GlyConnect

taxonomy (10) protein (46) source (37) structure (22) composition (1) disease (14) reference (47) site (50) peptide (4)

Taxonomy

Protein

Source

Reported structure

Composition

Hex:2 HexNAc:2 NeuAc:1 (avg mass : 1039.948 )

Disease

Reference

Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
Identification of protein O-glycosylation site and corresponding glycans using liquid chromatography-tandem mass spectrometry via mapping accurate mass and retention time shift (2014 - Huang LJ, Lin JH, Tsai JH, Chu YY, Chen YW, Chen SL, Chen SH) / Status : Reviewed
Automated assignments of N- and O-site specific glycosylation with extensive glycan heterogeneity of glycoprotein mixtures (2013 - Strum JS1, Nwosu CC, Hua S, Kronewitter SR, Seipert RR, Bachelor RJ, An HJ, Lebrilla CB) / Status : Reviewed
Murine and human zona pellucida 3 derived from mouse eggs express identical O-glycans. (2003 - Dell A, Chalabi S, Easton RL, Haslam SM, Sutton-Smith M, Patankar MS, Lattanzio F, Panico M, Morris HR, Clark GF) / Status : Reviewed
Recombinant MUC1 probe authentically reflects cell-specific O-glycosylation profiles of endogenous breast cancer mucin. High density and prevalent core 2-based glycosylation. (2002 - Muller S, Hanisch FG) / Status : Reviewed
Neutralization of pH in the Golgi apparatus causes redistribution of glycosyltransferases and changes in the O-glycosylation of mucins. (2001 - Axelsson M, Karlsson N, Steel D, Ouwendijk J, Nilsson T, Hansson G) / Status : Reviewed
In vivo glycosylation of mucin tandem repeats (2001 - Silverman, Parry, Sutton-Smith, Burdick, McDermott, Reid, Batra, Morris, Hollingsworth, Dell, Harris) / Status : Reviewed
O-glycan analysis of natural human neutrophil gelatinase B using a combination of normal phase-HPLC and online tandem mass spectrometry: implications for the domain organization of the enzyme. (2000 - Mattu T, Royle L, Langridge J, Wormald M, Van den Steen P, Van Damme J, Opdenakker G, Harvey D, Dwek R, Rudd P) / Status : Reviewed
Structural analysis of murine zona pellucida glycans. Evidence for the expression of core 2-type O-glycans and the Sd(a) antigen. (2000 - Easton RL, Patankar MS, Lattanzio FA, Leaven TH, Morris HR, Clark GF, Dell A) / Status : Reviewed
Structural analysis of 20 oligosaccharide-alditols released from the jelly coat of Rana palustris eggs by reductive beta-elimination characterization of the polymerized sequence [Gal(beta1, 3)GalNAc(alpha1-4)]n. (1999 - Maes E, Florea D, Coppin A, Strecker G) / Status : Reviewed
High prevalence of 2-mono- and 2,6-di-substituted manol-terminating sequences among O-glycans released from brain glycopeptides by reductive alkaline hydrolysis. (1999 - Chai W, Yuen C, Kogelberg H, Carruthers R, Margolis R, Feizi T, Lawson A) / Status : Reviewed
Purification and characterization of the MUC1 mucin-type glycoprotein, epitectin, from human urine: structures of the major oligosaccharide alditols. (1998 - Bhavanandan V, Zhu Q, Yamakami K, Dilulio N, Nair S, Capon C, Lemoine J, Fournet B) / Status : Reviewed
Structural characterisation of N-linked and O-linked oligosaccharides derived from interferon-alpha2b and interferon-alpha14c produced by Sendai-virus-induced human peripheral blood leukocytes (1998 - Nyman, Kalkkinen, Tolo, Helin) / Status : Reviewed
Human low-molecular-weight salivary mucin expresses the sialyl lewisx determinant and has L-selectin ligand activity. (1998 - Prakobphol A, Thomsson K, Hansson G, Rosen S, Singer M, Phillips N, Medzihradszky K, Burlingame A, Leffler H, Fisher S) / Status : Reviewed
Structure of the O-linked oligosaccharides from a major thyroid cell surface glycoprotein. (1997 - Edge A, Spiro R) / Status : Reviewed
Structures of the O-glycans on P-selectin glycoprotein ligand-1 from HL-60 cells. (1996 - Wilkins P, McEver R, Cummings R) / Status : Reviewed
Characterization of four monosialo and a novel disialo Asn N-glycosides from the urine of a patient with aspartylglycosaminuria. (1995 - Irie F, Murakoshi H, Suzuki T, Suzuki Y, Kon K, Ando S, Yoshida K, Hirabayashi Y) / Status : Reviewed
Sialylation and sulfation of the carbohydrate chains in respiratory mucins from a patient with cystic fibrosis. (1994 - Lo-Guidice J, Wieruszeski J, Lemoine J, Verbert A, Roussel P, Lamblin G) / Status : Reviewed
Structure of the O-linked carbohydrate chains of porcine zona pellucida glycoproteins. (1994 - Hokke C, Damm J, Penninkhof B, Aitken R, Kamerling J, Vliegenthart J) / Status : Reviewed
Structures of monosialyl oligosaccharides isolated from the respiratory mucins of a non-secretor (O, Lea+b-) patient suffering from chronic bronchitis. Characterization of a novel type of mucin carbohydrate core structure. (1994 - van Halbeek H, Strang A, Lhermitte M, Rahmoune H, Lamblin G, Roussel P) / Status : Reviewed
Characterization of two different glycosylated domains from the insoluble mucin complex of rat small intestine. (1993 - Carlstedt I, Herrmann A, Karlsson H, Sheehan J, Fransson L, Hansson G) / Status : Reviewed
Oligosaccharide structures of mucins secreted by the human colonic cancer cell line CL.16E. (1992 - Capon C, Laboisse C, Wieruszeski J, Maoret J, Augeron C, Fournet B) / Status : Reviewed
The broad diversity of neutral and sialylated oligosaccharides derived from human salivary mucins. (1992 - Klein A, Carnoy C, Wieruszeski J, Strecker G, Strang A, van Halbeek H, Roussel P, Lamblin G) / Status : Reviewed
1H and 13C-NMR assignments for sialylated oligosaccharide-alditols related to mucins. Study of thirteen components from hen ovomucin and swallow nest mucin. (1992 - Strecker G, Wieruszeski J, Cuvillier O, Michalski J, Montreuil J) / Status : Reviewed
Altered O-glycan synthesis in lymphocytes from patients with Wiskott-Aldrich syndrome. (1991 - Piller F, Le Deist F, Weinberg K, Parkman R, Fukuda M) / Status : Reviewed
Structures of acidic O-linked polylactosaminoglycans on human skim milk mucins. (1990 - Hanisch F, Peter-Katalinic J, Egge H, Dabrowski U, Uhlenbruck G) / Status : Reviewed
Structure determination of the major N- and O-linked carbohydrate chains of the beta subunit from equine chorionic gonadotropin. (1990 - Damm J, Hard K, Kamerling J, van Dedem G, Vliegenthart J) / Status : Reviewed
Structures of O-glycosidically linked oligosaccharides isolated from human meconium glycoproteins. (1989 - Capon C, Leroy Y, Wieruszeski J, Ricart G, Strecker G, Montreuil J, Fournet B) / Status : Reviewed
Primary structure of twenty three neutral and monosialylated oligosaccharides O-glycosidically linked to the human secretory immunoglobulin A hinge region determined by a combination of permethylation analysis and 400-MHz 1H-NMR spectroscopy. (1989 - Pierce-Cretel A, Decottignies J, Wieruszeski J, Strecker G, Montreuil J, Spik G) / Status : Reviewed
Isolation and structural characterization of low-molecular-mass monosialyl oligosaccharides derived from respiratory-mucus glycoproteins of a patient suffering from bronchiectasis. (1988 - van Halbeek H, Breg J, Vliegenthart J, Klein A, Lamblin G, Roussel P) / Status : Reviewed
Comparative study of the mucin-type sugar chains of human chorionic gonadotropin present in the urine of patients with trophoblastic diseases and healthy pregnant women. (1988 - Amano J, Nishimura R, Mochizuki M, Kobata A) / Status : Reviewed
Structure of sialyl-oligosaccharides isolated from bronchial mucus glycoproteins of patients (blood group O) suffering from cystic fibrosis. (1987 - Breg J, Van Halbeek H, Vliegenthart J, Lamblin G, Houvenaghel M, Roussel P) / Status : Reviewed
The structure of the O-glycosidic oligosaccharide chains of the major Zajdela hepatoma ascites-cell-membrane glycoprotein. (1986 - Nato F, Goulut C, Bourrillon R, Van Halbeek H, Vliegenthart J) / Status : Reviewed
Structures of O-linked oligosaccharides isolated from normal granulocytes, chronic myelogenous leukemia cells, and acute myelogenous leukemia cells. (1986 - Fukuda M, Carlsson S, Klock J, Dell A) / Status : Reviewed
Structural variations of O-linked oligosaccharides present in leukosialin isolated from erythroid, myeloid, and T-lymphoid cell lines. (1986 - Carlsson S, Sasaki H, Fukuda M) / Status : Reviewed
Structures of O-linked oligosaccharides present in the proteoglycans secreted by human mammary epithelial cells. (1986 - Gowda D, Bhavanandan V, Davidson E) / Status : Reviewed
Primary structures and Lewis blood-group-dependent expression of major sialylated saccharides from mucus glycoproteins of human seminal plasma. (1985 - Hanisch F, Egge H, Peter-Katalini J, Uhlenbruck G, Dienst C, Fangmann R) / Status : Reviewed
Structures of the carbohydrate units of polysialoglycoproteins isolated from the eggs of four species of salmonid fishes. (1985 - Iwasaki M, Inoue S) / Status : Reviewed
Purification and structures of oligosaccharide chains in swine trachea and Cowper's gland mucin glycoproteins. (1984 - Rana SS, Chandrasekaran EV, Kennedy J, Mendicino J) / Status : Reviewed
Structures of the O-linked oligosaccharides of the major cell surface sialoglycoprotein of MAT-B1 and MAT-C1 ascites sublines of the 13762 rat mammary adenocarcinoma. (1984 - Hull S, Laine R, Kaizu T, Rodriguez I, Carraway K) / Status : Reviewed
The carbohydrate moiety of human platelet glycocalicin. (1983 - Tsuji T, Tsunehisa S, Watanabe Y, Yamamoto K, Tohyama H, Osawa T) / Status : Reviewed
A carbohydrate structural variant of MM glycoprotein (glycophorin A). (1983 - Adamany A, Blumenfeld O, Sabo B, McCreary J) / Status : Reviewed
Structure of O-glycosidically linked sugar units from plasma membranes of an ascites hepatoma, AH 66. (1982 - Funakoshi I, Yamashina I) / Status : Reviewed
The chemical structure of neutral and acidic sugar chains obtained from bovine colostrum kappa-casein. (1981 - Saito T, Itoh T, Adachi S, Suzuki T, Usui T) / Status : Reviewed
Structural characterization of a novel acidic oligosaccharide unit derived from cow colostrum kappa-casein. A 500 MHz 1H-NMR study. (1981 - van Halbeek H, Dorland L, Vliegenthart J, Fiat A, Jolls P) / Status : Reviewed
Sialoglycoproteins of human mammary cells: partial characterization of sialoglycopeptides. (1979 - Chandrasekaran E, Davidson E) / Status : Reviewed
Immunochemical and chemical investigations of the structure of glycoprotein fragments obtained from epiglycanin, a glycoprotein at the surface of the TA3-Ha cancer cell. (1975 - Codington J, Linsley K, Jeanlot R) / Status : Reviewed

Reported glycosite

Choriogonadotropin - alpha and beta chains / Homo sapiens
- Undefined site
Coagulation factor IX / Homo sapiens
- Thr-85
- Thr-205
- Thr-215
Glycocalicin / Homo sapiens
- Undefined site
Glycophorin-A / Homo sapiens
- Undefined site
Immunoglobulin alpha (secretory) / Homo sapiens
- Undefined site
Insulin-like growth factor II / Homo sapiens
- Thr-99
Inter-alpha-trypsin inhibitor heavy chain h4 / Homo sapiens
- Thr-725
Interferon alpha-2 / Homo sapiens
- Thr-129
Leukosialin (cd43) / Homo sapiens
- Undefined site
Matrix metalloproteinase-9 / Homo sapiens
- Undefined site
Muc1 fusion protein / Homo sapiens
- Undefined site
Muc1f (delta tr) / Homo sapiens
- Undefined site
Mucin / Homo sapiens
- Undefined site
Mucin - mg2 / Homo sapiens
- Undefined site
Mucin-1 / Homo sapiens
- Undefined site
P-selectin glycoprotein ligand (psgl-1) / Homo sapiens
- Undefined site
Plasma protease c1 inhibitor / Homo sapiens
- Thr-47
Proteoglycan / Homo sapiens
- Undefined site
Recombinant Mucin-1 Muc1f (delta tr) / Homo sapiens
- Undefined site
Recombinant Mucin-1 Muc1f/2tr / Homo sapiens
- Undefined site
Recombinant Mucin-1 Muc1f/4tr / Homo sapiens
- Undefined site
Recombinant Mucin-1 Muc1f/5actr / Homo sapiens
- Undefined site
Recombinant Mucin-1 Muc1f/5btr / Homo sapiens
- Undefined site
Serum albumin / Homo sapiens
- Thr-267
Uncharacterized protein from Granulocyte / Homo sapiens
- Undefined site
Uncharacterized protein from Granulocyte / Homo sapiens
- Undefined site
Uncharacterized protein from Mammary Gland / Homo sapiens
- Undefined site
Uncharacterized protein from Urine / Homo sapiens
- Undefined site
Zona pellucida sperm-binding protein 3 / Homo sapiens
- Undefined site
Alpha-2-hs-glycoprotein / Bos taurus
- Ser-271
- Thr-280
Gp-3 / Bos taurus
- Undefined site
Kappa casein / Bos taurus
- Undefined site
- Thr-152
Choriogonadotropin beta chain / Equus caballus
- Undefined site
Epiglycanin / Mus musculus
- Undefined site
Zona pellucida sperm-binding protein matrix / Mus musculus
- Undefined site
Brain non dialyzable glycopeptide / Oryctolagus cuniculus
- Undefined site
Asgp-1 / Rattus norvegicus
- Undefined site
Major membrane glycoprotein - MII2 / Rattus norvegicus
- Undefined site
Mucin-2 glycopeptide a / Rattus norvegicus
- Undefined site
Mucin-2 glycopeptide b / Rattus norvegicus
- Undefined site
Uncharacterized protein from Cell Membranes / Rattus norvegicus
- Undefined site
Mucin / Sus scrofa
- Undefined site
Uncharacterized porcine zona pellucida glycoprotein / Sus scrofa
- Undefined site
Polysialoglycoprotein (psgp) / Salvelinus leucomaenis pluvius
- Undefined site
Mucin / Rana palustris
- Undefined site
Mucin / Collocalia sp
- Undefined site

Mass spectrometry observed peptide

VATTVISK (8aa)
- P05155 Thr-47
DVSTPPTVLPDNFPR (15aa)
- P01344 Thr-99
VHTECCHGDLLECADDR (17aa)
- P02768 Thr-267
IEETTMTTQTPAPIQAPSAILPLPGQSVER (30aa)
- Q14624 Thr-725

- O-Linked / Core 2 (avg mass : 1039.948)
- O-Linked / Undefined core (avg mass : 1039.948)
- O-Linked / Core 2 (avg mass : 1039.948)
- O-Linked / Core 1 (avg mass : 1039.948)
- O-Linked / Core 1 (avg mass : 1039.948)
- O-Linked / Core 2 (avg mass : 1039.948)
- O-Linked / Core 2 (avg mass : 1039.948)
- O-Linked / Core 2 (avg mass : 1039.948)
- O-Linked / Core 2 (avg mass : 1039.948)
- O-Linked / Core 1 (avg mass : 1039.948)
- O-Linked / No-core (avg mass : 1039.948)
- O-Linked / Core 2 (avg mass : 1039.948)
- O-Linked / Core 1 (avg mass : 1039.948)
- O-Linked / Core 1 (avg mass : 1039.948)
- O-Linked / Core 1 (avg mass : 1039.948)
- N-Linked / No-core (avg mass : 1039.948)
- O-Linked / Core 2 (avg mass : 1039.948)
- O-Linked / Undefined core (avg mass : 1039.948)
- O-Linked / Core 2 (avg mass : 1039.948)
- O-Linked / Core 1 (avg mass : 1039.948)
- N-Linked / No-core (avg mass : 1039.948)
- O-Linked / Undefined core (avg mass : 1039.948)

- Hex:2 HexNAc:2 NeuAc:1 / O-Linked (avg mass : 1039.948)