Hex:2 HexNAc:2 dHex:1 Su:1

Taxonomy

• Homo sapiens (Human)
• Canis familiaris (Dog)
• Macaca radiata (Bonnet macaque)
• Rattus norvegicus (Norway rat)
• Rana arvalis (Moor frog)

Protein

• Mucin-5B / Homo sapiens    Q9HC84
• Mucin-7 / Homo sapiens    Q8TAX7
• Unspecified mucin / Homo sapiens
• Mucin / Canis familiaris
• Mucin / Macaca radiata
• Mucin-2 glycopeptide a / Rattus norvegicus    Q62635
• Mucin / Rana arvalis

Source

• Cervical Mucosa (UBERON_0012248)  
• Pulmonary Mucosa  
• Saliva (UBERON_0001836)  
• Small Intestine (UBERON_0002108)  
• Submandibular Gland (UBERON_0001736)  
• Egg Cell   Jelly Coat  

Reported structure

• O-Linked / Core 1 / Fuc(a1-2)Gal(b1-?)[HSO3(-?)]GlcNAc(b1-6)Gal(b1-3)GalNAc
• O-Linked / Core 1 / HSO3(-3)Gal(b1-3)[Fuc(a1-2)][GlcNAc(b1-6)]Gal(b1-3)GalNAc
• O-Linked / Core 2 / Fuc(a1-2)[Gal(a1-3)]Gal(b1-3)[HSO3(-6)GlcNAc(b1-6)]GalNAc
• O-Linked / Core 2 / Fuc(a1-2)[Gal(b1-3)]Gal(b1-3)[HSO3(-6)GlcNAc(b1-6)]GalNAc
• O-Linked / Core 2 / Fuc(a1-2)Gal(b1-4)[HSO3(-6)]GlcNAc(b1-6)[Gal(b1-3)]GalNAc
• O-Linked / Core 2 / Gal(b1-4)[HSO3(-6)]GlcNAc(b1-6)[Fuc(a1-2)Gal(b1-3)]GalNAc
• O-Linked / Core 2 / HSO3(-3)Gal(b1-3)[Fuc(a1-2)]Gal(b1-3)[GlcNAc(b1-6)]GalNAc
• O-Linked / Core 2 / HSO3(-3)Gal(b1-4)GlcNAc(b1-6)[Fuc(a1-2)Gal(b1-3)]GalNAc
• O-Linked / Undefined core / Fuc(?1-2)Gal(?1-4)[HSO3(-6)]GlcNAc(?1-6)[Gal(?1-3)]GalNAc
• O-Linked / Undefined core / Gal(?1-4)[HSO3(-6)]GlcNAc(?1-6)[Fuc(?1-2)Gal(?1-3)]GalNAc
• O-Linked / Undefined core / HSO3(-3)Gal(b1-4)GlcNAc(?1-6)[Fuc(a1-2)Gal(b1-3)]GalNAc

Composition

• Hex:2 HexNAc:2 dHex:1 Su:1 (avg mass : 974.8973 )

Disease

• Bronchitis, Chronic (DOID:6132)
• Cystic Fibrosis (DOID:1485)

Reference

• Sulfated oligosaccharides isolated from the respiratory mucins of a secretor patient suffering from chronic bronchitis. (2003 - Degroote S, Maes E, Humbert P, Delmotte P, Lamblin G, Roussel P) / Status : Reviewed
• Acquisition of species-specific O-linked carbohydrate chains from oviducal mucins in Rana arvalis. A case study (1999 - Coppin, Maes, Flahaut, Coddeville, Strecker) / Status : Reviewed
• The glycosylation of rat intestinal Muc2 mucin varies between rat strains and the small and large intestine. A study of O-linked oligosaccharides by a mass spectrometric approach. (1997 - Karlsson N, Herrmann A, Karlsson H, Johansson M, Carlstedt I, Hansson G) / Status : Reviewed
• Molecular characterization of the large heavily glycosylated domain glycopeptide from the rat small intestinal Muc2 mucin. (1996 - Karlsson N, Johansson M, Asker N, Karlsson H, Gendler S, Carlstedt I, Hansson G) / Status : Reviewed
• Sialylation and sulfation of the carbohydrate chains in respiratory mucins from a patient with cystic fibrosis. (1994 - Lo-Guidice J, Wieruszeski J, Lemoine J, Verbert A, Roussel P, Lamblin G) / Status : Reviewed
• Structural features of carbohydrate chains in human salivary mucins. (1993 - Slomiany B, Murty V, Slomiany A) / Status : Reviewed
• Structure of two sulphated oligosaccharides from respiratory mucins of a patient suffering from cystic fibrosis. A fast-atom-bombardment m.s. and 1H-n.m.r. spectroscopic study. (1991 - Lamblin G, Rahmoune H, Wieruszeski J, Lhermitte M, Strecker G, Roussel P) / Status : Reviewed
• Structure of acidic oligosaccharides isolated from pronase-treated glycoprotein of bonnet-monkey (Macaca radiata) cervical mucus. (1987 - Nasir-ud-Din ) / Status : Reviewed
• Isolation and characterization of oligosaccharides from canine submaxillary mucin. (1974 - Lombart C, Winzler R) / Status : Reviewed

Reported glycosite

• Mucin-5B / Homo sapiens
  •        Undefined site
• Mucin-7 / Homo sapiens
  •        Undefined site
• Unspecified mucin / Homo sapiens
  •        Undefined site
• Mucin / Canis familiaris
  •        Undefined site
• Mucin / Macaca radiata
  •        Undefined site
• Mucin-2 glycopeptide a / Rattus norvegicus
  •        Undefined site
• Mucin / Rana arvalis
  •        Undefined site

Mass spectrometry observed peptide