Hex:4 HexNAc:9 dHex:1

Taxonomy

• Homo sapiens (Human)
• Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)

Protein

• Alpha-2-macroglobulin / Homo sapiens    P01023
• Biglycan / Homo sapiens    P21810
• CD59 glycoprotein / Homo sapiens    P13987
• Glandular kallikrein 1 / Homo sapiens    P06870
• Uromodulin / Homo sapiens    P07911
• Recombinant Spike glycoprotein (HEK293) / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)    P0DTC2

Source

• Mammary Gland (UBERON_0001911)  
• Urine (UBERON_0001088)  
• HEK293 (CVCL_0045)  

Reported structure

• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-4)[GalNAc(b1-4)GlcNAc(b1-2)]Man(a1-3)[GalNAc(b1-4)GlcNAc(b1-2)[GalNAc(b1-4)GlcNAc(b1-6)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc

Composition

• Hex:4 HexNAc:9 dHex:1 (avg mass : 2641.4829 )

Disease

• Cancer, breast (DOID:1612)
• COVID-19 (DOID:0080600)
• Prostate cancer (DOID:10283)

Reference

• Site-specific N-glycosylation Characterization of Recombinant SARS-CoV-2 Spike Proteins using High-Resolution Mass Spectrometry (2020 - Yong Zhang, Wanjun Zhao, Yonghong Mao, Shisheng Wang, Yi Zhong, Tao Su, Meng Gong, Xiaofeng Lu, Jingqiu Cheng, Hao Yang) / Status : Unreviewed
• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed
• Structural elucidation of a variety of GalNAc-containing N-linked oligosaccharides from human urinary kallidinogenase. (1993 - Tomiya N, Awaya J, Kurono M, Hanzawa H, Shimada I, Arata Y, Yoshida T, Takahashi N) / Status : Reviewed

Reported glycosite

• Alpha-2-macroglobulin / Homo sapiens
  •        Asn-1424
• Biglycan / Homo sapiens
  •        Asn-311
• CD59 glycoprotein / Homo sapiens
  •        Asn-43
• Glandular kallikrein 1 / Homo sapiens
  •        Undefined site
• Uromodulin / Homo sapiens
  •        Asn-513
• Recombinant Spike glycoprotein (HEK293) / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
  •        Asn-331

Mass spectrometry observed peptide

• TAVNCSSDFDACLITK (16aa)
  •    P13987    Asn-43
• IIQVVYIHSNNITK (14aa)
  •    P21810    Asn-311
• FPNITNLCPFGE (12aa)
  •    P0DTC2    Asn-331
• FALLMTNCYATPSSNATDPLK (21aa)
  •    P07911    Asn-513
• VSNQTLSLFFTVLQDVPVR (19aa)
  •    P01023    Asn-1424