Hex:7 HexNAc:7 dHex:1 NeuAc:3

Taxonomy

• Homo sapiens (Human)
• Rattus norvegicus (Norway rat)

Protein

• Carcinoembryonic antigen-related cell adhesion molecule 5 / Homo sapiens    P06731
• Erythropoietin / Homo sapiens    P01588
• Uromodulin / Homo sapiens    P07911
• Neuroligin 1 / Rattus norvegicus    Q62765

Source

• Colon (UBERON_0001155)  
• Kidney (UBERON_0002113)   HEK293-EBNA (CVCL_6974)  
• Ovary (UBERON_0000992)   CHO (CVCL_0213)  
• Urine (UBERON_0001088)  
• LS174T (CVCL_1384)  

Reported structure

• N-Linked / Complex / Structure 9327
• N-Linked / Undefined core / Hex(?1-?)HexNAc(?1-?)[NeuAc(?2-?)Hex(?1-?)HexNAc(?1-?)]Man(a1-?)[NeuAc(?2-?)Hex(?1-?)HexNAc(?1-?)[NeuAc(?2-?)Hex(?1-?)HexNAc(?1-?)]Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(?1-?)]GlcNAc+"+ HexNAc"

Composition

• Hex:7 HexNAc:7 dHex:1 NeuAc:3 (avg mass : 3595.2938 )

Disease

• Colon adenocarcinoma (DOID:234)
• Prostate cancer (DOID:10283)

Reference

• Carcinoembryonic antigen glycosylation (2021 - Kolarich D) / Status : Reviewed
• Cysteine Aminoethylation Enables the Site-Specific Glycosylation Analysis of Recombinant Human Erythropoietin using Trypsin (2020 - Steffen Lippold, Alexander Büttner, Matthew S.F. Choo, Michaela Hook, Coen J. de Jong, Terry Nguyen-Khuong, Markus Haberger, Dietmar Reusch, Manfred Wuhrer, Noortje de Haan) / Status : Reviewed
• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• Structural characterization of recombinant soluble rat neuroligin 1: mapping of secondary structure and glycosylation by mass spectrometry. (2004 - Hoffman RC, Jennings LL, Tsigelny I, Comoletti D, Flynn RE, Sudhof TC, Taylor P) / Status : Reviewed

Reported glycosite

• Carcinoembryonic antigen-related cell adhesion molecule 5 / Homo sapiens
  •        Undefined site
  •        Asn-288
• Erythropoietin / Homo sapiens
  •        Asn-65
• Uromodulin / Homo sapiens
  •        Asn-322
• Neuroligin 1 / Rattus norvegicus
  •        Undefined site

Mass spectrometry observed peptide

• SLNENITVPDTK (12aa)
  •    P01588    Asn-65     Erythropoietin / Homo sapiens
• IPNIT (5aa)
  •    P06731    Asn-288     Carcinoembryonic antigen-related cell adhesion molecule 5 / Homo sapiens
• QDFNITDISLLEHR (14aa)
  •    P07911    Asn-322     Uromodulin / Homo sapiens