Hex:5 HexNAc:4 NeuGc:1

Taxonomy

• Homo sapiens (Human)
• Bos taurus (Bovine)
• Mus musculus (House mouse)
• Ovis aries (Sheep)
• Sus scrofa (Pig)

Protein

• Alpha-2-hs-glycoprotein / Homo sapiens    P02765
• Prostaglandin-h2 d-isomerase / Homo sapiens    P41222
• Protein AMBP / Homo sapiens    P02760
• Alpha-1-acid glycoprotein / Bos taurus    Q3SZR3
• Plasminogen / Bos taurus    P06868
• Zona pellucida sperm-binding protein matrix / Mus musculus    P20239    Q62005    P10761
• Alpha-1-acid glycoprotein / Ovis aries    W5P7S6
• Plasminogen / Sus scrofa    P06867

Source

• Blood Plasma (UBERON_0001969)  
• Blood Serum (UBERON_0001977)  
• Urine (UBERON_0001088)  
• Zona Pellucida (UBERON_0000086)  

Reported structure

• N-Linked / Complex / Gal(b1-4)GlcNAc(?1-?)Man(a1-3)[Gal(b1-4)GlcNAc(?1-?)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ NeuGc(a2-?)"
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-2)Man(a1-?)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / Complex / NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc

Composition

• Hex:5 HexNAc:4 NeuGc:1 (avg mass : 1948.7646 )

Disease

• Prostate cancer (DOID:10283)

Reference

• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• Structural analysis of murine zona pellucida glycans. Evidence for the expression of core 2-type O-glycans and the Sd(a) antigen. (2000 - Easton RL, Patankar MS, Lattanzio FA, Leaven TH, Morris HR, Clark GF, Dell A) / Status : Reviewed
• Structural determination of N-linked carbohydrates by matrix-assisted laser desorption/ionization-mass spectrometry following enzymatic release within sodium dodecyl sulfate-polyacrylamide electrophoresis gels: application to species-specific glycosylation of alpha1-acid glycoprotein. (1998 - Kuster B, Hunter A, Wheeler S, Dwek R, Harvey D) / Status : Reviewed
• The N- and O-linked carbohydrate chains of human, bovine and porcine plasminogen. Species specificity in relation to sialylation and fucosylation patterns. (1988 - Marti T, Schaller J, Rickli E, Schmid K, Kamerling J, Gerwig G, van Halbeek H, Vliegenthart J) / Status : Reviewed

Reported glycosite

• Alpha-2-hs-glycoprotein / Homo sapiens
  •        Asn-156
• Prostaglandin-h2 d-isomerase / Homo sapiens
  •        Asn-78
• Protein AMBP / Homo sapiens
  •        Asn-250
• Alpha-1-acid glycoprotein / Bos taurus
  •        Undefined site
• Plasminogen / Bos taurus
  •        Asn-315
• Zona pellucida sperm-binding protein matrix / Mus musculus
  •        Undefined site
• Alpha-1-acid glycoprotein / Ovis aries
  •        Undefined site
• Plasminogen / Sus scrofa
  •        Asn-289

Mass spectrometry observed peptide

• SVVAPATDGGLNLTSTFLR (19aa)
  •    P41222    Asn-78
• VCQDCPLLAPLNDTR (15aa)
  •    P02765    Asn-156
• YFYNGTSMACETFQYGGCMGNGNNFVTEK (29aa)
  •    P02760    Asn-250