Hex:4 HexNAc:8

Taxonomy

• Homo sapiens (Human)
• Mus musculus (House mouse)
• Gallus gallus (Chicken)
• Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)

Protein

• Lactotransferrin / Homo sapiens    P02788
• Polymeric immunoglobulin receptor / Homo sapiens    P01833
• Uromodulin / Homo sapiens    P07911
• Lysosome-associated membrane glycoprotein 1 / Mus musculus    P11438
• Sodium/potassium-transporting ATPase subunit beta-2 / Mus musculus    P14231
• Ovalbumin / Gallus gallus    P01012
• Ovomucoid / Gallus gallus    P01005
• Riboflavin-binding protein / Gallus gallus    P02752
• Uncharacterized protein from Egg Cell / Gallus gallus    
• Recombinant Spike glycoprotein (HEK293) / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)    P0DTC2

Source

• Brain (UBERON_0000955)  
• Milk (UBERON_0001913)  
• Urine (UBERON_0001088)  
• HEK293 (CVCL_0045)  
• Egg Cell  

Reported structure

• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-2)[GlcNAc(b1-4)][GlcNAc(b1-6)]Man(a1-6)[GlcNAc(b1-2)[GlcNAc(b1-4)]Man(a1-3)][GlcNAc(b1-4)]Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-4)[GlcNAc(b1-2)][GlcNAc(b1-6)]Man(a1-6)[GlcNAc(b1-2)[GlcNAc(b1-4)]Man(a1-3)][GlcNAc(b1-4)]Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-4)[GlcNAc(b1-2)]Man(a1-3)[GlcNAc(b1-2)[GlcNAc(b1-4)][GlcNAc(b1-6)]Man(a1-6)][GlcNAc(b1-4)]Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / Complex / GlcNAc(b1-2)[GlcNAc(b1-4)][GlcNAc(b1-6)]Man(a1-6)[GlcNAc(b1-2)[GlcNAc(b1-4)]Man(a1-3)][GlcNAc(b1-4)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ Gal(b1-4)"
• N-Linked / Complex / Structure 9473

Composition

• Hex:4 HexNAc:8 (avg mass : 2292.1449 )

Disease

• COVID-19 (DOID:0080600)
• Prostate cancer (DOID:10283)

Reference

• Site-specific N-glycosylation Characterization of Recombinant SARS-CoV-2 Spike Proteins using High-Resolution Mass Spectrometry (2020 - Yong Zhang, Wanjun Zhao, Yonghong Mao, Shisheng Wang, Yi Zhong, Tao Su, Meng Gong, Xiaofeng Lu, Jingqiu Cheng, Hao Yang) / Status : Unreviewed
• Quantitative Longitudinal Inventory of the N-Glycoproteome of Human Milk from a Single Donor Reveals the Highly Variable Repertoire and Dynamic Site-Specific Changes (2020 - Jing Zhu, Yu-Hsien Lin, Kelly A Dingess, Marko Mank, Bernd Stahl, Albert J R Heck) / Status : Reviewed
• Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis (2019 - Nicholas M. Riley, Alexander S. Hebert, Michael S. Westphall & Joshua J. Coon ) / Status : Unreviewed
• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• Composition of the N-linked carbohydrates from ovalbumin and co-purified glycoproteins. (2000 - Harvey D, Wing D, Kuster B, Wilson I) / Status : Reviewed
• Structural study of the carbohydrate moiety of hen ovomucoid. Occurrence of a series of pentanntennary complex-type asparagine-linked sugar chains (1982 - Yamashita K, Kamerling JP, Kobata A) / Status : Reviewed

Reported glycosite

• Lactotransferrin / Homo sapiens
  •        Asn-156
• Polymeric immunoglobulin receptor / Homo sapiens
  •        Asn-499
• Uromodulin / Homo sapiens
  •        Asn-322
  •        Asn-513
• Lysosome-associated membrane glycoprotein 1 / Mus musculus
  •        Asn-78
• Sodium/potassium-transporting ATPase subunit beta-2 / Mus musculus
  •        Asn-193
• Ovalbumin / Gallus gallus
  •        Undefined site
• Ovomucoid / Gallus gallus
  •        Undefined site
• Riboflavin-binding protein / Gallus gallus
  •        Undefined site
• Uncharacterized protein from Egg Cell / Gallus gallus
  •        Undefined site
• Recombinant Spike glycoprotein (HEK293) / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
  •        Asn-234
  •        Asn-657

Mass spectrometry observed peptide

• NGSSCGKENVSDPSLTITFGR (21aa)
  •    P11438    Asn-78
• RRTAGWNVPIGTLRPFLNWTGPPEPIEAAVARF (33aa)
  •    P02788    Asn-156
• VINFYAGANQSMNVTCVGK (19aa)
  •    P14231    Asn-193
• PLVDLPIGINITR (13aa)
  •    P0DTC2    Asn-234
• QDFNITDISLLEHR (14aa)
  •    P07911    Asn-322
• KWNNTGCQALPSQDEGPSKA (20aa)
  •    P01833    Asn-499
• FALLMTNCYATPSSNATDPLK (21aa)
  •    P07911    Asn-513
• AGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPR (36aa)
  •    P0DTC2    Asn-657