Hex:1 HexNAc:2 dHex:2

Taxonomy

• Homo sapiens (Human)
• Xenopus laevis (African clawed frog)
• Androctonus australis hector (Sahara scorpion)
• Apis mellifera (Honeybee)
• Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)

Protein

• Unspecified mucin / Homo sapiens    
• Uromodulin / Homo sapiens    P07911
• Mucin / Xenopus laevis    
• Toxin Aah6 / Androctonus australis hector    P56743
• Hyaluronoglucosaminidase / Apis mellifera    Q08169
• Recombinant Spike glycoprotein (BTI-Tn-5B1-4) / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)    P0DTC2

Source

• Pulmonary Mucosa  
• Saliva (UBERON_0001836)  
• Substantia Nigra (UBERON_0002038)  
• Urine (UBERON_0001088)  
• Venom (UBERON_0007113)  
• BTI-Tn-5B1-4 (CVCL_C190)  
• Egg Cell   Jelly Coat  

Reported structure

• N-Linked / No-core / Man(b1-4)GlcNAc(b1-4)[Fuc(a1-3)][Fuc(a1-6)]GlcNAc
• N-Linked / Pauci-Mannose / Structure 10056
• O-Linked / Core 2 / Fuc(a1-2)Gal(b1-3)[Fuc(a1-3)GlcNAc(b1-6)]GalNAc
• O-Linked / Core 3 / Fuc(a1-2)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)GalNAc
• O-Linked / No-core / Fuc(?1-?)GlcNAc(?1-?)GalNAc(?1-?)[Fuc(?1-?)]Gal
• O-Linked / No-core / Fuc(a1-3)GlcNAc(a1-3)GalNAc(a1-3)[Fuc(a1-2)]Gal
• O-Linked / O-Man / Structure 11412

Composition

• Hex:1 HexNAc:2 dHex:2 (avg mass : 878.8337 )

Disease

• Bronchiectasis, due to Kartagener's Syndrome
• COVID-19 (DOID:0080600)
• Parkinson's disease (DOID:14330)
• Prostate cancer (DOID:10283)

Reference

• The O-Glycome of Human Nigrostriatal Tissue and Its Alteration in Parkinson's Disease. (2021 - Wilkinson H, Thomsson KA, Rebelo AL, Hilliard M, Pandit A, Rudd PM, Karlsson NG, Saldova R.) / Status : Unreviewed
• Site-specific N-glycosylation Characterization of Recombinant SARS-CoV-2 Spike Proteins using High-Resolution Mass Spectrometry (2020 - Yong Zhang, Wanjun Zhao, Yonghong Mao, Shisheng Wang, Yi Zhong, Tao Su, Meng Gong, Xiaofeng Lu, Jingqiu Cheng, Hao Yang) / Status : Reviewed
• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• O-glycan variability of egg-jelly mucins from Xenopus laevis: characterization of four phenotypes that differ by the terminal glycosylation of their mucins (2000 - Guerardel, Kol, Maes, Lefebvre, Boilly, Davril, Strecker) / Status : Reviewed
• Aah VI, a novel, N-glycosylated anti-insect toxin from Androctonus australis hector scorpion venom: isolation, characterisation, and glycan structure determination. (1999 - Hassani O, Loew D, Van Dorsselaer A, Papandrou M, Sorokine O, Rochat H, Sampieri F, Mansuelle P) / Status : Reviewed
• Characterization of neutral oligosaccharide-alditols from Xenopus laevis egg jelly coats by matrix-assisted laser desorption Fourier transform mass spectrometry. (1997 - Tseng K, Lindsay L, Penn S, Hedrick J, Lebrilla C) / Status : Reviewed
• The asparagine-linked carbohydrate of honeybee venom hyaluronidase. (1995 - Kubelka V, Altmann F, Mrz L) / Status : Reviewed
• The broad diversity of neutral and sialylated oligosaccharides derived from human salivary mucins. (1992 - Klein A, Carnoy C, Wieruszeski J, Strecker G, Strang A, van Halbeek H, Roussel P, Lamblin G) / Status : Reviewed
• Primary structure of neutral oligosaccharides derived from respiratory-mucus glycoproteins of a patient suffering from bronchiectasis, determined by combination of 500-MHz 1H-NMR spectroscopy and quantitative sugar analysis. 2. Structure of 19 oligosaccharides having the GlcNAc beta(1----3)GalNAc-ol (1988 - Breg J, Van Halbeek H, Vliegenthart J, Klein A, Lamblin G, Roussel P) / Status : Reviewed

Reported glycosite

• Unspecified mucin / Homo sapiens
  •        Undefined site
• Uromodulin / Homo sapiens
  •        Thr-234
• Mucin / Xenopus laevis
  •        Undefined site
• Toxin Aah6 / Androctonus australis hector
  •        Asn-9
• Hyaluronoglucosaminidase / Apis mellifera
  •        Undefined site
• Recombinant Spike glycoprotein (BTI-Tn-5B1-4) / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
  •        Asn-1074
  •        Asn-1173

Mass spectrometry observed peptide

• CNTAAPMWLNGTHPSSDEGIVSR (23aa)
  •    P07911    Thr-234     Uromodulin / Homo sapiens
• KNFTTAPAICHDGK (14aa)
  •    P0DTC2    Asn-1074     Recombinant Spike glycoprotein (BTI-Tn-5B1-4) / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
• NHTSPDVDLGDISGINASVVNIQK (24aa)
  •    P0DTC2    Asn-1173     Recombinant Spike glycoprotein (BTI-Tn-5B1-4) / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)