Hex:7 HexNAc:7 dHex:4

Taxonomy

• Homo sapiens (Human)

Protein

• Ceruloplasmin / Homo sapiens    P00450
• Fibronectin / Homo sapiens    P02751
• Lumican / Homo sapiens    P51884
• Unspecified mucin / Homo sapiens    

Source

• Mammary Gland (UBERON_0001911)  
• Pulmonary Mucosa  

Reported structure

• O-Linked / Core 2 / Fuc(a1-2)Gal(b1-4)GlcNAc(b1-6)[Fuc(a1-2)Gal(b1-?)GlcNAc(b1-3)]Gal(b1-?)GlcNAc(b1-3)[Fuc(a1-2)Gal(b1-4)GlcNAc(b1-6)]Gal(b1-?)GlcNAc(b1-3)Gal(b1-3)[Fuc(a1-2)Gal(b1-4)GlcNAc(b1-6)]GalNAc

Composition

• Hex:7 HexNAc:7 dHex:4 (avg mass : 3159.9491 )

Disease

• Cancer, breast (DOID:1612)
• Cystic Fibrosis (DOID:1485)

Reference

• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed
• Structures of sulfated oligosaccharides in human trachea mucin glycoproteins. (1993 - Sangadala S, Bhat U, Mendicino J) / Status : Reviewed

Reported glycosite

• Ceruloplasmin / Homo sapiens
  •        Asn-762
• Fibronectin / Homo sapiens
  •        Asn-528
• Lumican / Homo sapiens
  •        Asn-88
• Unspecified mucin / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

• AFENVTDLQWLILDHNLLENSK (22aa)
  •    P51884    Asn-88     Lumican / Homo sapiens
• DQCIVDDITYNVNDTFHK (18aa)
  •    P02751    Asn-528     Fibronectin / Homo sapiens
• EIHHIQEQNVSNAFIDKGEFYIGSK (25aa)
  •    P00450    Asn-762     Ceruloplasmin / Homo sapiens