Hex:4 HexNAc:4 dHex:3

Taxonomy

• Homo sapiens (Human)
• Sus scrofa (Pig)

Protein

• Adipocyte plasma membrane-associated protein / Homo sapiens    Q9HDC9
• Alpha-2-macroglobulin / Homo sapiens    P01023
• Basement membrane-specific heparan sulfate proteoglycan core protein / Homo sapiens    P98160
• Beta-glucuronidase / Homo sapiens    P08236
• Biglycan / Homo sapiens    P21810
• Calumenin / Homo sapiens    O43852
• Calumenin, isoform CRA_a / Homo sapiens    
• Cation-independent mannose-6-phosphate receptor / Homo sapiens    P11717
• CD59 glycoprotein / Homo sapiens    P13987
• Clusterin / Homo sapiens    P10909
• Collagen alpha-1(XII) chain / Homo sapiens    Q99715
• Collagen alpha-2(VI) chain / Homo sapiens    P12110
• Decorin / Homo sapiens    P07585
• Desmocollin-2 / Homo sapiens    Q02487
• Dipeptidyl peptidase 1 / Homo sapiens    P53634
• Fibrinogen beta chain / Homo sapiens    P02675
• Fibronectin / Homo sapiens    P02751
• Glucosylceramidase / Homo sapiens    P04062
• Golgi apparatus protein 1 / Homo sapiens    Q92896
• Insulin-like growth factor II / Homo sapiens    P01344
• KDEL motif-containing protein 2 / Homo sapiens    Q7Z4H8
• Klotho / Homo sapiens    Q9UEF7
• Lysosome-associated membrane glycoprotein 1 / Homo sapiens    P11279
• Lysosome-associated membrane glycoprotein 2 / Homo sapiens    P13473
• Mammaglobin-A / Homo sapiens    Q13296
• Periostin / Homo sapiens    Q15063
• Plasma protease c1 inhibitor / Homo sapiens    P05155
• Plexin-B2 / Homo sapiens    O15031
• Prenylcysteine oxidase 1 / Homo sapiens    Q9UHG3
• Prosaposin / Homo sapiens    P07602
• Sortilin / Homo sapiens    Q99523
• Sparc / Homo sapiens    P09486
• Tetraspanin-1 / Homo sapiens    O60635
• Thrombospondin-3 / Homo sapiens    P49746
• Translocon-associated protein subunit alpha / Homo sapiens    P43307
• Uncharacterized protein from Urine / Homo sapiens    
• Unspecified mucin / Homo sapiens    
• Vesicular integral-membrane protein VIP36 / Homo sapiens    Q12907
• Zinc-alpha-2-glycoprotein / Homo sapiens    P25311
• Mucin / Sus scrofa    

Source

• Mammary Gland (UBERON_0001911)  
• Mucosa of Stomach (UBERON_0001199)  
• Pulmonary Mucosa  
• Urine (UBERON_0001088)  

Reported structure

• N-Linked / No-core / Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-6)]Man(a1-6)Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• O-Linked / Core 2 / Fuc(a1-2)Gal(b1-4)GlcNAc(b1-6)[Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-3)[Fuc(a1-2)Gal(b1-4)GlcNAc(b1-6)]GalNAc
• O-Linked / Core 2 / Fuc(a1-2)Gal(b1-4)GlcNAc(b1-6)[Fuc(a1-2)Gal(b1-?)GlcNAc(b1-3)]Gal(b1-3)[Fuc(a1-2)Gal(b1-4)GlcNAc(b1-6)]GalNAc
• O-Linked / Core 2 / Fuc(a1-2)Gal(b1-?)[Fuc(a1-?)]GlcNAc(b1-?)[Fuc(a1-2)Gal(b1-?)GlcNAc(b1-?)]Gal(b1-3)[Gal(b1-4)GlcNAc(b1-6)]GalNAc

Composition

• Hex:4 HexNAc:4 dHex:3 (avg mass : 1917.7939 )

Disease

• Cancer, breast (DOID:1612)
• Cystic Fibrosis (DOID:1485)
• Fucosidosis (DOID:14500)
• Prostate cancer (DOID:10283)

Reference

• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed
• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• Structures of sulfated oligosaccharides in human trachea mucin glycoproteins. (1993 - Sangadala S, Bhat U, Mendicino J) / Status : Reviewed
• Quantitation and structures of oligosaccharide chains in human trachea mucin glycoproteins. (1992 - Sangadala S, Bhat U, Mendicino J) / Status : Reviewed
• Characterization and 400-MHz 1H-NMR analysis of urinary fucosyl glycoasparagines in fucosidosis. (1991 - Michalski J, Wieruszeski J, Alonso C, Cache P, Montreuil J, Strecker G) / Status : Reviewed
• Structures of the oligosaccharide chains in swine trachea mucin glycoproteins. (1984 - Chandrasekaran EV, Rana SS, Davila M, Mendicino J) / Status : Reviewed
• Structural characterization of neutral oligosaccharides of human H+Leb+ gastric mucin. (1984 - Slomiany B, Zdebska E, Slomiany A) / Status : Reviewed

Reported glycosite

• Adipocyte plasma membrane-associated protein / Homo sapiens
  •        Asn-160
• Alpha-2-macroglobulin / Homo sapiens
  •        Asn-869
• Basement membrane-specific heparan sulfate proteoglycan core protein / Homo sapiens
  •        Asn-3780
• Beta-glucuronidase / Homo sapiens
  •        Asn-173
• Biglycan / Homo sapiens
  •        Asn-270
  •        Asn-311
• Calumenin / Homo sapiens
  •        Asn-131
• Calumenin, isoform CRA_a / Homo sapiens
  •        Asn-131
• Cation-independent mannose-6-phosphate receptor / Homo sapiens
  •        Asn-435
  •        Asn-626
• CD59 glycoprotein / Homo sapiens
  •        Thr-40
• Clusterin / Homo sapiens
  •        Asn-103
  •        Asn-354
  •        Asn-374
• Collagen alpha-1(XII) chain / Homo sapiens
  •        Asn-1763
  •        Asn-2528
  •        Asn-2679
• Collagen alpha-2(VI) chain / Homo sapiens
  •        Asn-785
• Decorin / Homo sapiens
  •        Asn-211
• Desmocollin-2 / Homo sapiens
  •        Asn-392
• Dipeptidyl peptidase 1 / Homo sapiens
  •        Asn-276
• Fibrinogen beta chain / Homo sapiens
  •        Asn-394
• Fibronectin / Homo sapiens
  •        Asn-430
  •        Asn-528
• Glucosylceramidase / Homo sapiens
  •        Asn-185
• Golgi apparatus protein 1 / Homo sapiens
  •        Asn-210
• Insulin-like growth factor II / Homo sapiens
  •        Ser-95
• KDEL motif-containing protein 2 / Homo sapiens
  •        Asn-61
• Klotho / Homo sapiens
  •        Asn-159
• Lysosome-associated membrane glycoprotein 1 / Homo sapiens
  •        Asn-84
  •        Asn-249
  •        Asn-261
• Lysosome-associated membrane glycoprotein 2 / Homo sapiens
  •        Asn-123
• Mammaglobin-A / Homo sapiens
  •        Asn-53
• Periostin / Homo sapiens
  •        Asn-599
• Plasma protease c1 inhibitor / Homo sapiens
  •        Ser-36
• Plexin-B2 / Homo sapiens
  •        Asn-1099
• Prenylcysteine oxidase 1 / Homo sapiens
  •        Asn-196
• Prosaposin / Homo sapiens
  •        Asn-101
  •        Asn-215
• Sortilin / Homo sapiens
  •        Asn-162
• Sparc / Homo sapiens
  •        Asn-116
• Tetraspanin-1 / Homo sapiens
  •        Asn-141
  •        Asn-154
• Thrombospondin-3 / Homo sapiens
  •        Asn-407
• Translocon-associated protein subunit alpha / Homo sapiens
  •        Asn-136
• Uncharacterized protein from Urine / Homo sapiens
  •        Undefined site
• Unspecified mucin / Homo sapiens
  •        Undefined site
• Vesicular integral-membrane protein VIP36 / Homo sapiens
  •        Asn-183
• Zinc-alpha-2-glycoprotein / Homo sapiens
  •        Asn-109
  •        Asn-128
• Mucin / Sus scrofa
  •        Undefined site

Mass spectrometry observed peptide

• ASSNPNATSSSSQDPESLQDRGEGK (25aa)
  •    P05155    Ser-36
• TAVNCSSDFDACLITK (16aa)
  •    P13987    Thr-40
• ELLQEFIDDNATTNAIDELK (20aa)
  •    Q13296    Asn-53
• YFYIQAVNSEGQNITR (16aa)
  •    Q7Z4H8    Asn-61
• ENTSDPSIVIAFGR (14aa)
  •    P11279    Asn-84
• SSCGKENTSDPSIVIAFGR (19aa)
  •    P11279    Asn-84
• DVSTPPTVLPDNFPR (15aa)
  •    P01344    Ser-95
• TCDWIPKPNMSASCK (15aa)
  •    P07602    Asn-101
• ELPGVCNETMMALWEECKPCLK (22aa)
  •    P10909    Asn-103
• DIVEYYNDSNGSHVIQGR (18aa)
  •    P25311    Asn-109
• VCSNDNK (7aa)
  •    P09486    Asn-116
• AASTYSIDSVSFSYNTGDNTTFPDAEDK (28aa)
  •    P13473    Asn-123
• FGCEIENNR (9aa)
  •    P25311    Asn-128
• NVTYGTYIDDPDPDDGFNYK (20aa)
  •        Asn-131
  •    O43852    Asn-131
• NATYGYVIDDPDPDDGFNYK (20aa)
  •    O43852    Asn-131
• YPQDYQFYIQNFTAIPINTVVPPQR (25aa)
  •    P43307    Asn-136
• DYGSQEDFTQVWNTTMK (17aa)
  •    O60635    Asn-141
• CCGFTNYTDFEDSPYFK (17aa)
  •    O60635    Asn-154
• NGSAGVPNR (9aa)
  •    Q9UEF7    Asn-159
• AGPNGTIFVADAYK (14aa)
  •    Q9HDC9    Asn-160
• DITDLINNTFIR (12aa)
  •    Q99523    Asn-162
• ITIAINNTLTPTTLPPGTIQYLTDTSK (27aa)
  •    P08236    Asn-173
• VFPYISVMVNNGSISYDHSK (20aa)
  •    Q12907    Asn-183
• TYTYADTPDDFQIHNFSIPEEDTK (24aa)
  •    P04062    Asn-185
• IIHAIGGDDFIGMINR (16aa)
  •    Q9UHG3    Asn-196
• GNITEYQCHQYITK (14aa)
  •    Q92896    Asn-210
• IADTNITSIPQGIPPSITEIHIDGNK (26aa)
  •    P07585    Asn-211
• TNSTFVQALVEHVK (14aa)
  •    P07602    Asn-215
• TNSTFVQAIVEHVKEECDR (19aa)
  •    P07602    Asn-215
• KDNTTVTR (8aa)
  •    P11279    Asn-249
• IININPNK (8aa)
  •    P11279    Asn-261
• MIENGSISFIPTIR (14aa)
  •    P21810    Asn-270
• IITNNSQTPIISPQEVVSCSQYAQGCEGGFPYIIAGK (37aa)
  •    P53634    Asn-276
• IIQVVYIHSNNITK (14aa)
  •    P21810    Asn-311
• MINTSSIIEQINEQFNWVSR (20aa)
  •    P10909    Asn-354
• IANITQGEDQYYIR (14aa)
  •    P10909    Asn-374
• ANYTILK (7aa)
  •    Q02487    Asn-392
• GTAGNAIMDGASQIMGENR (19aa)
  •    P02675    Asn-394
• IGFIGNQSQGCIPAR (15aa)
  •    P49746    Asn-407
• NYTDCTSEGR (10aa)
  •    P02751    Asn-430
• MSVINFECNK (10aa)
  •    P11717    Asn-435
• DQCIVDDITYNVNDTFHK (18aa)
  •    P02751    Asn-528
• EVNDTLLVNELK (12aa)
  •    Q15063    Asn-599
• TEGENCTVFDSQAGFSFDLSPLTK (24aa)
  •    P11717    Asn-626
• NMTLFSDLVAEK (12aa)
  •    P12110    Asn-785
• SLGNVNFTVSAEALESQELCGTEVPSVPEHGRK (33aa)
  •    P01023    Asn-869
• TEAGAFEYVPDPTFENFTGGVK (22aa)
  •    O15031    Asn-1099
• NLQVYNATSNSLTVK (15aa)
  •    Q99715    Asn-1763
• MIEAYNITEK (10aa)
  •    Q99715    Asn-2528
• EAGNITTDGYEIIGK (15aa)
  •    Q99715    Asn-2679
• LAPVNGTSQGK (11aa)
  •    P98160    Asn-3780