Hex:4 HexNAc:5 dHex:2 NeuAc:1

Taxonomy

• Homo sapiens (Human)
• Rattus norvegicus (Norway rat)
• Sus scrofa (Pig)
• Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)

Protein

• Alpha-1-acid glycoprotein 1 / Homo sapiens    P02763
• Alpha-1-acid glycoprotein 2 / Homo sapiens    P19652
• Alpha-1-antichymotrypsin / Homo sapiens    P01011
• Alpha-1-antitrypsin / Homo sapiens    P01009
• Alpha-2-HS-glycoprotein / Homo sapiens    P02765
• Alpha-2-macroglobulin / Homo sapiens    P01023
• Biglycan / Homo sapiens    P21810
• CD59 glycoprotein / Homo sapiens    P13987
• Ceruloplasmin / Homo sapiens    P00450
• Clusterin / Homo sapiens    P10909
• Decorin / Homo sapiens    P07585
• Deoxyribonuclease-1 / Homo sapiens    P24855
• Desmoglein-2 / Homo sapiens    Q14126
• Dipeptidyl peptidase 1 / Homo sapiens    P53634
• Disintegrin and metalloproteinase domain-containing protein 15 / Homo sapiens    Q13444
• Ephrin-A3 / Homo sapiens    P52797
• Fibromodulin / Homo sapiens    Q06828
• Glycodelin-a / Homo sapiens    P09466
• Golgi apparatus protein 1 / Homo sapiens    Q92896
• Haptoglobin / Homo sapiens    P00738
• Hemopexin / Homo sapiens    P02790
• Histidine-rich glycoprotein / Homo sapiens    P04196
• HLA class I histocompatibility antigen, A-23 alpha chain / Homo sapiens    P30447
• HLA class I histocompatibility antigen, A-24 alpha chain / Homo sapiens    P05534
• Immunoglobulin heavy constant alpha 2 / Homo sapiens    P01877
• Inter-alpha-trypsin inhibitor heavy chain h4 / Homo sapiens    Q14624
• Interstitial collagenase / Homo sapiens    P03956
• Lactotransferrin / Homo sapiens    P02788
• Lumican / Homo sapiens    P51884
• Metalloproteinase inhibitor 1 / Homo sapiens    P01033
• Nephronectin / Homo sapiens    Q6UXI9
• Olfactomedin-like protein 3 / Homo sapiens    Q9NRN5
• Polymeric immunoglobulin receptor / Homo sapiens    P01833
• Prolargin / Homo sapiens    P51888
• Prominin-1 / Homo sapiens    O43490
• Prosaposin / Homo sapiens    P07602
• Prostaglandin-h2 d-isomerase / Homo sapiens    P41222
• Prostate-specific antigen (psa-1) / Homo sapiens    P07288
• Protein CREG1 / Homo sapiens    O75629
• Serotransferrin / Homo sapiens    P02787
• Thrombospondin-1 / Homo sapiens    P07996
• Uromodulin / Homo sapiens    P07911
• Vitamin k-dependent protein c / Homo sapiens    P04070
• Zinc-alpha-2-glycoprotein / Homo sapiens    P25311
• Neuroligin 1 / Rattus norvegicus    Q62765
• Major seminal plasma glycoprotein psp-i / Sus scrofa    P35495
• Major seminal plasma glycoprotein psp-ii / Sus scrofa    P35496
• Mucin / Sus scrofa    
• Recombinant Spike glycoprotein (FreeStyle 293-F) / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)    P0DTC2

Source

• Acetabular Part of Hip Bone (UBERON_0001269)   HT-1080 (CVCL_0317)   Fibroblast (CL_0000057)  
• Amniotic Fluid (UBERON_0000173)  
• Blood Serum (UBERON_0001977)  
• Kidney (UBERON_0002113)   HEK293 (CVCL_0045)  
• Kidney (UBERON_0002113)   HEK293-EBNA (CVCL_6974)  
• Mammary Gland (UBERON_0001911)  
• Milk (UBERON_0001913)  
• Seminal Fluid (UBERON_0006530)  
• Trachea (UBERON_0003126)  
• Urine (UBERON_0001088)  
• FreeStyle 293-F (CVCL_D603)  

Reported structure

• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-2)Man(a1-?)[GalNAc(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"+ Fuc(a1-3) + NeuAc"
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-2)Man(a1-?)[GalNAc(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"+ Fuc(a1-3) + NeuAc(a2-6)"
• N-Linked / Complex / Hex(?1-?)HexNAc(?1-?)Man(a1-?)[HexNAc(?1-?)HexNAc(?1-?)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(?1-?)]GlcNAc+"+ NeuAc + Fuc"
• N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[Fuc(a1-3)[GalNAc(b1-4)]GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Structure 413
• N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[Fuc(a1-3)[GalNAc(b1-4)]GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Structure 2428
• N-Linked / Complex / Structure 9485
• O-Linked / Core 2 / Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)[GlcNAc(b1-6)]Gal(b1-4)GlcNAc(b1-3)[NeuAc(a2-6)]Gal(b1-3)[Fuc(a1-2)Gal(b1-4)GlcNAc(b1-6)]GalNAc

Composition

• Hex:4 HexNAc:5 dHex:2 NeuAc:1 (avg mass : 2266.1038 )

Disease

• Cancer, breast (DOID:1612)
• COVID-19 (DOID:0080600)
• Fibrosarcoma (DOID:3355)
• Prostate cancer (DOID:10283)

Reference

• Site-specific glycan analysis of the SARS-CoV-2 spike (2020 - Yasunori Watanabe, Joel D. Allen, Daniel Wrapp, Jason S. McLellan, Max Crispin) / Status : Unreviewed
• Quantitative Longitudinal Inventory of the N-Glycoproteome of Human Milk from a Single Donor Reveals the Highly Variable Repertoire and Dynamic Site-Specific Changes (2020 - Jing Zhu, Yu-Hsien Lin, Kelly A Dingess, Marko Mank, Bernd Stahl, Albert J R Heck) / Status : Reviewed
• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed
• Large-scale intact glycopeptide identification by Mascot database search (2018 - Ravi Chand Bollineni, Christian Jeffrey Koehler, Randi Elin Gislefoss, Jan Haug Anonsen, Bernd Thiede) / Status : Unreviewed
• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• Site-specific glycan microheterogeneity of inter-alpha-trypsin inhibitor heavy chain H4 (2014 - Chandler KB, Brnakova Z, Sanda M, Wang S, Stalnaker SH, Bridger R, Zhao P, Wells L, Edwards NJ, Goldman R.) / Status : Reviewed
• Glycoproteomics: Identifying the Glycosylation of Prostate Specific Antigen at Normal and High Isoelectric Points by LC-MS/MS (2014 - Song E, Mayampurath A, Yu CY, Tang H, Mechref Y) / Status : Reviewed
• Structural characterization of recombinant soluble rat neuroligin 1: mapping of secondary structure and glycosylation by mass spectrometry. (2004 - Hoffman RC, Jennings LL, Tsigelny I, Comoletti D, Flynn RE, Sudhof TC, Taylor P) / Status : Reviewed
• Structural characterization of the oligosaccharide chains of native and crystallized boar seminal plasma spermadhesin PSP-I and PSP-II glycoforms. (1999 - Nimtz M, Grabenhorst E, Conradt H, Sanz L, Calvete J) / Status : Reviewed
• N-glycan structures of matrix metalloproteinase-1 derived from human fibroblasts and from HT-1080 fibrosarcoma cells. (1999 - Saarinen J, Welgus H, Flizar C, Kalkkinen N, Helin J) / Status : Reviewed
• Structural analysis of the oligosaccharides derived from glycodelin, a human glycoprotein with potent immunosuppressive and contraceptive activities. (1995 - Dell A, Morris H, Easton R, Panico M, Patankar M, Oehniger S, Koistinen R, Koistinen H, Seppala M, Clark G) / Status : Reviewed
• Novel Asn-linked oligosaccharides terminating in GalNAc beta (1-->4)[Fuc alpha (1-->3)]GlcNAc beta (1-->.) are present in recombinant human protein C expressed in human kidney 293 cells. (1993 - Yan S, Chao Y, van Halbeek H) / Status : Reviewed
• Structures of the sialylated oligosaccharide chains in swine tracheal mucin glycoproteins. (1987 - Rana SS, Chandrasekaran EV, Mendicino J) / Status : Reviewed

Reported glycosite

• Alpha-1-acid glycoprotein 1 / Homo sapiens
  •        Asn-72
• Alpha-1-acid glycoprotein 2 / Homo sapiens
  •        Asn-72
• Alpha-1-antichymotrypsin / Homo sapiens
  •        Asn-127
• Alpha-1-antitrypsin / Homo sapiens
  •        Asn-271
• Alpha-2-HS-glycoprotein / Homo sapiens
  •        Asn-156
  •        Asn-176
• Alpha-2-macroglobulin / Homo sapiens
  •        Asn-1424
• Biglycan / Homo sapiens
  •        Asn-311
• CD59 glycoprotein / Homo sapiens
  •        Asn-43
• Ceruloplasmin / Homo sapiens
  •        Asn-397
• Clusterin / Homo sapiens
  •        Asn-86
  •        Asn-374
• Decorin / Homo sapiens
  •        Asn-211
• Deoxyribonuclease-1 / Homo sapiens
  •        Asn-40
• Desmoglein-2 / Homo sapiens
  •        Asn-182
• Dipeptidyl peptidase 1 / Homo sapiens
  •        Asn-276
• Disintegrin and metalloproteinase domain-containing protein 15 / Homo sapiens
  •        Asn-389
• Ephrin-A3 / Homo sapiens
  •        Asn-100
• Fibromodulin / Homo sapiens
  •        Asn-166
• Glycodelin-a / Homo sapiens
  •        Asn-81
• Golgi apparatus protein 1 / Homo sapiens
  •        Asn-210
  •        Asn-786
• Haptoglobin / Homo sapiens
  •        Asn-241
• Hemopexin / Homo sapiens
  •        Asn-64
• Histidine-rich glycoprotein / Homo sapiens
  •        Asn-125
• HLA class I histocompatibility antigen, A-23 alpha chain / Homo sapiens
  •        Asn-110
• HLA class I histocompatibility antigen, A-24 alpha chain / Homo sapiens
  •        Asn-110
• Immunoglobulin heavy constant alpha 2 / Homo sapiens
  •        Asn-205
• Inter-alpha-trypsin inhibitor heavy chain h4 / Homo sapiens
  •        Asn-207
• Interstitial collagenase / Homo sapiens
  •        Asn-120
• Lactotransferrin / Homo sapiens
  •        Asn-156
  •        Asn-497
• Lumican / Homo sapiens
  •        Asn-127
• Metalloproteinase inhibitor 1 / Homo sapiens
  •        Asn-53
• Nephronectin / Homo sapiens
  •        Asn-273
• Olfactomedin-like protein 3 / Homo sapiens
  •        Asn-248
• Polymeric immunoglobulin receptor / Homo sapiens
  •        Asn-90
  •        Asn-421
  •        Asn-469
• Prolargin / Homo sapiens
  •        Asn-327
• Prominin-1 / Homo sapiens
  •        Asn-274
• Prosaposin / Homo sapiens
  •        Asn-101
• Prostaglandin-h2 d-isomerase / Homo sapiens
  •        Asn-78
• Prostate-specific antigen (psa-1) / Homo sapiens
  •        Asn-69
• Protein CREG1 / Homo sapiens
  •        Asn-216
• Serotransferrin / Homo sapiens
  •        Asn-432
  •        Asn-630
• Thrombospondin-1 / Homo sapiens
  •        Asn-248
• Uromodulin / Homo sapiens
  •        Asn-232
• Vitamin k-dependent protein c / Homo sapiens
  •        Undefined site
• Zinc-alpha-2-glycoprotein / Homo sapiens
  •        Asn-128
• Neuroligin 1 / Rattus norvegicus
  •        Undefined site
• Major seminal plasma glycoprotein psp-i / Sus scrofa
  •        Asn-71
• Major seminal plasma glycoprotein psp-ii / Sus scrofa
  •        Asn-119
• Mucin / Sus scrofa
  •        Undefined site
• Recombinant Spike glycoprotein (FreeStyle 293-F) / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
  •        Asn-17
  •        Asn-149
  •        Asn-331

Mass spectrometry observed peptide

• QCVNLTTR (8aa)
  •    P0DTC2    Asn-17
• MSNATLVSYIVQILSR (16aa)
  •    P24855    Asn-40
• TAVNCSSDFDACIITK (16aa)
  •    P13987    Asn-43
• FVGTPEVNQTTIYQR (15aa)
  •    P01033    Asn-53
• CSDGWSFDATTLDDNGTMLFFK (22aa)
  •    P02790    Asn-64
• SVQEIQATFFYFTPNKTEDTIFLR (24aa)
  •    P02763    Asn-72
  •    P19652    Asn-72
• SVVAPATDGGLNLTSTFLR (19aa)
  •    P41222    Asn-78
• KEDALNETR (9aa)
  •    P10909    Asn-86
• RANLTNFPENGTFVVNIAQLSQDDSGRY (28aa)
  •    P01833    Asn-90
• TCNASQGFK (9aa)
  •    P52797    Asn-100
• TCDWIPKPNMSASCK (15aa)
  •    P07602    Asn-101
• YYNQSEAGSHTIQMMFGCDVGSDGR (25aa)
  •    P30447    Asn-110
  •    P05534    Asn-110
• VIDFNCTTSSVSSAIANTK (19aa)
  •    P04196    Asn-125
• LHINHNNLTESVGPLPK (17aa)
  •    P51884    Asn-127
• TLNQSSDELQLSMGNAMFVK (20aa)
  •    P01011    Asn-127
• TINQSSDEIQISMGNAMFVK (20aa)
  •    P01011    Asn-127
• FGCEIENNR (9aa)
  •    P25311    Asn-128
• YHKNNKSWMESEF (13aa)
  •    P0DTC2    Asn-149
• RTAGWNVPIGTLRPFLNWTGPPEPIEAAVARF (32aa)
  •    P02788    Asn-156
• TAGWNVPIGTIRPFINWTGPPEPIEAAVAR (30aa)
  •    P02788    Asn-156
• VCQDCPLLAPLNDTR (15aa)
  •    P02765    Asn-156
• IYIDHNNITR (10aa)
  •    Q06828    Asn-166
• AALAAFNAQNNGSNFQLEEISR (22aa)
  •    P02765    Asn-176
• INATDADEPNTINSK (15aa)
  •    Q14126    Asn-182
• TPLTANITK (9aa)
  •    P01877    Asn-205
• GNITEYQCHQYITK (14aa)
  •    Q92896    Asn-210
• IADTNITSIPQGIPPSITEIHIDGNK (26aa)
  •    P07585    Asn-211
• IVTPEEYYNVT (11aa)
  •    O75629    Asn-216
• CNTAAPMWLNGTHPSSDEGIVSR (23aa)
  •    P07911    Asn-232
• VVIHPNYSQVDIGIIK (16aa)
  •    P00738    Asn-241
• GCSSSTSVLLTLDNNVVNGSSPAIR (25aa)
  •    P07996    Asn-248
• FHLANR (6aa)
  •    Q9NRN5    Asn-248
• YIGNATAIFFIPDEGK (16aa)
  •    P01009    Asn-271
• YLGNATAIFFLPDEGK (16aa)
  •    P01009    Asn-271
• GNGTILK (7aa)
  •    Q6UXI9    Asn-273
• EALENMNSTLK (11aa)
  •    O43490    Asn-274
• IITNNSQTPIISPQEVVSCSQYAQGCEGGFPYIIAGK (37aa)
  •    P53634    Asn-276
• IIQVVYIHSNNITK (14aa)
  •    P21810    Asn-311
• INGTQICPNDIVAFHDFSSDIENVPHIR (28aa)
  •    P51888    Asn-327
• RFPNIT (6aa)
  •    P0DTC2    Asn-331
• IANITQGEDQYYIR (14aa)
  •    P10909    Asn-374
• TCIMEASTDFLPGLNFSNCSR (21aa)
  •    Q13444    Asn-389
• ENITAPGSDSAVFFEQGTTR (20aa)
  •    P00450    Asn-397
• LSLLEEPGNGTFTVILNQLTSR (22aa)
  •    P01833    Asn-421
• CGIVPVIAENYNK (13aa)
  •    P02787    Asn-432
• VPGNVTAVIGETIK (14aa)
  •    P01833    Asn-469
• TAGWNIPMGIIFNQTGSCK (19aa)
  •    P02788    Asn-497
• QQQHIFGSNVTDCSGNFCIFR (21aa)
  •    P02787    Asn-630
• NDTLQEAK (8aa)
  •    Q92896    Asn-786
• NQTLSLFFTVLQDVPVR (17aa)
  •    P01023    Asn-1424