Hex:3 HexNAc:2 dHex:1 NeuAc:1

Taxonomy

• Homo sapiens (Human)
• Capra hircus (Goat)
• Bufo bufo (European toad)

Protein

• Mucin-5B / Homo sapiens    Q9HC84
• Mucin-7 / Homo sapiens    Q8TAX7
• Protein heg homolog 1 / Homo sapiens    Q9ULI3
• Mucin / Capra hircus    
• Mucin / Bufo bufo    

Source

• Saliva (UBERON_0001836)  
• Submandibular Gland (UBERON_0001736)  
• Urine (UBERON_0001088)  
• LS180 (CVCL_0397)  
• LS411N (CVCL_1385)  
• T84 (CVCL_0555)  
• Egg Cell   Jelly Coat  

Reported structure

• O-Linked / Core 1 / Fuc(a1-2)[Gal(a1-3)]Gal(b1-?)GlcNAc(b1-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc
• O-Linked / Core 1 / Gal(a1-3)GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc
• O-Linked / Core 2 / Structure 9362
• O-Linked / Undefined core / Man(a1-6)Glc(a1-4)GlcNAc(b1-4)[Fuc(a1-2)]Gal(?1-3)[NeuAc(a2-6)]GalNAc

Composition

• Hex:3 HexNAc:2 dHex:1 NeuAc:1 (avg mass : 1348.2334 )

Disease

• Cecum adenocarcinoma (DOID:3039)
• Colon adenocarcinoma (DOID:234)

Reference

• Colorectal cancer cell lines show striking diversity of their O-glycome reflecting the cellular differentiation phenotype (2021 - Katarina Madunić, Tao Zhang, Oleg A Mayboroda, Stephanie Holst, Kathrin Stavenhagen, Chunsheng Jin, Niclas G Karlsson, Guinevere S M Lageveen-Kammeijer, Manfred Wuhrer) / Status : Reviewed
• Extended Sialylated O-Glycan Repertoire of Human Urinary Glycoproteins Discovered and Characterized Using Electron-Transfer/Higher-Energy Collision Dissociation (2019 - Zsuzsanna Darula, Ádám Pap, Katalin F. Medzihradszky) / Status : Reviewed
• Structural analysis of hexa to dodecaoligosaccharide-alditols released by reductive beta-elimination from oviducal mucins of Bufo bufo. (1997 - Morelle W, Strecker G) / Status : Reviewed
• Structural features of carbohydrate chains in human salivary mucins. (1993 - Slomiany B, Murty V, Slomiany A) / Status : Reviewed
• Structures of carbohydrate chains of glycoprotein isolated from goat submaxillary mucin. (1982 - Dutta B, Rao C) / Status : Reviewed

Reported glycosite

• Mucin-5B / Homo sapiens
  •        Undefined site
• Mucin-7 / Homo sapiens
  •        Undefined site
• Protein heg homolog 1 / Homo sapiens
  •        Ser-349
• Mucin / Capra hircus
  •        Undefined site
• Mucin / Bufo bufo
  •        Undefined site

Mass spectrometry observed peptide

• SLTVSLGPVSKTEGFPK (17aa)
  •    Q9ULI3    Ser-349     Protein heg homolog 1 / Homo sapiens