Hex:8 HexNAc:7

Taxonomy

• Homo sapiens (Human)
• Mus musculus (House mouse)
• Rattus norvegicus (Norway rat)

Protein

• 4F2 cell-surface antigen heavy chain / Homo sapiens    P08195
• Alpha-1-acid glycoprotein 2 / Homo sapiens    P19652
• Alpha-1-antichymotrypsin / Homo sapiens    P01011
• Alpha-S1-casein / Homo sapiens    P47710
• Biglycan / Homo sapiens    P21810
• Calcium-activated chloride channel regulator 2 / Homo sapiens    Q9UQC9
• Calumenin / Homo sapiens    O43852
• Cation-independent mannose-6-phosphate receptor / Homo sapiens    P11717
• CD166 antigen / Homo sapiens    Q13740
• CD276 antigen / Homo sapiens    Q5ZPR3
• CD44 antigen / Homo sapiens    P16070
• Chordin-like protein 2 / Homo sapiens    Q6WN34
• Clusterin / Homo sapiens    P10909
• Collagen alpha-1(XII) chain / Homo sapiens    Q99715
• Desmoglein-2 / Homo sapiens    Q14126
• Ectonucleoside triphosphate diphosphohydrolase 2 / Homo sapiens    Q9Y5L3
• Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 / Homo sapiens    P22413
• Erythropoietin / Homo sapiens    P01588
• Fibromodulin / Homo sapiens    Q06828
• Gamma-glutamyltransferase light chain 1 / Homo sapiens    Q9BX51
• Gamma-glutamyltransferase light chain 2 / Homo sapiens    Q14390
• Gamma-glutamyltranspeptidase 1 / Homo sapiens    P19440
• Inactive tyrosine-protein kinase 7 / Homo sapiens    Q13308
• Inositol monophosphatase 3 / Homo sapiens    Q9NX62
• Insulin receptor / Homo sapiens    P06213
• Intercellular adhesion molecule-3 (CD50) / Homo sapiens    P32942
• Lactotransferrin / Homo sapiens    P02788
• Laminin subunit gamma-1 / Homo sapiens    P11047
• Leucyl-cystinyl aminopeptidase / Homo sapiens    Q9UIQ6
• Lipoprotein lipase / Homo sapiens    P06858
• Lysosome membrane protein 2 / Homo sapiens    Q14108
• Lysosome-associated membrane glycoprotein 1 / Homo sapiens    P11279
• Lysosome-associated membrane glycoprotein 2 / Homo sapiens    P13473
• Mammaglobin-A / Homo sapiens    Q13296
• Plexin-B2 / Homo sapiens    O15031
• Prolargin / Homo sapiens    P51888
• Prosaposin / Homo sapiens    P07602
• Prostaglandin F2 receptor negative regulator / Homo sapiens    Q9P2B2
• Receptor-type tyrosine-protein phosphatase C / Homo sapiens    P08575
• Receptor-type tyrosine-protein phosphatase kappa / Homo sapiens    Q15262
• Sortilin / Homo sapiens    Q99523
• Sulfhydryl oxidase 1 / Homo sapiens    O00391
• Tenascin / Homo sapiens    P24821
• Translocon-associated protein subunit alpha / Homo sapiens    P43307
• Transmembrane protein 87A / Homo sapiens    Q8NBN3
• Vasorin / Homo sapiens    Q6EMK4
• Von willebrand factor / Homo sapiens    P04275
• Zinc-alpha-2-glycoprotein / Homo sapiens    P25311
• Uncharacterized protein / Mus musculus    
• Uncharacterized protein from Ascitic fluid / Mus musculus    
• Uncharacterized protein / Rattus norvegicus    
• Uncharacterized protein / Rattus norvegicus    
• Uncharacterized protein / Rattus norvegicus    
• Uncharacterized protein / Rattus norvegicus    

Source

• Ascitic fluid (UBERON_0007795)   EL4 (CVCL_0255)  
• Blood Plasma (UBERON_0001969)  
• Blood Serum (UBERON_0001977)  
• Mammary Gland (UBERON_0001911)  
• Milk (UBERON_0001913)  
• Ovary (UBERON_0000992)   CHO B8-300 (CVCL_VU03)  
• Umbilical Vein (UBERON_0002066)   Endothelial Cell of Umbilical Vein (CL_0002618)  
• 3Y1-B clone 1 (CVCL_4563)  
• BW5147 (CVCL_3896)   T-Lymphocyte (CL_0000084)  
• Erythrocyte (CL_0000232)   Plasma Membrane (GO_0005886)  
• Leukocyte (CL_0000738)  
• T-Lymphocyte (CL_0000084)  

Reported structure

• N-Linked / Complex / Gal(b1-4)GlcNAc(?1-?)[Gal(b1-4)GlcNAc(?1-?)]Man(a1-3)[Gal(b1-4)GlcNAc(?1-?)[Gal(b1-4)GlcNAc(?1-?)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ Gal(b1-4)GlcNAc(?1-?)"
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-2)[Gal(b1-4)GlcNAc(b1-4)]Man(a1-3)[Gal(b1-4)GlcNAc(b1-2)[Gal(b1-4)GlcNAc(b1-6)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ Gal(b1-4)GlcNAc(b1-3)"
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-2)[Gal(b1-4)GlcNAc(b1-4)]Man(a1-?)[Gal(b1-4)GlcNAc(b1-2)[Gal(b1-4)GlcNAc(b1-6)]Man(a1-?)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ Gal(b1-3)GlcNAc(b1-3)"
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-2)[Gal(b1-4)GlcNAc(b1-4)]Man(a1-?)[Gal(b1-4)GlcNAc(b1-2)[Gal(b1-4)GlcNAc(b1-6)]Man(a1-?)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ Gal(b1-4)GlcNAc(b1-3)"
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-2)[Gal(b1-4)GlcNAc(b1-4)]Man(a1-?)[Gal(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ 2 x Gal(b1-4)GlcNAc(b1-3)"
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-2)[Gal(b1-4)GlcNAc(b1-6)]Man(a1-6)[Gal(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ 2 x Gal(b1-4)GlcNAc(b1-3)"
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)[Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-4)[Gal(b1-4)GlcNAc(b1-6)]Man(a1-3)[Gal(b1-4)GlcNAc(b1-2)[Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-6)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-4)[Gal(b1-4)GlcNAc(b1-6)]Man(a1-3)[Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-2)[Gal(b1-4)GlcNAc(b1-6)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / Complex / Structure 9427

Composition

• Hex:8 HexNAc:7 (avg mass : 2737.5195 )

Disease

• Cancer, breast (DOID:1612)
• Lymphoma, Lymphoblastic (DOID:0080147)
• Lymphoma, Thymic (DOID:10146)

Reference

• Quantitative Longitudinal Inventory of the N-Glycoproteome of Human Milk from a Single Donor Reveals the Highly Variable Repertoire and Dynamic Site-Specific Changes (2020 - Jing Zhu, Yu-Hsien Lin, Kelly A Dingess, Marko Mank, Bernd Stahl, Albert J R Heck) / Status : Reviewed
• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed
• Glycoproteomic analysis of the secretome of human endothelial cells (2013 - Yin X, Bern M, Xing Q, Ho J, Viner R, Mayr M.) / Status : Reviewed
• Structural study of N-linked oligosaccharides of human intercellular adhesion molecule-3 (CD50). (2001 - Funatsu O, Sato T, Kotovuori P, Gahmberg CG, Ikekita M, Furukawa K) / Status : Reviewed
• Structural determination of N-linked carbohydrates by matrix-assisted laser desorption/ionization-mass spectrometry following enzymatic release within sodium dodecyl sulfate-polyacrylamide electrophoresis gels: application to species-specific glycosylation of alpha1-acid glycoprotein. (1998 - Kuster B, Hunter A, Wheeler S, Dwek R, Harvey D) / Status : Reviewed
• Structural study of the sugar chains of human leukocyte common antigen CD45. (1993 - Sato T, Furukawa K, Autero M, Gahmberg C, Kobata A) / Status : Reviewed
• Structures of the asparagine-linked oligosaccharide chains of human von Willebrand factor. Occurrence of blood group A, B, and H(O) structures. (1992 - Matsui T, Titani K, Mizuochi T) / Status : Reviewed
• Cell type and maturation stage-dependent polymorphism of N-linked oligosaccharides on murine lymphocytes and lymphoma cells. (1991 - Yoshida T, Takahashi N, Nakashima I) / Status : Reviewed
• Transfection with fragments of the adenovirus 12 gene induces tumorigenicity-associated alteration of N-linked sugar chains in rat cells. (1990 - Hiraizumi S, Takasaki S, Shiroki K, Kochibe N, Kobata A) / Status : Reviewed
• Relationship between sugar chain structure and biological activity of recombinant human erythropoietin produced in Chinese hamster ovary cells. (1989 - Takeuchi M, Inoue N, Strickland T, Kubota M, Wada M, Shimizu R, Hoshi S, Kozutsumi H, Takasaki S, Kobata A) / Status : Reviewed
• The asparagine-linked sugar chains of the glycoproteins in rat erythrocyte plasma membrane--fractionation of oligosaccharides liberated by hydrazinolysis and structural studies of the neutral oligosaccharides. (1982 - Matsumoto A, Yoshima H, Maeda S, Shiraishi N, Kobata A) / Status : Reviewed
• Comparative study of the carbohydrate moieties of rat and human plasma alpha 1-acid glycoproteins. (1981 - Yoshima H, Matsumoto A, Mizuochi T, Kawasaki T, Kobata A) / Status : Reviewed

Reported glycosite

• 4F2 cell-surface antigen heavy chain / Homo sapiens
  •        Asn-365
• Alpha-1-acid glycoprotein 2 / Homo sapiens
  •        Undefined site
• Alpha-1-antichymotrypsin / Homo sapiens
  •        Asn-106
  •        Asn-271
• Alpha-S1-casein / Homo sapiens
  •        Asn-69
• Biglycan / Homo sapiens
  •        Asn-311
• Calcium-activated chloride channel regulator 2 / Homo sapiens
  •        Asn-637
• Calumenin / Homo sapiens
  •        Asn-131
• Cation-independent mannose-6-phosphate receptor / Homo sapiens
  •        Asn-626
• CD166 antigen / Homo sapiens
  •        Asn-306
  •        Asn-361
• CD276 antigen / Homo sapiens
  •        Asn-215
• CD44 antigen / Homo sapiens
  •        Asn-57
• Chordin-like protein 2 / Homo sapiens
  •        Asn-114
• Clusterin / Homo sapiens
  •        Asn-86
  •        Asn-103
  •        Asn-374
• Collagen alpha-1(XII) chain / Homo sapiens
  •        Asn-2679
• Desmoglein-2 / Homo sapiens
  •        Asn-462
• Ectonucleoside triphosphate diphosphohydrolase 2 / Homo sapiens
  •        Asn-294
  •        Asn-378
• Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 / Homo sapiens
  •        Asn-285
• Erythropoietin / Homo sapiens
  •        Undefined site
• Fibromodulin / Homo sapiens
  •        Asn-166
• Gamma-glutamyltransferase light chain 1 / Homo sapiens
  •        Asn-167
• Gamma-glutamyltransferase light chain 2 / Homo sapiens
  •        Asn-160
• Gamma-glutamyltranspeptidase 1 / Homo sapiens
  •        Asn-511
• Inactive tyrosine-protein kinase 7 / Homo sapiens
  •        Asn-116
• Inositol monophosphatase 3 / Homo sapiens
  •        Asn-259
• Insulin receptor / Homo sapiens
  •        Asn-424
• Intercellular adhesion molecule-3 (CD50) / Homo sapiens
  •        Undefined site
• Lactotransferrin / Homo sapiens
  •        Asn-156
• Laminin subunit gamma-1 / Homo sapiens
  •        Asn-1395
• Leucyl-cystinyl aminopeptidase / Homo sapiens
  •        Asn-834
  •        Asn-850
• Lipoprotein lipase / Homo sapiens
  •        Asn-70
• Lysosome membrane protein 2 / Homo sapiens
  •        Asn-304
• Lysosome-associated membrane glycoprotein 1 / Homo sapiens
  •        Asn-84
  •        Asn-249
  •        Asn-261
• Lysosome-associated membrane glycoprotein 2 / Homo sapiens
  •        Asn-58
  •        Asn-275
  •        Asn-356
• Mammaglobin-A / Homo sapiens
  •        Asn-53
• Plexin-B2 / Homo sapiens
  •        Asn-127
• Prolargin / Homo sapiens
  •        Asn-327
• Prosaposin / Homo sapiens
  •        Asn-80
  •        Asn-101
• Prostaglandin F2 receptor negative regulator / Homo sapiens
  •        Asn-286
  •        Asn-413
• Receptor-type tyrosine-protein phosphatase C / Homo sapiens
  •        Undefined site
• Receptor-type tyrosine-protein phosphatase kappa / Homo sapiens
  •        Asn-211
• Sortilin / Homo sapiens
  •        Asn-98
• Sulfhydryl oxidase 1 / Homo sapiens
  •        Asn-130
• Tenascin / Homo sapiens
  •        Asn-1093
• Translocon-associated protein subunit alpha / Homo sapiens
  •        Asn-136
• Transmembrane protein 87A / Homo sapiens
  •        Asn-127
• Vasorin / Homo sapiens
  •        Asn-117
• Von willebrand factor / Homo sapiens
  •        Undefined site
  •        Asn-156
• Zinc-alpha-2-glycoprotein / Homo sapiens
  •        Asn-112
  •        Asn-128
• Uncharacterized protein / Mus musculus
  •        Undefined site
• Uncharacterized protein from Ascitic fluid / Mus musculus
  •        Undefined site
• Uncharacterized protein / Rattus norvegicus
  •        Undefined site
• Uncharacterized protein / Rattus norvegicus
  •        Undefined site
• Uncharacterized protein / Rattus norvegicus
  •        Undefined site
• Uncharacterized protein / Rattus norvegicus
  •        Undefined site

Mass spectrometry observed peptide

• ELLQEFIDDNATTNAIDELK (20aa)
  •    Q13296    Asn-53     Mammaglobin-A / Homo sapiens
• AFNSTLPTMAQMEK (14aa)
  •    P16070    Asn-57     CD44 antigen / Homo sapiens
• YETTNK (6aa)
  •    P13473    Asn-58     Lysosome-associated membrane glycoprotein 2 / Homo sapiens
• KDTRNESTQNCVVAEPEKM (19aa)
  •    P47710    Asn-69     Alpha-S1-casein / Homo sapiens
• RTPEDTAEDTCHLIPGVAESVATCHFNHSSKT (32aa)
  •    P06858    Asn-70     Lipoprotein lipase / Homo sapiens
• DVVTAAGDMIKDNATEEEIIVYIEK (25aa)
  •    P07602    Asn-80     Prosaposin / Homo sapiens
• SSCGKENTSDPSIVIAFGR (19aa)
  •    P11279    Asn-84     Lysosome-associated membrane glycoprotein 1 / Homo sapiens
• KEDALNETR (9aa)
  •    P10909    Asn-86     Clusterin / Homo sapiens
• IANNTHQHVFDDIR (14aa)
  •    Q99523    Asn-98     Sortilin / Homo sapiens
• TCDWIPKPNMSASCK (15aa)
  •    P07602    Asn-101     Prosaposin / Homo sapiens
• ELPGVCNETMMALWEECKPCLK (22aa)
  •    P10909    Asn-103     Clusterin / Homo sapiens
• KFNLTETSEAEIHQSFQHLLRT (22aa)
  •    P01011    Asn-106     Alpha-1-antichymotrypsin / Homo sapiens
• KDIVEYYNDSNGSHVLQGRF (20aa)
  •    P25311    Asn-112     Zinc-alpha-2-glycoprotein / Homo sapiens
• KSCQHNGTMYQHGEIFSAHELFPSRL (26aa)
  •    Q6WN34    Asn-114     Chordin-like protein 2 / Homo sapiens
• SANASFNIK (9aa)
  •    Q13308    Asn-116     Inactive tyrosine-protein kinase 7 / Homo sapiens
• IHEITNETFR (10aa)
  •    Q6EMK4    Asn-117     Vasorin / Homo sapiens
• IFQNCSEIFK (10aa)
  •    Q8NBN3    Asn-127     Transmembrane protein 87A / Homo sapiens
• AISNISIR (8aa)
  •    O15031    Asn-127     Plexin-B2 / Homo sapiens
• FGCEIENNR (9aa)
  •    P25311    Asn-128     Zinc-alpha-2-glycoprotein / Homo sapiens
• KNGSGAVFPVAGADVQTLRE (20aa)
  •    O00391    Asn-130     Sulfhydryl oxidase 1 / Homo sapiens
• NATYGYVIDDPDPDDGFNYK (20aa)
  •    O43852    Asn-131     Calumenin / Homo sapiens
• IQNFTALPLNTVVPPQR (17aa)
  •    P43307    Asn-136     Translocon-associated protein subunit alpha / Homo sapiens
• RTAGWNVPIGTLRPFLNWTGPPEPIEAAVARF (32aa)
  •    P02788    Asn-156     Lactotransferrin / Homo sapiens
• TAGWNVPIGTIRPFINWTGPPEPIEAAVAR (30aa)
  •    P02788    Asn-156     Lactotransferrin / Homo sapiens
• IYIDHNNITR (10aa)
  •    Q06828    Asn-166     Fibromodulin / Homo sapiens
• LGDVEVNAGQNATFQCIATGR (21aa)
  •    Q15262    Asn-211     Receptor-type tyrosine-protein phosphatase kappa / Homo sapiens
• VVIGANGTYSCIVR (14aa)
  •    Q5ZPR3    Asn-215     CD276 antigen / Homo sapiens
• KDNTTVTR (8aa)
  •    P11279    Asn-249     Lysosome-associated membrane glycoprotein 1 / Homo sapiens
• FGNQTTIIPAGGAGYK (16aa)
  •    Q9NX62    Asn-259     Inositol monophosphatase 3 / Homo sapiens
• IININPNK (8aa)
  •    P11279    Asn-261     Lysosome-associated membrane glycoprotein 1 / Homo sapiens
• KYTGNASALFILPDQDKM (18aa)
  •    P01011    Asn-271     Alpha-1-antichymotrypsin / Homo sapiens
• LNSSTIK (7aa)
  •    P13473    Asn-275     Lysosome-associated membrane glycoprotein 2 / Homo sapiens
• MNASFSLK (8aa)
  •    P22413    Asn-285     Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 / Homo sapiens
• NVSVAEGK (8aa)
  •    Q9P2B2    Asn-286     Prostaglandin F2 receptor negative regulator / Homo sapiens
• GFSTQVLLGDVYQSPCTMAQRPQNFNSSAR (30aa)
  •    Q9Y5L3    Asn-294     Ectonucleoside triphosphate diphosphohydrolase 2 / Homo sapiens
• YKVPAEILANTSDNAGFCIPEGN (23aa)
  •    Q14108    Asn-304     Lysosome membrane protein 2 / Homo sapiens
• NATGDYK (7aa)
  •    Q13740    Asn-306     CD166 antigen / Homo sapiens
• IIQVVYIHSNNITK (14aa)
  •    P21810    Asn-311     Biglycan / Homo sapiens
• INGTQICPNDIVAFHDFSSDIENVPHIR (28aa)
  •    P51888    Asn-327     Prolargin / Homo sapiens
• VQPFNVTQGK (10aa)
  •    P13473    Asn-356     Lysosome-associated membrane glycoprotein 2 / Homo sapiens
• NATVVWMK (8aa)
  •    Q13740    Asn-361     CD166 antigen / Homo sapiens
• DASSFIAEWQNITK (14aa)
  •    P08195    Asn-365     4F2 cell-surface antigen heavy chain / Homo sapiens
• RLANLTQGEDQYYLRV (16aa)
  •    P10909    Asn-374     Clusterin / Homo sapiens
• TSMGLPVATLQQLEAAAVNVCNQTWAQLQAR (31aa)
  •    Q9Y5L3    Asn-378     Ectonucleoside triphosphate diphosphohydrolase 2 / Homo sapiens
• VAEAVSSPAGVGVTWIEPDYQVYINASK (28aa)
  •    Q9P2B2    Asn-413     Prostaglandin F2 receptor negative regulator / Homo sapiens
• GETIEIGNYSFYAIDNQNIR (20aa)
  •    P06213    Asn-424     Insulin receptor / Homo sapiens
• YVQNGTYTVK (10aa)
  •    Q14126    Asn-462     Desmoglein-2 / Homo sapiens
• IHNQIIPNVTTVER (14aa)
  •    P19440    Asn-511     Gamma-glutamyltranspeptidase 1 / Homo sapiens
  •    Q9BX51    Asn-167     Gamma-glutamyltransferase light chain 1 / Homo sapiens
  •    Q14390    Asn-160     Gamma-glutamyltransferase light chain 2 / Homo sapiens
• TEGENCTVFDSQAGFSFDLSPLTK (24aa)
  •    P11717    Asn-626     Cation-independent mannose-6-phosphate receptor / Homo sapiens
• QGFYPILNATVTATVEPETGDPVTLR (26aa)
  •    Q9UQC9    Asn-637     Calcium-activated chloride channel regulator 2 / Homo sapiens
• SAIIEFACTHNIGNCSTTAMK (21aa)
  •    Q9UIQ6    Asn-834     Leucyl-cystinyl aminopeptidase / Homo sapiens
• IFDDWMASNGTQSIPTDVMTTVFK (24aa)
  •    Q9UIQ6    Asn-850     Leucyl-cystinyl aminopeptidase / Homo sapiens
• LNWTAADQAYEHFIIQVQEANK (22aa)
  •    P24821    Asn-1093     Tenascin / Homo sapiens
• KIPAINQTITEANEK (15aa)
  •    P11047    Asn-1395     Laminin subunit gamma-1 / Homo sapiens
• EAGNITTDGYEIIGK (15aa)
  •    Q99715    Asn-2679     Collagen alpha-1(XII) chain / Homo sapiens