Hex:4 HexNAc:6 NeuAc:2

Taxonomy

• Homo sapiens (Human)

Protein

• Biglycan / Homo sapiens    P21810
• Fibronectin / Homo sapiens    P02751
• Glycoprotein hormones alpha chain - choriogonadotropin / Homo sapiens    P01215
• Golgi membrane protein 1 / Homo sapiens    Q8NBJ4
• Inositol monophosphatase 3 / Homo sapiens    Q9NX62
• Lumican / Homo sapiens    P51884
• Lutropin beta chain / Homo sapiens    P01229
• Prostate-specific antigen (psa-1) / Homo sapiens    P07288
• Prostate-specific antigen - high Pi isoform (psah) / Homo sapiens    P07288
• Signal transducer CD24 / Homo sapiens    P25063

Source

• Mammary Gland (UBERON_0001911)  
• Pituitary Gland (UBERON_0000007)  
• Seminal Fluid (UBERON_0006530)  

Reported structure

• N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[NeuAc(a2-6)GalNAc(b1-4)GlcNAc(b1-2)Man(a1-3)][GlcNAc(b1-4)]Man(b1-4)GlcNAc(b1-4)GlcNAc

Composition

• Hex:4 HexNAc:6 NeuAc:2 (avg mass : 2468.2707 )

Disease

• Cancer, breast (DOID:1612)

Reference

• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed
• Glycoproteomics: Identifying the Glycosylation of Prostate Specific Antigen at Normal and High Isoelectric Points by LC-MS/MS (2014 - Song E, Mayampurath A, Yu CY, Tang H, Mechref Y) / Status : Reviewed
• NMR investigations of the N-linked oligosaccharides at individual glycosylation sites of human lutropin. (1991 - Weisshaar G, Hiyama J, Renwick A, Nimtz M) / Status : Reviewed

Reported glycosite

• Biglycan / Homo sapiens
  •        Asn-270
  •        Asn-311
• Fibronectin / Homo sapiens
  •        Asn-430
• Glycoprotein hormones alpha chain - choriogonadotropin / Homo sapiens
  •        Asn-76
  •        Asn-102
• Golgi membrane protein 1 / Homo sapiens
  •        Asn-109
• Inositol monophosphatase 3 / Homo sapiens
  •        Asn-259
• Lumican / Homo sapiens
  •        Asn-127
• Lutropin beta chain / Homo sapiens
  •        Asn-50
• Prostate-specific antigen (psa-1) / Homo sapiens
  •        Asn-69
• Prostate-specific antigen - high Pi isoform (psah) / Homo sapiens
  •        Asn-69
• Signal transducer CD24 / Homo sapiens
  •        Asn-52

Mass spectrometry observed peptide

• SETTTGTSSNSSQSTSNSGLAPNPTNATTK (30aa)
  •    P25063    Asn-52     Signal transducer CD24 / Homo sapiens
• AVCGGVLVHPQWVLTAAHCIRNKSVILLGR (30aa)
  •    P07288    Asn-69     Prostate-specific antigen - high Pi isoform (psah) / Homo sapiens
• NKSVLLGR (8aa)
  •    P07288    Asn-69     Prostate-specific antigen - high Pi isoform (psah) / Homo sapiens
  •    P07288    Asn-69     Prostate-specific antigen (psa-1) / Homo sapiens
• AVIVNNITTGER (12aa)
  •    Q8NBJ4    Asn-109     Golgi membrane protein 1 / Homo sapiens
• LHINHNNLTESVGPLPK (17aa)
  •    P51884    Asn-127     Lumican / Homo sapiens
• QVAIQTFGNQTTIIPAGGAGYK (22aa)
  •    Q9NX62    Asn-259     Inositol monophosphatase 3 / Homo sapiens
• MIENGSISFIPTIR (14aa)
  •    P21810    Asn-270     Biglycan / Homo sapiens
• IIQVVYIHSNNITK (14aa)
  •    P21810    Asn-311     Biglycan / Homo sapiens
• LHSNNITK (8aa)
  •    P21810    Asn-311     Biglycan / Homo sapiens
• NYTDCTSEGR (10aa)
  •    P02751    Asn-430     Fibronectin / Homo sapiens