GlyConnect

taxonomy (3) protein (5) source (2) structure (1) composition (1) disease (1) reference (2) site (5) peptide (3)

Taxonomy

Protein

Source

Blood Serum (UBERON_0001977)
Urine (UBERON_0001088)

Reported structure

N-Linked / Complex / Gal(b1-4)GlcNAc(?1-?)Man(a1-3)[Gal(b1-4)GlcNAc(?1-?)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ Gal(b1-4)GlcNAc(?1-?) + 2 x NeuAc(a2-?) + NeuGc(a2-?)"

Composition

Hex:6 HexNAc:5 NeuAc:2 NeuGc:1 (avg mass : 2896.6178 )

Disease

Prostate cancer (DOID:10283)

Reference

Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
Structural determination of N-linked carbohydrates by matrix-assisted laser desorption/ionization-mass spectrometry following enzymatic release within sodium dodecyl sulfate-polyacrylamide electrophoresis gels: application to species-specific glycosylation of alpha1-acid glycoprotein. (1998 - Kuster B, Hunter A, Wheeler S, Dwek R, Harvey D) / Status : Reviewed

Reported glycosite

Alpha-1-acid glycoprotein 1 / Homo sapiens
- Asn-72
Carboxypeptidase b2 / Homo sapiens
- Asn-73
CD59 glycoprotein / Homo sapiens
- Asn-43
Alpha-1-acid glycoprotein / Bos taurus
- Undefined site
Alpha-1-acid glycoprotein / Ovis aries
- Undefined site

Mass spectrometry observed peptide

- N-Linked / Complex (avg mass : 2896.6178)

- Hex:6 HexNAc:5 NeuAc:2 NeuGc:1 / N-Linked (avg mass : 2896.6178)