Hex:4 HexNAc:4 dHex:2 NeuAc:1

Taxonomy

• Homo sapiens (Human)

Protein

• Acid ceramidase / Homo sapiens    Q13510
• Alpha-1-antitrypsin / Homo sapiens    P01009
• Alpha-2-HS-glycoprotein / Homo sapiens    P02765
• Asporin / Homo sapiens    Q9BXN1
• Beta-2-glycoprotein 1 / Homo sapiens    P02749
• Beta-glucuronidase / Homo sapiens    P08236
• Biglycan / Homo sapiens    P21810
• CD44 antigen / Homo sapiens    P16070
• Ceruloplasmin / Homo sapiens    P00450
• Collagen alpha-1(XII) chain / Homo sapiens    Q99715
• Collagen alpha-2(VI) chain / Homo sapiens    P12110
• Complement factor h / Homo sapiens    P08603
• Decorin / Homo sapiens    P07585
• Desmocollin-2 / Homo sapiens    Q02487
• Dipeptidyl peptidase 1 / Homo sapiens    P53634
• Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B / Homo sapiens    Q8TCJ2
• Endogenous retrovirus group 3 member 1 Env polyprotein / Homo sapiens    Q14264
• Fibrinogen beta chain / Homo sapiens    P02675
• Fibronectin / Homo sapiens    P02751
• Galectin-3-binding protein / Homo sapiens    Q08380
• Gamma-glutamyl hydrolase / Homo sapiens    Q92820
• GDNF family receptor alpha-1 / Homo sapiens    P56159
• Glucosylceramidase / Homo sapiens    P04062
• Haptoglobin / Homo sapiens    P00738
• Hemopexin / Homo sapiens    P02790
• Histidine-rich glycoprotein / Homo sapiens    P04196
• Immunoglobulin alpha (secretory) / Homo sapiens    P01876    P01877
• Immunoglobulin heavy constant alpha 2 / Homo sapiens    P01877
• Integrin alpha-2 / Homo sapiens    P17301
• Integrin alpha-V / Homo sapiens    P06756
• Inter-alpha-trypsin inhibitor heavy chain h2 / Homo sapiens    P19823
• Lactotransferrin / Homo sapiens    P02788
• Lumican / Homo sapiens    P51884
• Lysosome membrane protein 2 / Homo sapiens    Q14108
• Lysosome-associated membrane glycoprotein 1 / Homo sapiens    P11279
• Mammaglobin-A / Homo sapiens    Q13296
• Membrane-bound transcription factor site-1 protease / Homo sapiens    Q14703
• Olfactomedin-like protein 3 / Homo sapiens    Q9NRN5
• Periostin / Homo sapiens    Q15063
• Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 / Homo sapiens    Q02809
• Prolactin-inducible protein / Homo sapiens    P12273
• Prosaposin / Homo sapiens    P07602
• Prostaglandin-h2 d-isomerase / Homo sapiens    P41222
• Receptor tyrosine-protein kinase erbB-2 / Homo sapiens    P04626
• Serotransferrin / Homo sapiens    P02787
• Target of Nesh-SH3 / Homo sapiens    Q7Z7G0
• Translocon-associated protein subunit alpha / Homo sapiens    P43307
• Uncharacterized protein from Granulocyte / Homo sapiens
• UPF0577 protein KIAA1324 / Homo sapiens    Q6UXG2
• Uromodulin / Homo sapiens    P07911
• Versican core protein / Homo sapiens    P13611
• Villin-1 / Homo sapiens    P09327
• Zinc transporter ZIP6 / Homo sapiens    Q13433
• Zinc-alpha-2-glycoprotein / Homo sapiens    P25311
• Zymogen granule protein 16 homolog B / Homo sapiens    Q96DA0

Source

• Blood Plasma (UBERON_0001969)  
• Blood Serum (UBERON_0001977)  
• Mammary Gland (UBERON_0001911)  
• Milk (UBERON_0001913)  
• Urine (UBERON_0001088)  
• Granulocyte (CL_0000094)  

Reported structure

• N-Linked / Complex / Structure 183
• N-Linked / Complex / Structure 1854
• O-Linked / Core 2 / Fuc(a1-2)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-3)]GalNAc
• O-Linked / Core 2 / Fuc(a1-4)[Gal(b1-3)]GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-3)]GalNAc
• O-Linked / Core 2 / Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-3)]GalNAc+"+ 2 x Fuc(a1-3)"

Composition

• Hex:4 HexNAc:4 dHex:2 NeuAc:1 (avg mass : 2062.9088 )

Disease

• Cancer, breast (DOID:1612)
• Prostate cancer (DOID:10283)

Reference

• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed
• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• Large-scale intact glycopeptide identification by Mascot database search (2018 - Ravi Chand Bollineni, Christian Jeffrey Koehler, Randi Elin Gislefoss, Jan Haug Anonsen, Bernd Thiede) / Status : Unreviewed
• Exploring site-specific N-glycosylation microheterogeneity of haptoglobin using glycopeptide CID tandem mass spectra and glycan database search (2013 - Chandler KB1, Pompach P, Goldman R, Edwards N.) / Status : Reviewed
• Automated assignments of N- and O-site specific glycosylation with extensive glycan heterogeneity of glycoprotein mixtures (2013 - Strum JS1, Nwosu CC, Hua S, Kronewitter SR, Seipert RR, Bachelor RJ, An HJ, Lebrilla CB) / Status : Reviewed
• Primary structure of twenty three neutral and monosialylated oligosaccharides O-glycosidically linked to the human secretory immunoglobulin A hinge region determined by a combination of permethylation analysis and 400-MHz 1H-NMR spectroscopy. (1989 - Pierce-Cretel A, Decottignies J, Wieruszeski J, Strecker G, Montreuil J, Spik G) / Status : Reviewed
• Structures of O-linked oligosaccharides isolated from normal granulocytes, chronic myelogenous leukemia cells, and acute myelogenous leukemia cells. (1986 - Fukuda M, Carlsson S, Klock J, Dell A) / Status : Reviewed

Reported glycosite

• Acid ceramidase / Homo sapiens
  •        Asn-286
• Alpha-1-antitrypsin / Homo sapiens
  •        Asn-271
• Alpha-2-HS-glycoprotein / Homo sapiens
  •        Asn-156
• Asporin / Homo sapiens
  •        Asn-282
• Beta-2-glycoprotein 1 / Homo sapiens
  •        Asn-253
• Beta-glucuronidase / Homo sapiens
  •        Asn-173
  •        Asn-272
• Biglycan / Homo sapiens
  •        Asn-270
  •        Asn-311
• CD44 antigen / Homo sapiens
  •        Asn-57
• Ceruloplasmin / Homo sapiens
  •        Ser-360
• Collagen alpha-1(XII) chain / Homo sapiens
  •        Asn-2679
• Collagen alpha-2(VI) chain / Homo sapiens
  •        Asn-785
• Complement factor h / Homo sapiens
  •        Asn-911
• Decorin / Homo sapiens
  •        Asn-262
• Desmocollin-2 / Homo sapiens
  •        Asn-392
• Dipeptidyl peptidase 1 / Homo sapiens
  •        Asn-53
• Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B / Homo sapiens
  •        Asn-616
• Endogenous retrovirus group 3 member 1 Env polyprotein / Homo sapiens
  •        Asn-105
• Fibrinogen beta chain / Homo sapiens
  •        Asn-394
• Fibronectin / Homo sapiens
  •        Asn-528
• Galectin-3-binding protein / Homo sapiens
  •        Asn-69
• Gamma-glutamyl hydrolase / Homo sapiens
  •        Asn-307
• GDNF family receptor alpha-1 / Homo sapiens
  •        Asn-59
• Glucosylceramidase / Homo sapiens
  •        Asn-185
• Haptoglobin / Homo sapiens
  •        Asn-207
• Hemopexin / Homo sapiens
  •        Asn-64
  •        Asn-453
• Histidine-rich glycoprotein / Homo sapiens
  •        Asn-125
• Immunoglobulin alpha (secretory) / Homo sapiens
  •        Undefined site
• Immunoglobulin heavy constant alpha 2 / Homo sapiens
  •        Asn-205
• Integrin alpha-2 / Homo sapiens
  •        Asn-1057
• Integrin alpha-V / Homo sapiens
  •        Asn-615
• Inter-alpha-trypsin inhibitor heavy chain h2 / Homo sapiens
  •        Asn-118
• Lactotransferrin / Homo sapiens
  •        Asn-642
• Lumican / Homo sapiens
  •        Asn-127
• Lysosome membrane protein 2 / Homo sapiens
  •        Asn-325
• Lysosome-associated membrane glycoprotein 1 / Homo sapiens
  •        Asn-249
  •        Asn-261
• Mammaglobin-A / Homo sapiens
  •        Asn-53
• Membrane-bound transcription factor site-1 protease / Homo sapiens
  •        Asn-148
• Olfactomedin-like protein 3 / Homo sapiens
  •        Asn-177
• Periostin / Homo sapiens
  •        Asn-599
• Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 / Homo sapiens
  •        Asn-538
• Prolactin-inducible protein / Homo sapiens
  •        Asn-105
• Prosaposin / Homo sapiens
  •        Asn-80
• Prostaglandin-h2 d-isomerase / Homo sapiens
  •        Ser-67
  •        Asn-78
• Receptor tyrosine-protein kinase erbB-2 / Homo sapiens
  •        Ser-998
• Serotransferrin / Homo sapiens
  •        Asn-432
  •        Asn-630
• Target of Nesh-SH3 / Homo sapiens
  •        Asn-259
• Translocon-associated protein subunit alpha / Homo sapiens
  •        Asn-136
• Uncharacterized protein from Granulocyte / Homo sapiens
  •        Undefined site
• UPF0577 protein KIAA1324 / Homo sapiens
  •        Asn-717
• Uromodulin / Homo sapiens
  •        Thr-504
  •        Ser-511
  •        Asn-513
• Versican core protein / Homo sapiens
  •        Asn-330
• Villin-1 / Homo sapiens
  •        Asn-526
• Zinc transporter ZIP6 / Homo sapiens
  •        Asn-266
• Zinc-alpha-2-glycoprotein / Homo sapiens
  •        Asn-128
• Zymogen granule protein 16 homolog B / Homo sapiens
  •        Asn-197

Mass spectrometry observed peptide

• DVNCSVMGPQEK (12aa)
  •    P53634    Asn-53
• ELLQEFIDDNATTNAIDELK (20aa)
  •    Q13296    Asn-53
• AFNSTLPTMAQMEK (14aa)
  •    P16070    Asn-57
• ETNFSIASGIEAK (13aa)
  •    P56159    Asn-59
• CSDGWSFDATTLDDNGTMLFFK (22aa)
  •    P02790    Asn-64
• SVVAPATDGGLNLTSTFLR (19aa)
  •    P41222    Asn-78
• SVVAPATDGGLNLTSTFLR (19aa)
  •    P41222    Ser-67
• ALGFENATQALGR (13aa)
  •    Q08380    Asn-69
• DNATEEEILVYLEK (14aa)
  •    P07602    Asn-80
• TFYWDFYTNR (10aa)
  •    P12273    Asn-105
• EGDLLNQTK (9aa)
  •    Q14264    Asn-105
• GAFISNFSMTVDGK (14aa)
  •    P19823    Asn-118
• LHINHNNLTESVGPLPK (17aa)
  •    P51884    Asn-127
• VIDFNCTTSSVSSAIANTK (19aa)
  •    P04196    Asn-125
• FGCEIENNR (9aa)
  •    P25311    Asn-128
• YPQDYQFYIQNFTAIPINTVVPPQR (25aa)
  •    P43307    Asn-136
• YAESDPTVPCNETR (14aa)
  •    Q14703    Asn-148
• VCQDCPIIAPINDTR (15aa)
  •    P02765    Asn-156
• ITIAINNTLTPTTLPPGTIQYLTDTSK (27aa)
  •    P08236    Asn-173
• IYVIDGTQNDTAFVFPR (17aa)
  •    Q9NRN5    Asn-177
• TYTYADTPDDFQIHNFSIPEEDTK (24aa)
  •    P04062    Asn-185
• SIGFEWNYPLEEPTTEPPVNLTYSANSPVGR (31aa)
  •    Q96DA0    Asn-197
• TPLTANITK (9aa)
  •    P01877    Asn-205
• KDNTTVTR (8aa)
  •    P11279    Asn-249
• IGNWSAMPSCK (11aa)
  •    P02749    Asn-253
• QVIQNVTHK (9aa)
  •    Q7Z7G0    Asn-259
• IININPNK (8aa)
  •    P11279    Asn-261
• IGISFNSISAVDNGSIANTPHIR (23aa)
  •    P07585    Asn-262
• NTNENPQECFNASK (14aa)
  •    Q13433    Asn-266
• MIENGSISFIPTIR (14aa)
  •    P21810    Asn-270
• YIGNATAIFFIPDEGK (16aa)
  •    P01009    Asn-271
• VVANGTGTQGQIK (13aa)
  •    P08236    Asn-272
• ITDIENGSIANIPR (14aa)
  •    Q9BXN1    Asn-282
• IIAPAYFIIGGNQSGEGCVITR (22aa)
  •    Q13510    Asn-286
• ALIYQFSPIYTGNISSFQQ (19aa)
  •    Q92820    Asn-307
• IIQVVYIHSNNITK (14aa)
  •    P21810    Asn-311
• CLGSGVLNVSICK (13aa)
  •    Q14108    Asn-325
• FENQTGFPPPDSR (13aa)
  •    P13611    Asn-330
• AGLQAFFQVQECNKSSSK (18aa)
  •    P00450    Ser-360
• ANYTILK (7aa)
  •    Q02487    Asn-392
• GTAGNAIMDGASQIMGENR (19aa)
  •    P02675    Asn-394
• CGIVPVIAENYNK (13aa)
  •    P02787    Asn-432
• AIPQPQNVTSIIGCTH (16aa)
  •    P02790    Asn-453
• FALLMTNCYATPSSNATDPLKYFIIQDR (28aa)
  •    P07911    Asn-513
• FALLMTNCYATPSSNATDPLKYFIIQDR (28aa)
  •    P07911    Thr-504
• FALLMTNCYATPSSNATDPLK (21aa)
  •    P07911    Asn-513
• FALLMTNCYATPSSNATDPLK (21aa)
  •    P07911    Ser-511
• LFQVQGTGANNTK (13aa)
  •    P09327    Asn-526
• DQCIVDDITYNVNDTFHK (18aa)
  •    P02751    Asn-528
• YIHQNYTK (8aa)
  •    Q02809    Asn-538
• EVNDTLLVNELK (12aa)
  •    Q15063    Asn-599
• TAADTTGIQPIINQFTPANISR (22aa)
  •    P06756    Asn-615
• VMSWWDYGYQIAGMANR (17aa)
  •    Q8TCJ2    Asn-616
• QQQHIFGSNVTDCSGNFCIFR (21aa)
  •    P02787    Asn-630
• MSVCTDNVTDLR (12aa)
  •    Q6UXG2    Asn-717
• NMTLFSDLVAEK (12aa)
  •    P12110    Asn-785
• ISEENETTCYMGK (13aa)
  •    P08603    Asn-911
• DPQRFVVIQNEDLGPASPLDSTFYR (25aa)
  •    P04626    Ser-998
• TASCSNVTCWIK (12aa)
  •    P17301    Asn-1057
• EAGNITTDGYEIIGK (15aa)
  •    Q99715    Asn-2679