Hex:5 HexNAc:4 dHex:1 NeuGc:2

Taxonomy

• Homo sapiens (Human)
• Bos taurus (Bovine)
• Hybrid - homo sapiens/mus musculus (Hybrid - human/mouse)
• Mus musculus (House mouse)
• Sus scrofa (Pig)

Protein

• Alpha-2-HS-glycoprotein / Homo sapiens    P02765
• CD59 glycoprotein / Homo sapiens    P13987
• Kininogen-1 / Homo sapiens    P01042
• Prostaglandin-h2 d-isomerase / Homo sapiens    P41222
• Uromodulin / Homo sapiens    P07911
• Plasminogen / Bos taurus    P06868
• Immunoglobulin gamma-1 lambda antibody (cbga1) / Hybrid - homo sapiens/mus musculus    
• Alpha-1-acid glycoprotein 1 / Mus musculus    Q60590
• Alpha-1-antitrypsin 1-2 / Mus musculus    P22599
• Alpha-2-hs-glycoprotein / Mus musculus    P29699
• Beta-2-glycoprotein 1 / Mus musculus    Q01339
• Ceruloplasmin / Mus musculus    Q61147
• Complement c4-b / Mus musculus    P01029
• Complement factor h / Mus musculus    P06909
• Immunoglobulin gamma-2 chain c region / Mus musculus    P01859
• Immunoglobulin gamma-2b chain c region / Mus musculus    P01867
• Immunoglobulin j chain / Mus musculus    P01592
• Inter-alpha-trypsin inhibitor heavy chain h3 / Mus musculus    Q61704
• Pregnancy zone protein / Mus musculus    Q61838
• Serotransferrin / Mus musculus    Q921I1
• Zona pellucida sperm-binding protein matrix / Mus musculus    P20239    P10761    Q62005
• Plasminogen / Sus scrofa    P06867
• Vitronectin / Sus scrofa    P48819

Source

• Blood Plasma (UBERON_0001969)  
• Blood Serum (UBERON_0001977)  
• Urine (UBERON_0001088)  
• Zona Pellucida (UBERON_0000086)  

Reported structure

• N-Linked / Complex / NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(?1-6)]GlcNAc
• N-Linked / Complex / NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Structure 430
• N-Linked / Complex / NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / NeuGc(a2-?)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuGc(a2-?)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc

Composition

• Hex:5 HexNAc:4 dHex:1 NeuGc:2 (avg mass : 2402.1649 )

Disease

• Prostate cancer (DOID:10283)

Reference

• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• Sialic acid-focused quantitative mouse serum glycoproteomics by multiple reaction monitoring assay. (2010 - Kurogochi M, Matsushista T, Amano M, Furukawa J, Shinohara Y, Aoshima M, Nishimura S) / Status : Reviewed
• Structural analysis of trisialylated biantennary glycans isolated from mouse serum transferrin. Characterization of the sequence Neu5Gc(alpha 2-3)Gal(beta 1-3)[Neu5Gc(alpha 2-6)]GlcNAc(beta 1-2)Man. (2000 - Coddeville B, Regoeczi E, Strecker G, Plancke Y, Spik G) / Status : Reviewed
• Structural analysis of murine zona pellucida glycans. Evidence for the expression of core 2-type O-glycans and the Sd(a) antigen. (2000 - Easton RL, Patankar MS, Lattanzio FA, Leaven TH, Morris HR, Clark GF, Dell A) / Status : Reviewed
• Variable domain-linked oligosaccharides of a human monoclonal IgG: structure and influence on antigen binding. (1999 - Leibiger H, Wstner D, Stigler R, Marx U) / Status : Reviewed
• Structures of the N-linked oligosaccharides on porcine plasma vitronectin. (1993 - Yoneda A, Ogawa H, Matsumoto I, Ishizuka I, Hase S, Seno N) / Status : Reviewed
• The N- and O-linked carbohydrate chains of human, bovine and porcine plasminogen. Species specificity in relation to sialylation and fucosylation patterns. (1988 - Marti T, Schaller J, Rickli E, Schmid K, Kamerling J, Gerwig G, van Halbeek H, Vliegenthart J) / Status : Reviewed

Reported glycosite

• Alpha-2-HS-glycoprotein / Homo sapiens
  •        Asn-176
• CD59 glycoprotein / Homo sapiens
  •        Asn-43
• Kininogen-1 / Homo sapiens
  •        Asn-294
• Prostaglandin-h2 d-isomerase / Homo sapiens
  •        Asn-78
• Uromodulin / Homo sapiens
  •        Asn-513
• Plasminogen / Bos taurus
  •        Asn-315
• Immunoglobulin gamma-1 lambda antibody (cbga1) / Hybrid - homo sapiens/mus musculus
  •        Undefined site
• Alpha-1-acid glycoprotein 1 / Mus musculus
  •        Asn-76
• Alpha-1-antitrypsin 1-2 / Mus musculus
  •        Asn-64
  •        Asn-101
• Alpha-2-hs-glycoprotein / Mus musculus
  •        Asn-99
• Beta-2-glycoprotein 1 / Mus musculus
  •        Asn-162
• Ceruloplasmin / Mus musculus
  •        Asn-138
• Complement c4-b / Mus musculus
  •        Asn-1387
• Complement factor h / Mus musculus
  •        Asn-1061
• Immunoglobulin gamma-2 chain c region / Mus musculus
  •        Asn-176
• Immunoglobulin gamma-2b chain c region / Mus musculus
  •        Asn-185
• Immunoglobulin j chain / Mus musculus
  •        Asn-70
• Inter-alpha-trypsin inhibitor heavy chain h3 / Mus musculus
  •        Asn-580
• Pregnancy zone protein / Mus musculus
  •        Asn-1003
• Serotransferrin / Mus musculus
  •        Undefined site
  •        Asn-513
• Zona pellucida sperm-binding protein matrix / Mus musculus
  •        Undefined site
• Plasminogen / Sus scrofa
  •        Asn-289
• Vitronectin / Sus scrofa
  •        Undefined site

Mass spectrometry observed peptide

• TAVNCSSDFDACLITK (16aa)
  •    P13987    Asn-43     CD59 glycoprotein / Homo sapiens
• SVVAPATDGGLNLTSTFLRKNQCETR (26aa)
  •    P41222    Asn-78     Prostaglandin-h2 d-isomerase / Homo sapiens
• SVVAPATDGGLNLTSTFLR (19aa)
  •    P41222    Asn-78     Prostaglandin-h2 d-isomerase / Homo sapiens
• AALAAFNAQNNGSNFQLEEISR (22aa)
  •    P02765    Asn-176     Alpha-2-HS-glycoprotein / Homo sapiens
• LNAENNATFYFK (12aa)
  •    P01042    Asn-294     Kininogen-1 / Homo sapiens
• FALLMTNCYATPSSNATDPLK (21aa)
  •    P07911    Asn-513     Uromodulin / Homo sapiens