Hex:5 HexNAc:4 dHex:1 NeuAc:1 NeuGc:1

Taxonomy

• Homo sapiens (Human)
• Bos taurus (Bovine)
• Mus musculus (House mouse)
• Sus scrofa (Pig)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009
• Alpha-2-HS-glycoprotein / Homo sapiens    P02765
• Apolipoprotein d / Homo sapiens    P05090
• CD44 antigen / Homo sapiens    P16070
• CD59 glycoprotein / Homo sapiens    P13987
• Chimeric plasminogen activator / Homo sapiens
• Leukocyte-associated immunoglobulin-like receptor 1 / Homo sapiens    Q6GTX8
• Midasin / Homo sapiens    Q9NU22
• Phosphoinositide-3-kinase-interacting protein 1 / Homo sapiens    Q96FE7
• Prostaglandin-h2 d-isomerase / Homo sapiens    P41222
• Protein-lysine 6-oxidase / Homo sapiens    P28300
• Recombinant plasminogen - [r580s] / Homo sapiens    P00750
• Roundabout homolog 4 / Homo sapiens    Q8WZ75
• Uromodulin / Homo sapiens    P07911
• Von willebrand factor / Homo sapiens    P04275
• WAP four-disulfide core domain protein 2 / Homo sapiens    Q14508
• Plasminogen / Bos taurus    P06868
• Zona pellucida sperm-binding protein matrix / Mus musculus    P20239    P10761    Q62005
• Plasminogen / Sus scrofa    P06867
• Vitronectin / Sus scrofa    P48819

Source

• Blood Plasma (UBERON_0001969)  
• Ovary (UBERON_0000992)   CHO (CVCL_0213)  
• Ovary (UBERON_0000992)  
• Umbilical Vein (UBERON_0002066)   Endothelial Cell of Umbilical Vein (CL_0002618)  
• Urine (UBERON_0001088)  
• Zona Pellucida (UBERON_0000086)  

Reported structure

• N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(?1-6)]GlcNAc
• N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc

Composition

• Hex:5 HexNAc:4 dHex:1 NeuAc:1 NeuGc:1 (avg mass : 2386.1655 )

Disease

• Prostate cancer (DOID:10283)

Reference

• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• Glycoproteomic analysis of the secretome of human endothelial cells (2013 - Yin X, Bern M, Xing Q, Ho J, Viner R, Mayr M.) / Status : Reviewed
• Structural analysis of murine zona pellucida glycans. Evidence for the expression of core 2-type O-glycans and the Sd(a) antigen. (2000 - Easton RL, Patankar MS, Lattanzio FA, Leaven TH, Morris HR, Clark GF, Dell A) / Status : Reviewed
• Primary structure of N-linked carbohydrate chains of a human chimeric plasminogen activator K2tu-PA expressed in Chinese hamster ovary cells. (1993 - Bergwerff A, van Oostrum J, Asselbergs F, Brgi R, Hokke C, Kamerling J, Vliegenthart J) / Status : Reviewed
• Structures of the N-linked oligosaccharides on porcine plasma vitronectin. (1993 - Yoneda A, Ogawa H, Matsumoto I, Ishizuka I, Hase S, Seno N) / Status : Reviewed
• Sialylated carbohydrate chains of recombinant human glycoproteins expressed in Chinese hamster ovary cells contain traces of N-glycolylneuraminic acid. (1990 - Hokke C, Bergwerff A, van Dedem G, van Oostrum J, Kamerling J, Vliegenthart J) / Status : Reviewed
• The N- and O-linked carbohydrate chains of human, bovine and porcine plasminogen. Species specificity in relation to sialylation and fucosylation patterns. (1988 - Marti T, Schaller J, Rickli E, Schmid K, Kamerling J, Gerwig G, van Halbeek H, Vliegenthart J) / Status : Reviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens
  •        Asn-271
• Alpha-2-HS-glycoprotein / Homo sapiens
  •        Asn-176
• Apolipoprotein d / Homo sapiens
  •        Asn-98
• CD44 antigen / Homo sapiens
  •        Asn-57
• CD59 glycoprotein / Homo sapiens
  •        Asn-43
• Chimeric plasminogen activator / Homo sapiens
  •        Undefined site
• Leukocyte-associated immunoglobulin-like receptor 1 / Homo sapiens
  •        Asn-69
• Midasin / Homo sapiens
  •        Asn-602
• Phosphoinositide-3-kinase-interacting protein 1 / Homo sapiens
  •        Asn-66
• Prostaglandin-h2 d-isomerase / Homo sapiens
  •        Asn-51
  •        Asn-78
• Protein-lysine 6-oxidase / Homo sapiens
  •        Asn-81
• Recombinant plasminogen - [r580s] / Homo sapiens
  •        Asn-322
• Roundabout homolog 4 / Homo sapiens
  •        Asn-246
• Uromodulin / Homo sapiens
  •        Asn-513
• Von willebrand factor / Homo sapiens
  •        Asn-156
• WAP four-disulfide core domain protein 2 / Homo sapiens
  •        Asn-44
• Plasminogen / Bos taurus
  •        Asn-315
• Zona pellucida sperm-binding protein matrix / Mus musculus
  •        Undefined site
• Plasminogen / Sus scrofa
  •        Asn-289
• Vitronectin / Sus scrofa
  •        Undefined site

Mass spectrometry observed peptide

• TGVCPELQADQNCTQECVSDSECADNLK (28aa)
  •    Q14508    Asn-44
• TAVNCSSDFDACLITK (16aa)
  •    P13987    Asn-43
• WFSAGLASNSSWLR (14aa)
  •    P41222    Asn-51
• AFNSTLPTMAQMEK (14aa)
  •    P16070    Asn-57
• CLNWLDAQSGLASAPVSGAGNHSYCR (26aa)
  •    Q96FE7    Asn-66
• SVVAPATDGGLNLTSTFLRK (20aa)
  •    P41222    Asn-78
• SVVAPATDGGLNLTSTFLR (19aa)
  •    P41222    Asn-78
• STYNDTEDVSQASPSESEAR (20aa)
  •    Q6GTX8    Asn-69
• DPGAAVPGAANASAQQPR (18aa)
  •    P28300    Asn-81
• ADGTVNQIEGEATPVNLTEPAK (22aa)
  •    P05090    Asn-98
• AALAAFNAQNNGSNFQLEEISR (22aa)
  •    P02765    Asn-176
• IQLENVTLLNPDPAEGPKPR (20aa)
  •    Q8WZ75    Asn-246
• YLGNATAIFFLPDEGK (16aa)
  •    P01009    Asn-271
• FALLMTNCYATPSSNATDPLK (21aa)
  •    P07911    Asn-513
• MAEVIGSKLNISR (13aa)
  •    Q9NU22    Asn-602