GlyConnect

taxonomy (3) protein (5) source (3) structure (1) composition (1) disease (2) reference (3) site (7) peptide (6)

Taxonomy

Protein

Source

Reported structure

N-Linked / Complex / Gal(b1-4)GlcNAc(?1-?)[Gal(b1-4)GlcNAc(?1-?)]Man(a1-?)[Gal(b1-4)GlcNAc(?1-?)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ Gal(b1-4)GlcNAc(?1-?) + 3 x NeuAc(a2-?) + NeuGc(a2-?)"

Composition

Hex:7 HexNAc:6 NeuAc:3 NeuGc:1 (avg mass : 3553.2131 )

Disease

COVID-19 (DOID:0080600)
Prostate cancer (DOID:10283)

Reference

Deducing the N- and O- glycosylation profile of the spike protein of novel coronavirus SARS-CoV-2 (2020 - Asif Shajahan, Nitin T. Supekar, Anne S. Gleinich, Parastoo Azadi) / Status : Unreviewed
Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
Structural determination of N-linked carbohydrates by matrix-assisted laser desorption/ionization-mass spectrometry following enzymatic release within sodium dodecyl sulfate-polyacrylamide electrophoresis gels: application to species-specific glycosylation of alpha1-acid glycoprotein. (1998 - Kuster B, Hunter A, Wheeler S, Dwek R, Harvey D) / Status : Reviewed

Reported glycosite

CD59 glycoprotein / Homo sapiens
- Asn-43
Icos ligand / Homo sapiens
- Asn-102
Uromodulin / Homo sapiens
- Asn-322
Alpha-1-acid glycoprotein / Ovis aries
- Undefined site
Recombinant Spike glycoprotein (HEK293) - DRAFT DATA / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
- Asn-149
- Asn-282
- Asn-1074

Mass spectrometry observed peptide

- N-Linked / Complex (avg mass : 3553.2131)

- Hex:7 HexNAc:6 NeuAc:3 NeuGc:1 / N-Linked (avg mass : 3553.2131)