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  • Hex:5 HexNAc:4 dHex:1 NeuAc:1 NeuGc:1

Hex:5 HexNAc:4 dHex:1 NeuAc:1 NeuGc:1

SNFG, Text, Oxford
Taxonomy (4) Protein (20) Source (6) Structure (8) Composition (1) Disease (1) Site (21) Peptide (15)

    Taxonomy

  • Homo sapiens (Human)
  • Bos taurus (Bovine)
  • Sus scrofa (Pig)
  • Mus musculus (House mouse)

    Protein

  • CD59 glycoprotein / Homo sapiens    P13987
  • Leukocyte-associated immunoglobulin-like receptor 1 / Homo sapiens    Q6GTX8
  • Phosphoinositide-3-kinase-interacting protein 1 / Homo sapiens    Q96FE7
  • Roundabout homolog 4 / Homo sapiens    Q8WZ75
  • Alpha-1-antitrypsin / Homo sapiens    P01009
  • Recombinant plasminogen - [r580s] / Homo sapiens    P00750
  • Uromodulin / Homo sapiens    P07911
  • Von willebrand factor / Homo sapiens    P04275
  • Vitronectin / Sus scrofa    P48819
  • Plasminogen / Sus scrofa    P06867
  • CD44 antigen / Homo sapiens    P16070
  • Protein-lysine 6-oxidase / Homo sapiens    P28300
  • WAP four-disulfide core domain protein 2 / Homo sapiens    Q14508
  • Plasminogen / Bos taurus    P06868
  • Apolipoprotein d / Homo sapiens    P05090
  • Prostaglandin-h2 d-isomerase / Homo sapiens    P41222
  • Chimeric plasminogen activator / Homo sapiens
  • Alpha-2-hs-glycoprotein / Homo sapiens    P02765
  • Zona pellucida sperm-binding protein matrix / Mus musculus    Q62005    P10761    P20239
  • Midasin / Homo sapiens    Q9NU22

    Source

  • CHO (CVCL_0213)   Ovary (UBERON_0000992)  
  • Endothelial Cell of Umbilical Vein (CL_0002618)  
  • Blood Plasma (UBERON_0001969)  
  • Zona Pellucida (UBERON_0000086)  
  • Ovary (UBERON_0000992)  
  • Urine (UBERON_0001088)  

    Reported structure

  • N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
  • N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
  • N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
  • N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
  • N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
  • N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
  • N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(?1-6)]GlcNAc
  • N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc

    Composition

  • Hex:5 HexNAc:4 dHex:1 NeuAc:1 NeuGc:1 (avg mass : 2386.1655 )

    Disease

  • Prostate cancer (DOID:10283)

    Reported glycosite

  • Prostaglandin-h2 d-isomerase / Homo sapiens :
    •        Asn-51
    •        Asn-78
  • CD44 antigen / Homo sapiens :
    •        Asn-57
  • Uromodulin / Homo sapiens :
    •        Asn-513
  • Vitronectin / Sus scrofa :
    •        Undefined site
  • Chimeric plasminogen activator / Homo sapiens :
    •        Undefined site
  • Midasin / Homo sapiens :
    •        Asn-602
  • Plasminogen / Bos taurus :
    •        Asn-315
  • Alpha-2-hs-glycoprotein / Homo sapiens :
    •        Asn-176
  • Von willebrand factor / Homo sapiens :
    •        Undefined site
  • Plasminogen / Sus scrofa :
    •        Asn-289
  • Recombinant plasminogen - [r580s] / Homo sapiens :
    •        Asn-322
  • Phosphoinositide-3-kinase-interacting protein 1 / Homo sapiens :
    •        Asn-66
  • Apolipoprotein d / Homo sapiens :
    •        Asn-98
  • Protein-lysine 6-oxidase / Homo sapiens :
    •        Asn-81
  • Zona pellucida sperm-binding protein matrix / Mus musculus :
    •        Undefined site
  • Leukocyte-associated immunoglobulin-like receptor 1 / Homo sapiens :
    •        Asn-69
  • CD59 glycoprotein / Homo sapiens :
    •        Asn-43
  • WAP four-disulfide core domain protein 2 / Homo sapiens :
    •        Asn-44
  • Roundabout homolog 4 / Homo sapiens :
    •        Asn-246
  • Alpha-1-antitrypsin / Homo sapiens :
    •        Asn-271

    Mass spectrometry validated peptide

  • TGVCPELQADQNCTQECVSDSECADNLK (28aa)
    •    Q14508    Asn-44
  • TAVNCSSDFDACLITK (16aa)
    •    P13987    Asn-43
  • WFSAGLASNSSWLR (14aa)
    •    P41222    Asn-51
  • AFNSTLPTMAQMEK (14aa)
    •    P16070    Asn-57
  • CLNWLDAQSGLASAPVSGAGNHSYCR (26aa)
    •    Q96FE7    Asn-66
  • SVVAPATDGGLNLTSTFLRK (20aa)
    •    P41222    Asn-78
  • SVVAPATDGGLNLTSTFLR (19aa)
    •    P41222    Asn-78
  • STYNDTEDVSQASPSESEAR (20aa)
    •    Q6GTX8    Asn-69
  • DPGAAVPGAANASAQQPR (18aa)
    •    P28300    Asn-81
  • ADGTVNQIEGEATPVNLTEPAK (22aa)
    •    P05090    Asn-98
  • AALAAFNAQNNGSNFQLEEISR (22aa)
    •    P02765    Asn-176
  • IQLENVTLLNPDPAEGPKPR (20aa)
    •    Q8WZ75    Asn-246
  • YLGNATAIFFLPDEGK (16aa)
    •    P01009    Asn-271
  • FALLMTNCYATPSSNATDPLK (21aa)
    •    P07911    Asn-513
  • MAEVIGSKLNISR (13aa)
    •    Q9NU22    Asn-602
  • No image
    • N-Linked / Complex (avg mass : 2386.1655 )
    • Site (2)

        Reported glycosite

      • Plasminogen / Bos taurus :
        •        Asn-315
      • Plasminogen / Sus scrofa :
        •        Asn-289
  • No image
    • N-Linked / Complex (avg mass : 2386.1655 )
    • Site (2)

        Reported glycosite

      • Recombinant plasminogen - [r580s] / Homo sapiens :
        •        Asn-322
      • Chimeric plasminogen activator / Homo sapiens :
        •        Undefined site
  • No image
    • N-Linked / Complex (avg mass : 2386.1655 )
    • Site (1)

        Reported glycosite

      • Vitronectin / Sus scrofa :
        •        Undefined site
  • No image
    • N-Linked / Complex (avg mass : 2386.1655 )
    • Site (1)

        Reported glycosite

      • Zona pellucida sperm-binding protein matrix / Mus musculus :
        •        Undefined site
  • No image
    • N-Linked / Complex (avg mass : 2386.1655 )
    • Site (2)

        Reported glycosite

      • Plasminogen / Bos taurus :
        •        Asn-315
      • Plasminogen / Sus scrofa :
        •        Asn-289
  • No image
    • N-Linked / Complex (avg mass : 2386.1655 )
    • Site (1)

        Reported glycosite

      • Vitronectin / Sus scrofa :
        •        Undefined site
  • No image
    • N-Linked / Complex (avg mass : 2386.1655 )
    • Site (1)

        Reported glycosite

      • Vitronectin / Sus scrofa :
        •        Undefined site
  • No image
    • N-Linked / Complex (avg mass : 2386.1655 )
    • Site (2)

        Reported glycosite

      • Recombinant plasminogen - [r580s] / Homo sapiens :
        •        Asn-322
      • Chimeric plasminogen activator / Homo sapiens :
        •        Undefined site
  • 5 x 4 x 1 x 1 x 1 x
    • Hex:5 HexNAc:4 dHex:1 NeuAc:1 NeuGc:1 (avg mass : 2386.1655 )
    • Site (1) Suggested Structure (8)

        Suggested structure

      • N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
      • N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
      • N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
      • N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
      • N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
      • N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(?1-6)]GlcNAc
      • N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
      • N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc

        Reported glycosite

      • Von willebrand factor / Homo sapiens :
        •        Undefined site
  • 5 x 4 x 1 x 1 x 1 x
    • Hex:5 HexNAc:4 dHex:1 NeuAc:1 NeuGc:1 (avg mass : 2386.1655 )
    • Site (14) Suggested Structure (8)

        Suggested structure

      • N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
      • N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
      • N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
      • N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
      • N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
      • N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(?1-6)]GlcNAc
      • N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
      • N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc

        Reported glycosite

      • Prostaglandin-h2 d-isomerase / Homo sapiens :
        •        Asn-51
        •        Asn-78
      • Alpha-2-hs-glycoprotein / Homo sapiens :
        •        Asn-176
      • Phosphoinositide-3-kinase-interacting protein 1 / Homo sapiens :
        •        Asn-66
      • CD44 antigen / Homo sapiens :
        •        Asn-57
      • Uromodulin / Homo sapiens :
        •        Asn-513
      • Apolipoprotein d / Homo sapiens :
        •        Asn-98
      • Protein-lysine 6-oxidase / Homo sapiens :
        •        Asn-81
      • Leukocyte-associated immunoglobulin-like receptor 1 / Homo sapiens :
        •        Asn-69
      • CD59 glycoprotein / Homo sapiens :
        •        Asn-43
      • WAP four-disulfide core domain protein 2 / Homo sapiens :
        •        Asn-44
      • Midasin / Homo sapiens :
        •        Asn-602
      • Roundabout homolog 4 / Homo sapiens :
        •        Asn-246
      • Alpha-1-antitrypsin / Homo sapiens :
        •        Asn-271

Composition mass

Average mass : 2386.1655 Da

Monoisotopic mass : 2384.8358 Da

References (7)

Distinct urinary glycoprotein signatures in prostate cancer patients (2018)
Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano
Pubmed : 30237853   DOI : 10.18632/oncotarget.26005
Status : Unreviewed

Glycoproteomic analysis of the secretome of human endothelial cells (2013)
Yin X, Bern M, Xing Q, Ho J, Viner R, Mayr M.
Pubmed : 23345538   DOI : 10.1074/mcp.M112.024018
Status : Reviewed

Structural analysis of murine zona pellucida glycans. Evidence for the expression of core 2-type O-glycans and the Sd(a) antigen. (2000)
Easton RL, Patankar MS, Lattanzio FA, Leaven TH, Morris HR, Clark GF, Dell A
Pubmed : 10713085  
Status : Reviewed

Structures of the N-linked oligosaccharides on porcine plasma vitronectin. (1993)
Yoneda A, Ogawa H, Matsumoto I, Ishizuka I, Hase S, Seno N
Pubmed : 7506656  
Status : Reviewed

Primary structure of N-linked carbohydrate chains of a human chimeric plasminogen activator K2tu-PA expressed in Chinese hamster ovary cells. (1993)
Bergwerff A, van Oostrum J, Asselbergs F, Brgi R, Hokke C, Kamerling J, Vliegenthart J
Pubmed : 8462541  
Status : Reviewed

Sialylated carbohydrate chains of recombinant human glycoproteins expressed in Chinese hamster ovary cells contain traces of N-glycolylneuraminic acid. (1990)
Hokke C, Bergwerff A, van Dedem G, van Oostrum J, Kamerling J, Vliegenthart J
Pubmed : 2124546  
Status : Reviewed

The N- and O-linked carbohydrate chains of human, bovine and porcine plasminogen. Species specificity in relation to sialylation and fucosylation patterns. (1988)
Marti T, Schaller J, Rickli E, Schmid K, Kamerling J, Gerwig G, van Halbeek H, Vliegenthart J
Pubmed : 3356193  
Status : Reviewed

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