Hex:5 HexNAc:4 NeuAc:3

Taxonomy

• Homo sapiens (Human)
• Bos taurus (Bovine)
• Mus musculus (House mouse)
• Ovis aries (Sheep)
• Rattus norvegicus (Norway rat)

Protein

• Alpha-1-acid glycoprotein 1 / Homo sapiens    P02763
• Alpha-1-antitrypsin / Homo sapiens    P01009
• Serotransferrin / Homo sapiens    P02787
• Alpha-1-acid glycoprotein / Bos taurus    Q3SZR3
• Alpha-2-hs-glycoprotein / Bos taurus    P12763
• Coagulation factor IX / Bos taurus    P00741
• Coagulation factor x / Bos taurus    P00743
• Prothrombin / Bos taurus    P00735
• Major urinary protein / Mus musculus    
• Alpha-1-acid glycoprotein / Ovis aries    W5P7S6
• Serotransferrin / Rattus norvegicus    P12346
• T-kininogen / Rattus norvegicus    P08932    P01048
• Uncharacterized protein / Rattus norvegicus    

Source

• Blood Plasma (UBERON_0001969)  
• Blood Serum (UBERON_0001977)  
• Urine (UBERON_0001088)  
• Hepatocyte (CL_0000182)  

Reported structure

• N-Linked / Complex / Gal(b1-4)GlcNAc(?1-?)Man(a1-3)[Gal(b1-4)GlcNAc(?1-?)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ 3 x NeuAc(a2-?)"
• N-Linked / Complex / NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GlcNAc(b1-2)Man(a1-3)[NeuAc(a2-3)Gal(b1-3)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / Complex / NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GlcNAc(b1-2)Man(a1-3)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)[NeuAc(a2-3)]GlcNAc(b1-2)Man(a1-?)[NeuAc(a2-6)Gal(b1-?)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / Complex / NeuAc(a2-?)Gal(b1-3)[NeuAc(a2-6)]GlcNAc(b1-2)Man(a1-3)[NeuAc(a2-?)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / Complex / Structure 10705
• N-Linked / Complex / Structure 10706
• N-Linked / Complex / Structure 10720
• N-Linked / Complex / Structure 10721
• N-Linked / Complex / Structure 10786

Composition

• Hex:5 HexNAc:4 NeuAc:3 (avg mass : 2515.281 )

Disease

• Familial hepatic adenoma (DOID:111366)

Reference

• Aberrant sialylation in a patient with a HNF1α variant and liver adenomatosis (2021 - Luisa Sturiale, Marie-Cécile Nassogne, Angelo Palmigiano, Angela Messina, Immacolata Speciale, Rosangela Artuso, Gaetano Bertino, Nicole Revencu, Xavier Stephénne, Cristina De Castro, Gert Matthijs, Rita Barone, Jaak Jaeken, Domenico Garozzo) / Status : Reviewed
• Glycosylated major urinary protein of the house mouse: characterization of its N-linked oligosaccharides. (2000 - Mechref Y, Zidek L, Ma W, Novotny M) / Status : Reviewed
• Structural determination of N-linked carbohydrates by matrix-assisted laser desorption/ionization-mass spectrometry following enzymatic release within sodium dodecyl sulfate-polyacrylamide electrophoresis gels: application to species-specific glycosylation of alpha1-acid glycoprotein. (1998 - Kuster B, Hunter A, Wheeler S, Dwek R, Harvey D) / Status : Reviewed
• Structural differences between complex-type Asn-linked glycan chains of glycoproteins in rat hepatocytes and Zajdela hepatoma cells. (1995 - Goulut-Chassaing C, Bourrillon R) / Status : Reviewed
• Comparative study of asparagine-linked glycans of plasma T-kininogen in normal rats and during acute inflammation. (1992 - Baussant T, Alonso C, Wieruszeski J, Strecker G, Montreuil J, Alhenc-Gelas F, Michalski J) / Status : Reviewed
• Carbohydrate microheterogeneity of rat serotransferrin. Determination of glycan primary structures and characterization of a new type of trisialylated diantennary glycan. (1991 - Spik G, Coddeville B, Strecker G, Montreuil J, Regoeczi E, Chindemi P, Rudolph J) / Status : Reviewed
• The structures of the carbohydrate moieties of bovine blood coagulation factor IX (Christmas factor). (1983 - Mizuochi T, Taniguchi T, Fujikawa K, Titani K, Kobata A) / Status : Reviewed
• The structures of the carbohydrate moieties of bovine blood coagulation factor X. (1980 - Mizuochi T, Yamashita K, Fujikawa K, Titani K, Kobata A) / Status : Reviewed
• The carbohydrate of bovine prothrombin. Occurrence of Galb1-3GlcNAc grouping in asparagine-linked sugar chains. (1979 - Mizuochi T, Yamashita K, Fujikawa K, Kisiel W, Kobata A) / Status : Reviewed

Reported glycosite

• Alpha-1-acid glycoprotein 1 / Homo sapiens
  •        Undefined site
• Alpha-1-antitrypsin / Homo sapiens
  •        Undefined site
• Serotransferrin / Homo sapiens
  •        Undefined site
• Alpha-1-acid glycoprotein / Bos taurus
  •        Undefined site
• Alpha-2-hs-glycoprotein / Bos taurus
  •        Undefined site
• Coagulation factor IX / Bos taurus
  •        Undefined site
• Coagulation factor x / Bos taurus
  •        Asn-218
• Prothrombin / Bos taurus
  •        Undefined site
• Major urinary protein / Mus musculus
  •        Undefined site
• Alpha-1-acid glycoprotein / Ovis aries
  •        Undefined site
• Serotransferrin / Rattus norvegicus
  •        Undefined site
• T-kininogen / Rattus norvegicus
  •        Undefined site
• Uncharacterized protein / Rattus norvegicus
  •        Undefined site

Mass spectrometry observed peptide