GlyConnect

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taxonomy (10) protein (15) source (21) structure (27) composition (1) disease (7) reference (24) site (19) peptide (4)

Taxonomy

Protein

Source

Reported structure

Composition

Hex:2 HexNAc:3 dHex:1 (avg mass : 1098.0281 )

Disease

Reference

Colorectal cancer cell lines show striking diversity of their O-glycome reflecting the cellular differentiation phenotype (2021 - Katarina Madunić, Tao Zhang, Oleg A Mayboroda, Stephanie Holst, Kathrin Stavenhagen, Chunsheng Jin, Niclas G Karlsson, Guinevere S M Lageveen-Kammeijer, Manfred Wuhrer) / Status : Reviewed
Identification of 22 N-glycosites on spike glycoprotein of SARS-CoV-2 and accessible surface glycopeptide motifs: Implications for vaccination and antibody therapeutics (2020 - Dapeng Zhou, Xiaoxu Tian, Ruibing Qi, Chao Peng, Wen Zhang) / Status : Reviewed
A novel, ultrasensitive approach for quantitative carbohydrate composition and linkage analysis using LC-ESI ion trap tandem mass spectrometry (2019 - Kathirvel Alagesan, Daniel Varon Silva, Peter H Seeberger, Daniel Kolarich) / Status : Reviewed
Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
Dynamic Developmental Elaboration of N-Linked Glycan Complexity in the Drosophila melanogaster Embryo (2007 - Kazuhiro Aoki, Mindy Perlman, Jae-Min Lim, Rebecca Cantu, Lance Wells, Michael Tiemeyer) / Status : Reviewed
Identification of the blood group Lewis(a) determinant in the oviducal mucins of Xenopus tropicalis. (2003 - Guérardel Y, Petit D, Madigou T, Guillet B, Maes E, Maftah A, Boujard D, Strecker G, Kol O) / Status : Reviewed
Species specificity of O-linked carbohydrate chains of the oviducal mucins in amphibians: structural analysis of neutral oligosaccharide alditols released by reductive beta-elimination from the egg-jelly coats of Rana clamitans. (2002 - Delplace F, Maes E, Lemoine J, Strecker G) / Status : Reviewed
Structural analysis of oligosaccharide-alditols released by reductive beta-elimination from oviducal mucins of Bufo bufo: characterization of the carbohydrate sequence Gal(alpha1-3)GalNAc(alpha1-3)[Fuc(alpha1-2)]Gal. (1997 - Morelle W, Strecker G) / Status : Reviewed
The glycosylation of rat intestinal Muc2 mucin varies between rat strains and the small and large intestine. A study of O-linked oligosaccharides by a mass spectrometric approach. (1997 - Karlsson N, Herrmann A, Karlsson H, Johansson M, Carlstedt I, Hansson G) / Status : Reviewed
Structural analysis of hexa to dodecaoligosaccharide-alditols released by reductive beta-elimination from oviducal mucins of Bufo bufo. (1997 - Morelle W, Strecker G) / Status : Reviewed
Peripheral alpha-linked N-acetylglucosamine on the carbohydrate moiety of mucin derived from mammalian gastric gland mucous cells: epitope recognized by a newly characterized monoclonal antibody. (1996 - Ishihara K, Kurihara M, Goso Y, Urata T, Ota H, Katsuyama T, Hotta K) / Status : Reviewed
Characterization of two different glycosylated domains from the insoluble mucin complex of rat small intestine. (1993 - Carlstedt I, Herrmann A, Karlsson H, Sheehan J, Fransson L, Hansson G) / Status : Reviewed
Human non-secretory ribonucleases. II. Structural characterization of the N-glycans of the kidney, liver and spleen enzymes by NMR spectroscopy and electrospray mass spectrometry. (1993 - Lawrence C, Little P, Little B, Glushka J, van Halbeek H, Alhadeff J) / Status : Reviewed
Structure of ten free N-glycans in ripening tomato fruit. Arabinose is a constituent of a plant N-glycan. (1993 - Priem B, Gitti R, Bush C, Gross K) / Status : Reviewed
Studies on cervical glycoproteins: isolation and characterisation of oligosaccharides from luteal phase cervical glycoproteins of bonnet monkey. (1993 - Nasir-Ud-Din , Walker-Nasir E, Fayyaz-Ud-Din) / Status : Reviewed
The broad diversity of neutral and sialylated oligosaccharides derived from human salivary mucins. (1992 - Klein A, Carnoy C, Wieruszeski J, Strecker G, Strang A, van Halbeek H, Roussel P, Lamblin G) / Status : Reviewed
Quantitation and structures of oligosaccharide chains in human trachea mucin glycoproteins. (1992 - Sangadala S, Bhat U, Mendicino J) / Status : Reviewed
Primary structure of neutral oligosaccharides derived from respiratory-mucus glycoproteins of a patient suffering from bronchiectasis, determined by combination of 500-MHz 1H-NMR spectroscopy and quantitative sugar analysis. 2. Structure of 19 oligosaccharides having the GlcNAc beta(1----3)GalNAc-ol (1988 - Breg J, Van Halbeek H, Vliegenthart J, Klein A, Lamblin G, Roussel P) / Status : Reviewed
Chemical structure of neutral sugar chains isolated from human mature milk kappa-casein. (1988 - Saito T, Itoh T, Adachi S) / Status : Reviewed
Characterization of the oligosaccharide alditols from ovarian cyst mucin glycoproteins of blood group A using high pressure liquid chromatography (HPLC) and high field 1H NMR spectroscopy. (1986 - Dua VK, Rao BN, Wu SS, Dube VE, Bush CA) / Status : Reviewed
Purification and structures of oligosaccharide chains in swine trachea and Cowper's gland mucin glycoproteins. (1984 - Rana SS, Chandrasekaran EV, Kennedy J, Mendicino J) / Status : Reviewed
Further characterization, by a combined high-performance liquid chromatography/1H-NMR approach, of the heterogeneity displayed by the neutral carbohydrate chains of human bronchial mucins. (1984 - Lamblin G, Boersma A, Lhermitte M, Roussel P, Mutsaers J, van Halbeek H, Vliegenthart J) / Status : Reviewed
Structures of the neutral oligosaccharides isolated from A-active human gastric mucin. (1984 - Slomiany A, Zdebska E, Slomiany BL) / Status : Reviewed
Terminal alpha (1 leads to 4)-linked N-acetylglucosamine: a characteristic constituent of duodenal-gland mucous glycoproteins in rat and pig. A high-resolution 1H-NMR study. (1983 - van Halbeek H, Gerwig G, Vliegenthart J, Smits H, Van Kerkhof P, Kramer M) / Status : Reviewed

Reported glycosite

CD59 glycoprotein / Homo sapiens
- Thr-105
Glycoprotein rg / Homo sapiens
- Undefined site
Immunoglobulin heavy constant gamma 2 / Homo sapiens
- Undefined site
Kappa casein / Homo sapiens
- Undefined site
Non-secretory ribonuclease / Homo sapiens
- Undefined site
Unspecified mucin / Homo sapiens
- Undefined site
Uromodulin / Homo sapiens
- Thr-277
- Thr-296
- Ser-301
- Thr-504
- Ser-511
Mucin / Macaca radiata
- Undefined site
Mucin / Rattus norvegicus
- Undefined site
Mucin-2 glycopeptide a / Rattus norvegicus
- Undefined site
Mucin-2 glycopeptide b / Rattus norvegicus
- Undefined site
Mucin / Sus scrofa
- Undefined site
Mucin / Bufo bufo
- Undefined site
Mucin / Rana clamitans
- Undefined site
Mucin / Xenopus tropicalis
- Undefined site

Mass spectrometry observed peptide

HAIHVSGTNGTK (12aa)
DLCNFNEQLENGGTSLSEK (19aa)
- P13987 Thr-105 CD59 glycoprotein / Homo sapiens
ACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDCKSNNGR (47aa)
- P07911 Thr-277 Uromodulin / Homo sapiens
- P07911 Ser-301 Uromodulin / Homo sapiens
- P07911 Thr-296 Uromodulin / Homo sapiens
FALLMTNCYATPSSNATDPLKYFIIQDR (28aa)
- P07911 Thr-504 Uromodulin / Homo sapiens
- P07911 Ser-511 Uromodulin / Homo sapiens

- N-Linked / Complex (avg mass : 1098.0281)
- N-Linked / Hybrid (avg mass : 1098.0281)
- N-Linked / No-core (avg mass : 1098.0281)
- N-Linked / No-core (avg mass : 1098.0281)
- O-Linked / Core 1 (avg mass : 1098.0281)
- O-Linked / Core 1 (avg mass : 1098.0281)
- O-Linked / Core 2 (avg mass : 1098.0281)
- O-Linked / Core 2 (avg mass : 1098.0281)
- O-Linked / Core 2 (avg mass : 1098.0281)
- O-Linked / Core 2 (avg mass : 1098.0281)
- O-Linked / Core 2 (avg mass : 1098.0281)
- O-Linked / Core 2 (avg mass : 1098.0281)
- O-Linked / Core 2 (avg mass : 1098.0281)
- O-Linked / Core 2 (avg mass : 1098.0281)
- O-Linked / Core 2 (avg mass : 1098.0281)
- O-Linked / Core 2 (avg mass : 1098.0281)
- O-Linked / Core 2 (avg mass : 1098.0281)
- O-Linked / Core 2 (avg mass : 1098.0281)
- O-Linked / Core 4 (avg mass : 1098.0281)
- O-Linked / Core 4 (avg mass : 1098.0281)
- O-Linked / Core 4 (avg mass : 1098.0281)
- O-Linked / Core 4 (avg mass : 1098.0281)
- O-Linked / Core 4 (avg mass : 1098.0281)
- O-Linked / Core 4 (avg mass : 1098.0281)
- O-Linked / Undefined core (avg mass : 1098.0281)
- O-Linked / Undefined core (avg mass : 1098.0281)
- O-Linked / Undefined core (avg mass : 1098.0281)