Hex:6 HexNAc:5 dHex:2

Taxonomy

• Homo sapiens (Human)
• Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)

Protein

• 4F2 cell-surface antigen heavy chain / Homo sapiens    P08195
• Agrin / Homo sapiens    O00468
• Alpha-2-HS-glycoprotein / Homo sapiens    P02765
• Biglycan / Homo sapiens    P21810
• Cation-dependent mannose-6-phosphate receptor / Homo sapiens    P20645
• CD109 antigen / Homo sapiens    Q6YHK3
• CD166 antigen / Homo sapiens    Q13740
• CD44 antigen / Homo sapiens    P16070
• Clusterin / Homo sapiens    P10909
• Collagen alpha-2(VI) chain / Homo sapiens    P12110
• Complement factor h / Homo sapiens    P08603
• Dipeptidyl peptidase 1 / Homo sapiens    P53634
• Disintegrin and metalloproteinase domain-containing protein 17 / Homo sapiens    P78536
• Endothelin-converting enzyme 1 / Homo sapiens    P42892
• Epidermal growth factor receptor / Homo sapiens    P00533
• Erythropoietin / Homo sapiens    P01588
• Fibromodulin / Homo sapiens    Q06828
• Fibronectin / Homo sapiens    P02751
• Folate receptor alpha / Homo sapiens    P15328
• Gamma-glutamyltransferase light chain 1 / Homo sapiens    Q9BX51
• Gamma-glutamyltransferase light chain 2 / Homo sapiens    Q14390
• Gamma-glutamyltranspeptidase 1 / Homo sapiens    P19440
• Golgi membrane protein 1 / Homo sapiens    Q8NBJ4
• Haptoglobin / Homo sapiens    P00738
• Hemopexin / Homo sapiens    P02790
• Immunoglobulin heavy constant alpha 2 / Homo sapiens    P01877
• Immunoglobulin heavy constant mu / Homo sapiens    P01871
• Integrin beta-1 / Homo sapiens    P05556
• Interleukin-1 receptor accessory protein / Homo sapiens    Q9NPH3
• Kininogen-1 / Homo sapiens    P01042
• L-selectin / Homo sapiens    P14151
• Lactotransferrin / Homo sapiens    P02788
• Leucine-rich alpha-2-glycoprotein / Homo sapiens    P02750
• Lysosome-associated membrane glycoprotein 1 / Homo sapiens    P11279
• Lysosome-associated membrane glycoprotein 2 / Homo sapiens    P13473
• Macrosialin / Homo sapiens    P34810
• Membrane primary amine oxidase / Homo sapiens    Q16853
• Olfactomedin-like protein 3 / Homo sapiens    Q9NRN5
• Prolactin-inducible protein / Homo sapiens    P12273
• Prolow-density lipoprotein receptor-related protein 1 / Homo sapiens    Q07954
• Prostaglandin F2 receptor negative regulator / Homo sapiens    Q9P2B2
• Prostaglandin-h2 d-isomerase / Homo sapiens    P41222
• Protein AMBP / Homo sapiens    P02760
• Prothrombin / Homo sapiens    P00734
• Receptor tyrosine-protein kinase erbB-2 / Homo sapiens    P04626
• Receptor-type tyrosine-protein phosphatase C / Homo sapiens    P08575
• Translocon-associated protein subunit alpha / Homo sapiens    P43307
• Transmembrane protein 87A / Homo sapiens    Q8NBN3
• Tubulointerstitial nephritis antigen-like / Homo sapiens    Q9GZM7
• Vitronectin / Homo sapiens    P04004
• Von willebrand factor / Homo sapiens    P04275
• Zinc-alpha-2-glycoprotein / Homo sapiens    P25311
• Recombinant Spike glycoprotein (FreeStyle 293-F) / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)    P0DTC2

Source

• Blood Plasma (UBERON_0001969)  
• Blood Serum (UBERON_0001977)  
• Kidney (UBERON_0002113)   BHK-21 (CVCL_1914)  
• Mammalian Vulva (UBERON_0000997)   A-431 (CVCL_0037)  
• Mammary Gland (UBERON_0001911)  
• Milk (UBERON_0001913)  
• Urine (UBERON_0001088)  
• FreeStyle 293-F (CVCL_D603)  
• RPMI-1788 (CVCL_2710)   B-Lymphocyte (CL_0000236)  
• Fibroblast (CL_0000057)  
• Leukocyte (CL_0000738)  

Reported structure

• N-Linked / Complex / Fuc(a1-2)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[Gal(b1-4)GlcNAc(b1-2)[Gal(b1-4)GlcNAc(b1-6)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Fuc(a1-2)Gal(b1-4)GlcNAc(b1-?)[Gal(b1-4)GlcNAc(b1-?)]Man(a1-6)[Gal(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[Gal(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-4)[Gal(b1-4)GlcNAc(b1-2)]Man(a1-?)[Gal(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Gal(?1-?)GlcNAc(?1-?)[Gal(?1-?)GlcNAc(?1-?)]Man(a1-?)[Gal(?1-?)GlcNAc(?1-?)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(?1-6)]GlcNAc+"+ Fuc"
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-2)[Gal(b1-4)GlcNAc(b1-4)]Man(a1-3)[Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"+ Fuc(a1-2)"
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-2)[Gal(b1-4)GlcNAc(b1-4)]Man(a1-3)[Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"+ Fuc(a1-3)"
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Structure 3232

Composition

• Hex:6 HexNAc:5 dHex:2 (avg mass : 2299.1307 )

Disease

• Cancer, breast (DOID:1612)
• Carcinoma (DOID:305)
• Carcinoma, Hepatocellular (DOID:684)
• Carcinoma, Squamous cell (DOID:1749)
• COVID-19 (DOID:0080600)
• Cystic Fibrosis (DOID:1485)
• Prostate cancer (DOID:10283)

Reference

• Site-specific glycan analysis of the SARS-CoV-2 spike (2020 - Yasunori Watanabe, Joel D. Allen, Daniel Wrapp, Jason S. McLellan, Max Crispin) / Status : Unreviewed
• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed
• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• Protein and Site Specificity of Fucosylation in Liver-Secreted Glycoproteins (2014 - Pompach P, Ashline DJ, Brnakova Z, Benicky J, Sanda M, Goldman R.) / Status : Reviewed
• N-glycosylation potential of maize: the human lactoferrin used as a model. (2001 - Samyn-Petit B, Gruber V, Flahaut C, Wajda-Dubos JP, Farrer S, Pons A, Desmaizieres G, Slomianny MC, Theisen M, Delannoy P) / Status : Reviewed
• Carbohydrate structures of soluble human L-selectin recombinantly expressed in baby-hamster kidney cells. (2000 - Gohlke M, Mach U, Nuck R, Zimmermann-Kordmann M, Grunow D, Fieger C, Volz B, Tauber R, Petri T, Debus N, Reutter W) / Status : Reviewed
• Unusual N-glycosylation of a recombinant human erythropoietin expressed in a human lymphoblastoid cell line does not alter its biological properties. (2000 - Cointe D, Bliard R, Jorieux S, Leroy Y, Glacet A, Verbert A, Bourel D, Chirat F) / Status : Reviewed
• Characterization of the carbohydrate chains of the secreted form of the human epidermal growth factor receptor. (2000 - Stroop C, Weber W, Gerwig G, Nimtz M, Kamerling J, Vliegenthart J) / Status : Reviewed
• Structural study of the sugar chains of human leukocyte common antigen CD45. (1993 - Sato T, Furukawa K, Autero M, Gahmberg C, Kobata A) / Status : Reviewed
• Structures of the asparagine-linked oligosaccharide chains of human von Willebrand factor. Occurrence of blood group A, B, and H(O) structures. (1992 - Matsui T, Titani K, Mizuochi T) / Status : Reviewed
• Additional fucosyl residues on membrane glycoproteins but not a secreted glycoprotein from cystic fibrosis fibroblasts. (1990 - Wang YM, Hare TR, Won B, Stowell CP, Scanlin TF, Glick MC, Hård K, van Kuik JA, Vliegenthart JF) / Status : Reviewed
• Structural study of the sugar chains of human lactoferrin: finding of four novel complex-type asparagine-linked sugar chains. (1982 - Matsumoto A, Yoshima H, Takasaki S, Kobata A) / Status : Reviewed

Reported glycosite

• 4F2 cell-surface antigen heavy chain / Homo sapiens
  •        Asn-381
• Agrin / Homo sapiens
  •        Asn-250
• Alpha-2-HS-glycoprotein / Homo sapiens
  •        Asn-156
• Biglycan / Homo sapiens
  •        Asn-270
  •        Asn-311
• Cation-dependent mannose-6-phosphate receptor / Homo sapiens
  •        Asn-83
• CD109 antigen / Homo sapiens
  •        Asn-118
• CD166 antigen / Homo sapiens
  •        Asn-306
  •        Asn-480
• CD44 antigen / Homo sapiens
  •        Asn-57
• Clusterin / Homo sapiens
  •        Asn-374
• Collagen alpha-2(VI) chain / Homo sapiens
  •        Asn-785
• Complement factor h / Homo sapiens
  •        Asn-882
  •        Asn-911
• Dipeptidyl peptidase 1 / Homo sapiens
  •        Asn-276
• Disintegrin and metalloproteinase domain-containing protein 17 / Homo sapiens
  •        Asn-539
• Endothelin-converting enzyme 1 / Homo sapiens
  •        Asn-539
• Epidermal growth factor receptor / Homo sapiens
  •        Undefined site
• Erythropoietin / Homo sapiens
  •        Asn-65
• Fibromodulin / Homo sapiens
  •        Asn-166
• Fibronectin / Homo sapiens
  •        Undefined site
  •        Asn-528
• Folate receptor alpha / Homo sapiens
  •        Asn-161
• Gamma-glutamyltransferase light chain 1 / Homo sapiens
  •        Asn-167
• Gamma-glutamyltransferase light chain 2 / Homo sapiens
  •        Asn-160
• Gamma-glutamyltranspeptidase 1 / Homo sapiens
  •        Asn-511
• Golgi membrane protein 1 / Homo sapiens
  •        Asn-109
• Haptoglobin / Homo sapiens
  •        Asn-184
  •        Asn-241
• Hemopexin / Homo sapiens
  •        Asn-64
  •        Asn-187
  •        Asn-453
• Immunoglobulin heavy constant alpha 2 / Homo sapiens
  •        Asn-205
• Immunoglobulin heavy constant mu / Homo sapiens
  •        Asn-209
• Integrin beta-1 / Homo sapiens
  •        Asn-50
• Interleukin-1 receptor accessory protein / Homo sapiens
  •        Asn-118
• Kininogen-1 / Homo sapiens
  •        Asn-169
  •        Asn-294
• L-selectin / Homo sapiens
  •        Undefined site
• Lactotransferrin / Homo sapiens
  •        Undefined site
• Leucine-rich alpha-2-glycoprotein / Homo sapiens
  •        Asn-325
• Lysosome-associated membrane glycoprotein 1 / Homo sapiens
  •        Asn-84
  •        Asn-249
  •        Asn-261
• Lysosome-associated membrane glycoprotein 2 / Homo sapiens
  •        Asn-32
  •        Asn-49
  •        Asn-101
  •        Asn-275
  •        Asn-356
• Macrosialin / Homo sapiens
  •        Asn-199
• Membrane primary amine oxidase / Homo sapiens
  •        Asn-618
• Olfactomedin-like protein 3 / Homo sapiens
  •        Asn-248
• Prolactin-inducible protein / Homo sapiens
  •        Asn-105
• Prolow-density lipoprotein receptor-related protein 1 / Homo sapiens
  •        Asn-3333
• Prostaglandin F2 receptor negative regulator / Homo sapiens
  •        Asn-300
• Prostaglandin-h2 d-isomerase / Homo sapiens
  •        Asn-51
  •        Asn-78
• Protein AMBP / Homo sapiens
  •        Asn-250
• Prothrombin / Homo sapiens
  •        Asn-416
• Receptor tyrosine-protein kinase erbB-2 / Homo sapiens
  •        Asn-530
• Receptor-type tyrosine-protein phosphatase C / Homo sapiens
  •        Undefined site
• Translocon-associated protein subunit alpha / Homo sapiens
  •        Asn-136
• Transmembrane protein 87A / Homo sapiens
  •        Asn-62
• Tubulointerstitial nephritis antigen-like / Homo sapiens
  •        Asn-78
• Vitronectin / Homo sapiens
  •        Asn-169
• Von willebrand factor / Homo sapiens
  •        Undefined site
• Zinc-alpha-2-glycoprotein / Homo sapiens
  •        Asn-128
• Recombinant Spike glycoprotein (FreeStyle 293-F) / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
  •        Asn-331

Mass spectrometry observed peptide

• LELNLTDSENATCLYAK (17aa)
  •    P13473    Asn-32
• WQMNFTVR (8aa)
  •    P13473    Asn-49
• SCGECIQAGPNCGWCTNSTFIQEGMPTSAR (30aa)
  •    P05556    Asn-50
• WFSAGLASNSSWLR (14aa)
  •    P41222    Asn-51
• AFNSTLPTMAQMEK (14aa)
  •    P16070    Asn-57
• NTTIFLK (7aa)
  •    Q8NBN3    Asn-62
• SVVAPATDGGLNLTSTFLR (19aa)
  •    P41222    Asn-78
• ADDCALPYLGAICYCDLFCNR (21aa)
  •    Q9GZM7    Asn-78
• EAGNHTSGAGIVQINK (16aa)
  •    P20645    Asn-83
• SSCGKENTSDPSIVIAFGR (19aa)
  •    P11279    Asn-84
• IAVQFGPGFSWIANFTK (17aa)
  •    P13473    Asn-101
• TFYWDFYTNR (10aa)
  •    P12273    Asn-105
• AVIVNNITTGER (12aa)
  •    Q8NBJ4    Asn-109
• NTTYCSK (7aa)
  •    Q9NPH3    Asn-118
• TQDEIIFSNSTR (12aa)
  •    Q6YHK3    Asn-118
• FGCEIENNR (9aa)
  •    P25311    Asn-128
• FYIQNFTALPLNTVVPPQR (19aa)
  •    P43307    Asn-136
• VCQDCPIIAPINDTR (15aa)
  •    P02765    Asn-156
• IHNQIIPNVTTVER (14aa)
  •    Q9BX51    Asn-167
• IHNQIIPNVTTVER (14aa)
  •    Q14390    Asn-160
• IHNQIIPNVTTVER (14aa)
  •    P19440    Asn-511
• GWNWTSGFNK (10aa)
  •    P15328    Asn-161
• IYIDHNNITR (10aa)
  •    Q06828    Asn-166
• NGSLFAFR (8aa)
  •    P04004    Asn-169
• AWGISVLNPNK (11aa)
  •    P34810    Asn-199
• TPLTANITK (9aa)
  •    P01877    Asn-205
• GITFQQNASSMCVPDQDTAIR (21aa)
  •    P01871    Asn-209
• FHLANR (6aa)
  •    Q9NRN5    Asn-248
• KDNTTVTR (8aa)
  •    P11279    Asn-249
• DPCSNVTCSFGSTCAR (16aa)
  •    O00468    Asn-250
• YFYNGTSMACETFQYGGCMGNGNNFVTEK (29aa)
  •    P02760    Asn-250
• IININPNK (8aa)
  •    P11279    Asn-261
• MIENGSISFIPTIR (14aa)
  •    P21810    Asn-270
• LNSSTIK (7aa)
  •    P13473    Asn-275
• IITNNSQTPIISPQEVVSCSQYAQGCEGGFPYIIAGK (37aa)
  •    P53634    Asn-276
• ELDLTCNITTDR (12aa)
  •    Q9P2B2    Asn-300
• NATGDYK (7aa)
  •    Q13740    Asn-306
• IIQVVYIHSNNITK (14aa)
  •    P21810    Asn-311
• MFSQNDTR (8aa)
  •    P02750    Asn-325
• RFPNIT (6aa)
  •    P0DTC2    Asn-331
• VQPFNVTQGK (10aa)
  •    P13473    Asn-356
• IANITQGEDQYYIR (14aa)
  •    P10909    Asn-374
• IIIAGTNSSDIQQIISIIESNK (22aa)
  •    P08195    Asn-381
• CLLYPPWDKNFTENDLLVR (19aa)
  •    P00734    Asn-416
• NFTENDLLVR (10aa)
  •    P00734    Asn-416
• IIISPEENVTITCTAENQIER (21aa)
  •    Q13740    Asn-480
• DQCIVDDITYNVNDTFHK (18aa)
  •    P02751    Asn-528
• GHCWGPGPTQCVNCSQFLR (19aa)
  •    P04626    Asn-530
• FFNFSWR (7aa)
  •    P42892    Asn-539
• KCQEAINATCK (11aa)
  •    P78536    Asn-539
• CQEAINATCK (10aa)
  •    P78536    Asn-539
• IQMISFAGEPIPQNSSMAR (19aa)
  •    Q16853    Asn-618
• NMTLFSDLVAEK (12aa)
  •    P12110    Asn-785
• TCVSNCTASQFVCK (14aa)
  •    Q07954    Asn-3333