1 (avg mass : 2078.9082 )
• Hex:5 HexNAc:4 dHex:1 NeuAc:2 (avg mass : 2370.1661 )
• Hex:5 HexNAc:4 dHex:1 NeuAc:3 (avg mass : 2661.424 )
• Hex:5 HexNAc:5 dHex:1 NeuAc:2 (avg mass : 2573.3611 )
• Hex:6 HexNAc:2 (avg mass : 1397.2597 )
• Hex:6 HexNAc:5 NeuAc:1 (avg mass : 2298.1026 )
• Hex:6 HexNAc:5 NeuAc:2 (avg mass : 2589.3605 )
• Hex:6 HexNAc:5 NeuAc:3 (avg mass : 2880.6184 )
• Hex:6 HexNAc:5 NeuAc:4 (avg mass : 3171.8763 )
• Hex:6 HexNAc:5 NeuAc:5 (avg mass : 3463.1342 )
• Hex:6 HexNAc:5 dHex:1 NeuAc:2 (avg mass : 2735.5035 )
• Hex:6 HexNAc:5 dHex:1 NeuAc:3 (avg mass : 3026.7614 )
• Hex:6 HexNAc:5 dHex:1 NeuAc:4 (avg mass : 3318.0193 )
• Hex:7 HexNAc:6 NeuAc:1 (avg mass : 2663.44 )
• Hex:7 HexNAc:6 NeuAc:2 (avg mass : 2954.6979 )
• Hex:7 HexNAc:6 NeuAc:3 (avg mass : 3245.9558 )
• Hex:7 HexNAc:6 NeuAc:4 (avg mass : 3537.2137 )
• Hex:7 HexNAc:6 NeuAc:5 (avg mass : 3828.4716 )
• Hex:7 HexNAc:6 NeuAc:6 (avg mass : 4119.7295 )
• Hex:7 HexNAc:6 dHex:1 NeuAc:3 (avg mass : 3392.0988 )
• Hex:7 HexNAc:6 dHex:1 NeuAc:4 (avg mass : 3683.3567 )
• Hex:7 HexNAc:6 dHex:2 NeuAc:4 (avg mass : 3829.4997 )
• Hex:8 HexNAc:7 NeuAc:3 (avg mass : 3611.2932 )
• Hex:8 HexNAc:7 NeuAc:4 (avg mass : 3902.5511 )
• Hex:8 HexNAc:7 dHex:1 NeuAc:4 (avg mass : 4048.6941 )
• Hex:9 HexNAc:8 NeuAc:4 (avg mass : 4267.8885 )
• Hex:9 HexNAc:8 NeuAc:5 (avg mass : 4559.1464 )

Disease

• Familial hepatic adenoma (DOID:111366)

Reference

• Aberrant sialylation in a patient with a HNF1α variant and liver adenomatosis (2021 - Luisa Sturiale, Marie-Cécile Nassogne, Angelo Palmigiano, Angela Messina, Immacolata Speciale, Rosangela Artuso, Gaetano Bertino, Nicole Revencu, Xavier Stephénne, Cristina De Castro, Gert Matthijs, Rita Barone, Jaak Jaeken, Domenico Garozzo) / Status : Reviewed

Reported glycosite

• Alpha-1-acid glycoprotein 1 / Homo sapiens
  •        Undefined site
• Alpha-1-antitrypsin / Homo sapiens
  •        Undefined site
• Serotransferrin / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide