Hex:5 HexNAc:4 dHex:3 NeuAc:2

Taxonomy

• Homo sapiens (Human)
• Naja kaouthia (Monocled cobra)

Protein

• Carcinoembryonic antigen-related cell adhesion molecule 5 / Homo sapiens    P06731
• CD59 glycoprotein / Homo sapiens    P13987
• Gliomedin [Cleaved into: Gliomedin shedded ectodomain] / Homo sapiens    Q6ZMI3
• Haptoglobin / Homo sapiens    P00738
• Polymeric immunoglobulin receptor / Homo sapiens    P01833
• Prostaglandin-h2 d-isomerase / Homo sapiens    P41222
• Uromodulin / Homo sapiens    P07911
• Cobra venom factor / Naja kaouthia    Q91132

Source

• Ascitic fluid (UBERON_0007795)  
• Blood Serum (UBERON_0001977)  
• Liver (UBERON_0002107)  
• Milk (UBERON_0001913)  
• Urine (UBERON_0001088)  
• Venom (UBERON_0007113)  

Reported structure

• N-Linked / Complex / {Fuc(a1-3)}j[NeuAc(a2-3)Gal(b1-4)]GlcNAc(b1-2)Man(a1-3)[{Fuc(a1-3)}k[NeuAc(a2-3)Gal(b1-4)]GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"where j+k=1.2"
• N-Linked / Complex / Structure 9494

Composition

• Hex:5 HexNAc:4 dHex:3 NeuAc:2 (avg mass : 2662.4521 )

Disease

• Colon adenocarcinoma (DOID:234)
• Prostate cancer (DOID:10283)

Reference

• Carcinoembryonic antigen glycosylation (2021 - Kolarich D) / Status : Reviewed
• Quantitative Longitudinal Inventory of the N-Glycoproteome of Human Milk from a Single Donor Reveals the Highly Variable Repertoire and Dynamic Site-Specific Changes (2020 - Jing Zhu, Yu-Hsien Lin, Kelly A Dingess, Marko Mank, Bernd Stahl, Albert J R Heck) / Status : Reviewed
• Large-scale intact glycopeptide identification by Mascot database search (2018 - Ravi Chand Bollineni, Christian Jeffrey Koehler, Randi Elin Gislefoss, Jan Haug Anonsen, Bernd Thiede) / Status : Unreviewed
• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• N-linked oligosaccharides of cobra venom factor contain novel alpha(1-3)galactosylated Le(x) structures. (2001 - Gowda DC, Glushka J, van-Halbeek H , Thotakura RN, Bredehorst R, Vogel C-W) / Status : Reviewed

Reported glycosite

• Carcinoembryonic antigen-related cell adhesion molecule 5 / Homo sapiens
  •        Undefined site
• CD59 glycoprotein / Homo sapiens
  •        Asn-43
• Gliomedin [Cleaved into: Gliomedin shedded ectodomain] / Homo sapiens
  •        Asn-130
• Haptoglobin / Homo sapiens
  •        Asn-207
• Polymeric immunoglobulin receptor / Homo sapiens
  •        Asn-499
• Prostaglandin-h2 d-isomerase / Homo sapiens
  •        Asn-51
  •        Asn-78
• Uromodulin / Homo sapiens
  •        Asn-513
• Cobra venom factor / Naja kaouthia
  •        Undefined site

Mass spectrometry observed peptide

• TAVNCSSDFDACLITK (16aa)
  •    P13987    Asn-43     CD59 glycoprotein / Homo sapiens
• WFSAGLASNSSWLR (14aa)
  •    P41222    Asn-51     Prostaglandin-h2 d-isomerase / Homo sapiens
• SVVAPATDGGLNLTSTFLR (19aa)
  •    P41222    Asn-78     Prostaglandin-h2 d-isomerase / Homo sapiens
• VMVDLCNSTK (10aa)
  •    Q6ZMI3    Asn-130     Gliomedin [Cleaved into: Gliomedin shedded ectodomain] / Homo sapiens
• KNLFLNHSENATAKD (15aa)
  •    P00738    Asn-207     Haptoglobin / Homo sapiens
• KWNNTGCQALPSQDEGPSKA (20aa)
  •    P01833    Asn-499     Polymeric immunoglobulin receptor / Homo sapiens
• FALLMTNCYATPSSNATDPLK (21aa)
  •    P07911    Asn-513     Uromodulin / Homo sapiens