Hex:4 HexNAc:6 NeuAc:1

Taxonomy

• Homo sapiens (Human)
• Gallus gallus (Chicken)
• Torpedo californica (Pacific electric ray)
• Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)

Protein

• Angiotensin-converting enzyme 2 / Homo sapiens    Q9BYF1
• Arylsulfatase D / Homo sapiens    P51689
• Clusterin / Homo sapiens    P10909
• Coagulation factor V / Homo sapiens    P12259
• Collagen alpha-1(XII) chain / Homo sapiens    Q99715
• Dipeptidyl peptidase 1 / Homo sapiens    P53634
• GDNF family receptor alpha-1 / Homo sapiens    P56159
• Golgi membrane protein 1 / Homo sapiens    Q8NBJ4
• HLA class I histocompatibility antigen, B-15 alpha chain / Homo sapiens    P30464
• HLA class I histocompatibility antigen, B-18 alpha chain / Homo sapiens    P30466
• HLA class I histocompatibility antigen, B-39 alpha chain / Homo sapiens    P30475
• HLA class I histocompatibility antigen, B-46 alpha chain / Homo sapiens    P30484
• HLA class I histocompatibility antigen, B-67 alpha chain / Homo sapiens    Q29836
• HLA class I histocompatibility antigen, B-82 alpha chain / Homo sapiens    Q29718
• HLA class I histocompatibility antigen, Cw-12 alpha chain / Homo sapiens    P30508
• HLA class I histocompatibility antigen, Cw-17 alpha chain / Homo sapiens    Q95604
• HLA class I histocompatibility antigen, Cw-2 alpha chain / Homo sapiens    P30501
• HLA class I histocompatibility antigen, Cw-5 alpha chain / Homo sapiens    Q9TNN7
• HLA class I histocompatibility antigen, Cw-8 alpha chain / Homo sapiens    P30505
• Immunoglobulin heavy constant alpha 1 / Homo sapiens    P01876
• Immunoglobulin heavy constant gamma 4 / Homo sapiens    P01861
• Immunoglobulin heavy constant mu / Homo sapiens    P01871
• Immunoglobulin J chain / Homo sapiens    P01591
• Integrin alpha-1 / Homo sapiens    P56199
• Myelin protein P0 / Homo sapiens    P25189
• Olfactomedin-like protein 3 / Homo sapiens    Q9NRN5
• Phospholipid transfer protein / Homo sapiens    P55058
• Polymeric immunoglobulin receptor / Homo sapiens    P01833
• Pregnancy zone protein / Homo sapiens    P20742
• Prolactin-inducible protein / Homo sapiens    P12273
• Prostaglandin-h2 d-isomerase / Homo sapiens    P41222
• Prostate-specific antigen (psa-1) / Homo sapiens    P07288
• Prostate-specific antigen - high Pi isoform (psah) / Homo sapiens    P07288
• Thrombospondin-1 / Homo sapiens    P07996
• Type 2 lactosamine alpha-2,3-sialyltransferase / Homo sapiens    Q9Y274
• Uromodulin / Homo sapiens    P07911
• WAP four-disulfide core domain protein 2 / Homo sapiens    Q14508
• Acetylcholine receptor protein / Torpedo californica    P02710    P02714    P02718    P02712
• Recombinant Spike glycoprotein (FreeStyle 293-F) / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)    P0DTC2
• Recombinant Spike glycoprotein (HEK293) / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)    P0DTC2

Source

• Blood Plasma (UBERON_0001969)  
• Blood Serum (UBERON_0001977)  
• Electric Organ (UBERON_0006869)  
• Mammary Gland (UBERON_0001911)  
• Milk (UBERON_0001913)  
• Prefrontal Cortex (UBERON:0000451)  
• Seminal Fluid (UBERON_0006530)  
• Umbilical Vein (UBERON_0002066)   Endothelial Cell of Umbilical Vein (CL_0002618)  
• Urine (UBERON_0001088)  
• FreeStyle 293-F (CVCL_D603)  
• HEK293 (CVCL_0045)  
• Egg Cell   Egg White  

Reported structure

• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-4)[GlcNAc(b1-2)]Man(a1-3)[GlcNAc(b1-2)Man(a1-6)][GlcNAc(b1-4)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ NeuAc"
• N-Linked / Complex / Structure 9537
• N-Linked / Complex / Structure 9759
• N-Linked / Complex / Structure 11164
• N-Linked / Complex / Structure 11177
• N-Linked / Complex / Structure 11881

Composition

• Hex:4 HexNAc:6 NeuAc:1 (avg mass : 2177.0128 )

Disease

• Cancer, breast (DOID:1612)
• Control/Healthy
• COVID-19 (DOID:0080600)
• Prostate cancer (DOID:10283)

Reference

• Site-specific N-glycosylation Characterization of Recombinant SARS-CoV-2 Spike Proteins using High-Resolution Mass Spectrometry (2020 - Yong Zhang, Wanjun Zhao, Yonghong Mao, Shisheng Wang, Yi Zhong, Tao Su, Meng Gong, Xiaofeng Lu, Jingqiu Cheng, Hao Yang) / Status : Reviewed
• Site-specific glycan analysis of the SARS-CoV-2 spike (2020 - Yasunori Watanabe, Joel D. Allen, Daniel Wrapp, Jason S. McLellan, Max Crispin) / Status : Unreviewed
• Comprehensive characterization of N- and O- glycosylation of SARS-CoV-2 human receptor angiotensin converting enzyme 2. (2020 - Asif Shajahan, Stephanie Archer-Hartmann, Nitin T. Supekar, Anne S. Gleinich, Christian Heiss, and Parastoo Azadi) / Status : Reviewed
• Comprehensive N- and O-glycosylation mapping of human coagulation factor V. (2020 - Ma C, Liu D, Li D, Zhang J, Xu XQ, Zhu H, Wan XF, Miao CH, Konkle BA, Onigman P, Xiao W, Li L) / Status : Reviewed
• Quantitative Longitudinal Inventory of the N-Glycoproteome of Human Milk from a Single Donor Reveals the Highly Variable Repertoire and Dynamic Site-Specific Changes (2020 - Jing Zhu, Yu-Hsien Lin, Kelly A Dingess, Marko Mank, Bernd Stahl, Albert J R Heck) / Status : Reviewed
• Spatial and temporal diversity of glycome expression in mammalian brain (2020 - Lee J, Ha S, Kim M, Kim SW, Yun J, Ozcan S, Hwang H, Ji IJ, Yin D, Webster MJ, Shannon Weickert C, Kim JH, Yoo JS, Grimm R, Bahn S, Shin HS, An HJ) / Status : Reviewed
• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed
• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• Efficient and accurate glycopeptide identification pipeline for high-throughput site-specific N-glycosylation analysis (2014 - Liu M, Zhang Y, Chen Y, Yan G, Shen C, Cao J, Zhou X, Liu X, Zhang L, Shen H, Lu H, He F, Yang P) / Status : Reviewed
• Glycoproteomics: Identifying the Glycosylation of Prostate Specific Antigen at Normal and High Isoelectric Points by LC-MS/MS (2014 - Song E, Mayampurath A, Yu CY, Tang H, Mechref Y) / Status : Reviewed
• Glycoproteomic analysis of the secretome of human endothelial cells (2013 - Yin X, Bern M, Xing Q, Ho J, Viner R, Mayr M.) / Status : Reviewed
• Strategic glycan elution map for the production of human-type N-linked oligosaccharides: the case of hen egg yolk and white. (2009 - Sumiyoshi W, Nakakita S, Miyanishi N, Hirabayashi J) / Status : Reviewed
• Detailed structural analysis of asparagine-linked oligosaccharides of the nicotinic acetylcholine receptor from Torpedo californica. (1992 - Shoji H, Takahashi N, Nomoto H, Ishikawa M, Shimada I, Arata Y, Hayashi K) / Status : Reviewed

Reported glycosite

• Angiotensin-converting enzyme 2 / Homo sapiens
  •        Undefined site
• Arylsulfatase D / Homo sapiens
  •        Asn-347
• Clusterin / Homo sapiens
  •        Asn-374
• Coagulation factor V / Homo sapiens
  •        Asn-2209
• Collagen alpha-1(XII) chain / Homo sapiens
  •        Asn-2679
• Dipeptidyl peptidase 1 / Homo sapiens
  •        Asn-53
  •        Asn-276
• GDNF family receptor alpha-1 / Homo sapiens
  •        Asn-59
• Golgi membrane protein 1 / Homo sapiens
  •        Asn-109
• HLA class I histocompatibility antigen, B-15 alpha chain / Homo sapiens
  •        Asn-110
• HLA class I histocompatibility antigen, B-18 alpha chain / Homo sapiens
  •        Asn-110
• HLA class I histocompatibility antigen, B-39 alpha chain / Homo sapiens
  •        Asn-110
• HLA class I histocompatibility antigen, B-46 alpha chain / Homo sapiens
  •        Asn-110
• HLA class I histocompatibility antigen, B-67 alpha chain / Homo sapiens
  •        Asn-110
• HLA class I histocompatibility antigen, B-82 alpha chain / Homo sapiens
  •        Asn-110
• HLA class I histocompatibility antigen, Cw-12 alpha chain / Homo sapiens
  •        Asn-110
• HLA class I histocompatibility antigen, Cw-17 alpha chain / Homo sapiens
  •        Asn-110
• HLA class I histocompatibility antigen, Cw-2 alpha chain / Homo sapiens
  •        Asn-110
• HLA class I histocompatibility antigen, Cw-5 alpha chain / Homo sapiens
  •        Asn-110
• HLA class I histocompatibility antigen, Cw-8 alpha chain / Homo sapiens
  •        Asn-110
• Immunoglobulin heavy constant alpha 1 / Homo sapiens
  •        Asn-340
• Immunoglobulin heavy constant gamma 4 / Homo sapiens
  •        Asn-177
• Immunoglobulin heavy constant mu / Homo sapiens
  •        Asn-209
• Immunoglobulin J chain / Homo sapiens
  •        Asn-71
• Integrin alpha-1 / Homo sapiens
  •        Asn-317
• Myelin protein P0 / Homo sapiens
  •        Asn-122
• Olfactomedin-like protein 3 / Homo sapiens
  •        Asn-248
• Phospholipid transfer protein / Homo sapiens
  •        Asn-117
• Polymeric immunoglobulin receptor / Homo sapiens
  •        Asn-83
  •        Asn-186
  •        Asn-469
• Pregnancy zone protein / Homo sapiens
  •        Asn-997
• Prolactin-inducible protein / Homo sapiens
  •        Asn-105
• Prostaglandin-h2 d-isomerase / Homo sapiens
  •        Asn-51
  •        Asn-78
• Prostate-specific antigen (psa-1) / Homo sapiens
  •        Asn-69
• Prostate-specific antigen - high Pi isoform (psah) / Homo sapiens
  •        Asn-69
• Thrombospondin-1 / Homo sapiens
  •        Asn-248
• Type 2 lactosamine alpha-2,3-sialyltransferase / Homo sapiens
  •        Asn-308
• Uromodulin / Homo sapiens
  •        Asn-513
• WAP four-disulfide core domain protein 2 / Homo sapiens
  •        Asn-44
• Acetylcholine receptor protein / Torpedo californica
  •        Undefined site
• Recombinant Spike glycoprotein (FreeStyle 293-F) / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
  •        Asn-74
  •        Asn-1098
• Recombinant Spike glycoprotein (HEK293) / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
  •        Asn-122

Mass spectrometry observed peptide

• TGVCPELQADQNCTQECVSDSECADNLK (28aa)
  •    Q14508    Asn-44     WAP four-disulfide core domain protein 2 / Homo sapiens
• WFSAGLASNSSWLREK (16aa)
  •    P41222    Asn-51     Prostaglandin-h2 d-isomerase / Homo sapiens
• DVNCSVMGPQEK (12aa)
  •    P53634    Asn-53     Dipeptidyl peptidase 1 / Homo sapiens
• ETNFSIASGIEAK (13aa)
  •    P56159    Asn-59     GDNF family receptor alpha-1 / Homo sapiens
• AVCGGVLVHPQWVLTAAHCIRNK (23aa)
  •    P07288    Asn-69     Prostate-specific antigen - high Pi isoform (psah) / Homo sapiens
• NKSVLLGR (8aa)
  •    P07288    Asn-69     Prostate-specific antigen (psa-1) / Homo sapiens
  •    P07288    Asn-69     Prostate-specific antigen - high Pi isoform (psah) / Homo sapiens
• FHAIHVSGTNGTKRF (15aa)
  •    P0DTC2    Asn-74     Recombinant Spike glycoprotein (FreeStyle 293-F) / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
• SVVAPATDGGLNLTSTFLR (19aa)
  •    P41222    Asn-78     Prostaglandin-h2 d-isomerase / Homo sapiens
• RANLTNFPENGTFVVNIAQLSQDDSGRY (28aa)
  •    P01833    Asn-83     Polymeric immunoglobulin receptor / Homo sapiens
• TFYWDFYTNR (10aa)
  •    P12273    Asn-105     Prolactin-inducible protein / Homo sapiens
• AVIVNNITTGER (12aa)
  •    Q8NBJ4    Asn-109     Golgi membrane protein 1 / Homo sapiens
• GYYNQSEAGSHTIQR (15aa)
  •    P30505    Asn-110     HLA class I histocompatibility antigen, Cw-8 alpha chain / Homo sapiens
  •    Q95604    Asn-110     HLA class I histocompatibility antigen, Cw-17 alpha chain / Homo sapiens
  •    P30464    Asn-110     HLA class I histocompatibility antigen, B-15 alpha chain / Homo sapiens
  •    P30484    Asn-110     HLA class I histocompatibility antigen, B-46 alpha chain / Homo sapiens
  •    Q9TNN7    Asn-110     HLA class I histocompatibility antigen, Cw-5 alpha chain / Homo sapiens
  •    P30508    Asn-110     HLA class I histocompatibility antigen, Cw-12 alpha chain / Homo sapiens
  •    P30466    Asn-110     HLA class I histocompatibility antigen, B-18 alpha chain / Homo sapiens
  •    Q29836    Asn-110     HLA class I histocompatibility antigen, B-67 alpha chain / Homo sapiens
  •    P30501    Asn-110     HLA class I histocompatibility antigen, Cw-2 alpha chain / Homo sapiens
  •    P30475    Asn-110     HLA class I histocompatibility antigen, B-39 alpha chain / Homo sapiens
  •    Q29718    Asn-110     HLA class I histocompatibility antigen, B-82 alpha chain / Homo sapiens
• DGSIVIHNLDYSDNGTFTCDVK (22aa)
  •    P25189    Asn-122     Myelin protein P0 / Homo sapiens
• TQSLLIVNNATNVVIK (16aa)
  •    P0DTC2    Asn-122     Recombinant Spike glycoprotein (HEK293) / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
• KQIGLYPVLVIDSSGYVNPNYTGRIRL (27aa)
  •    P01833    Asn-186     Polymeric immunoglobulin receptor / Homo sapiens
• RGLTFQQNASSMCVPDQDTAIRV (23aa)
  •    P01871    Asn-209     Immunoglobulin heavy constant mu / Homo sapiens
• GCSSSTSVLLTLDNNVVNGSSPAIR (25aa)
  •    P07996    Asn-248     Thrombospondin-1 / Homo sapiens
• FHLANR (6aa)
  •    Q9NRN5    Asn-248     Olfactomedin-like protein 3 / Homo sapiens
• IITNNSQTPIISPQEVVSCSQYAQGCEGGFPYIIAGK (37aa)
  •    P53634    Asn-276     Dipeptidyl peptidase 1 / Homo sapiens
• NVTAEQLFLK (10aa)
  •    Q9Y274    Asn-308     Type 2 lactosamine alpha-2,3-sialyltransferase / Homo sapiens
• GNISTEK (7aa)
  •    P56199    Asn-317     Integrin alpha-1 / Homo sapiens
• RLAGKPTHVNVSVVMAEVDGTCY- (24aa)
  •    P01876    Asn-340     Immunoglobulin heavy constant alpha 1 / Homo sapiens
• IEDNGLKNST (10aa)
  •    P51689    Asn-347     Arylsulfatase D / Homo sapiens
• IANITQGEDQYYIR (14aa)
  •    P10909    Asn-374     Clusterin / Homo sapiens
• VPGNVTAVIGETIK (14aa)
  •    P01833    Asn-469     Polymeric immunoglobulin receptor / Homo sapiens
• FALLMTNCYATPSSNATDPLK (21aa)
  •    P07911    Asn-513     Uromodulin / Homo sapiens
• IYVLNYLNETQQLTQEIK (18aa)
  •    P20742    Asn-997     Pregnancy zone protein / Homo sapiens
• NGTHWFV (7aa)
  •    P0DTC2    Asn-1098     Recombinant Spike glycoprotein (FreeStyle 293-F) / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
• EAGNITTDGYEIIGK (15aa)
  •    Q99715    Asn-2679     Collagen alpha-1(XII) chain / Homo sapiens