Hex:3 HexNAc:4 dHex:1 NeuAc:1

Taxonomy

• Homo sapiens (Human)
• Sus scrofa (Pig)

Protein

• Asporin / Homo sapiens    Q9BXN1
• Biglycan / Homo sapiens    P21810
• Clusterin / Homo sapiens    P10909
• Decorin / Homo sapiens    P07585
• Dystroglycan / Homo sapiens    Q14118
• Erlin-1 / Homo sapiens    O75477
• Erlin-2 / Homo sapiens    O94905
• Golgin subfamily a member 4 / Homo sapiens    Q13439
• Hypoxia up-regulated protein 1 / Homo sapiens    Q9Y4L1
• Lactotransferrin / Homo sapiens    P02788
• Lysosome-associated membrane glycoprotein 1 / Homo sapiens    P11279
• Lysosome-associated membrane glycoprotein 2 / Homo sapiens    P13473
• Mammaglobin-A / Homo sapiens    Q13296
• Metalloproteinase inhibitor 1 / Homo sapiens    P01033
• Periostin / Homo sapiens    Q15063
• Prenylcysteine oxidase 1 / Homo sapiens    Q9UHG3
• Prolactin-inducible protein / Homo sapiens    P12273
• Prosaposin / Homo sapiens    P07602
• Prostate-specific antigen (psa-1) / Homo sapiens    P07288
• Protein YIPF3 / Homo sapiens    Q9GZM5
• Serpin h1 / Homo sapiens    P50454
• Thyroglobulin / Homo sapiens    P01266
• Translocon-associated protein subunit alpha / Homo sapiens    P43307
• Zinc-alpha-2-glycoprotein / Homo sapiens    P25311
• Major seminal plasma glycoprotein psp-i / Sus scrofa    P35495
• Major seminal plasma glycoprotein psp-ii / Sus scrofa    P35496

Source

• Mammary Gland (UBERON_0001911)  
• Seminal Fluid (UBERON_0006530)  
• Umbilical Vein (UBERON_0002066)   Endothelial Cell of Umbilical Vein (CL_0002618)  
• Urine (UBERON_0001088)  

Reported structure

• N-Linked / Complex / NeuAc(a2-6)GalNAc(b1-4)GlcNAc(b1-2)Man(a1-3)[Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Structure 2159
• N-Linked / Complex / Structure 9602
• O-Linked / Core 2 / Structure 9391

Composition

• Hex:3 HexNAc:4 dHex:1 NeuAc:1 (avg mass : 1754.6234 )

Disease

• Cancer, breast (DOID:1612)
• Prostate cancer (DOID:10283)
• Prostate Disease (DOID:47)

Reference

• Profiling the proteoforms of urinary prostate-specific antigen by capillary electrophoresis – mass spectrometry (2021 - Alan B. Moran, Elena Domínguez-Vega, Jan Nouta, Tamas Pongracz, Theo M. de Reijke, Manfred Wuhrer, Guinevere S.M. Lageveen-Kammeijer) / Status : Reviewed
• High-throughput glycopeptide profiling of prostate-specific antigen from seminal plasma by MALDI-MS. (2021 - Wei Wang, Anna Kałuża, Jan Nouta, Simone Nicolardi, Mirosława Ferens-Sieczkowska, Manfred Wuhrer, Guinevere S M Lageveen-Kammeijer, Noortje de Haan) / Status : Reviewed
• Novel O-linked sialoglycan structures in human urinary glycoproteins (2020 - Adam Pap, Ervin Tasnadi, Katalin F. Medzihradszky, Zsuzsanna Darula ) / Status : Reviewed
• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed
• Glycoproteomics: Identifying the Glycosylation of Prostate Specific Antigen at Normal and High Isoelectric Points by LC-MS/MS (2014 - Song E, Mayampurath A, Yu CY, Tang H, Mechref Y) / Status : Reviewed
• Glycoproteomic analysis of the secretome of human endothelial cells (2013 - Yin X, Bern M, Xing Q, Ho J, Viner R, Mayr M.) / Status : Reviewed
• Structural characterization of the oligosaccharide chains of native and crystallized boar seminal plasma spermadhesin PSP-I and PSP-II glycoforms. (1999 - Nimtz M, Grabenhorst E, Conradt H, Sanz L, Calvete J) / Status : Reviewed

Reported glycosite

• Asporin / Homo sapiens
  •        Asn-282
• Biglycan / Homo sapiens
  •        Asn-270
  •        Asn-311
• Clusterin / Homo sapiens
  •        Asn-374
• Decorin / Homo sapiens
  •        Asn-211
• Dystroglycan / Homo sapiens
  •        Asn-661
• Erlin-1 / Homo sapiens
  •        Asn-108
• Erlin-2 / Homo sapiens
  •        Asn-106
• Golgin subfamily a member 4 / Homo sapiens
  •        Asn-1612
• Hypoxia up-regulated protein 1 / Homo sapiens
  •        Asn-515
• Lactotransferrin / Homo sapiens
  •        Asn-497
• Lysosome-associated membrane glycoprotein 1 / Homo sapiens
  •        Asn-322
• Lysosome-associated membrane glycoprotein 2 / Homo sapiens
  •        Asn-58
• Mammaglobin-A / Homo sapiens
  •        Asn-53
• Metalloproteinase inhibitor 1 / Homo sapiens
  •        Asn-53
  •        Asn-101
• Periostin / Homo sapiens
  •        Asn-599
• Prenylcysteine oxidase 1 / Homo sapiens
  •        Asn-196
• Prolactin-inducible protein / Homo sapiens
  •        Asn-105
• Prosaposin / Homo sapiens
  •        Asn-215
  •        Asn-332
• Prostate-specific antigen (psa-1) / Homo sapiens
  •        Asn-69
• Protein YIPF3 / Homo sapiens
  •        Thr-346
• Serpin h1 / Homo sapiens
  •        Asn-125
• Thyroglobulin / Homo sapiens
  •        Asn-1365
• Translocon-associated protein subunit alpha / Homo sapiens
  •        Asn-136
• Zinc-alpha-2-glycoprotein / Homo sapiens
  •        Asn-109
• Major seminal plasma glycoprotein psp-i / Sus scrofa
  •        Asn-71
• Major seminal plasma glycoprotein psp-ii / Sus scrofa
  •        Asn-119

Mass spectrometry observed peptide

• FVGTPEVNQTTIYQR (15aa)
  •    P01033    Asn-53     Metalloproteinase inhibitor 1 / Homo sapiens
• ELLQEFIDDNATTNAIDELK (20aa)
  •    Q13296    Asn-53     Mammaglobin-A / Homo sapiens
• YETTNK (6aa)
  •    P13473    Asn-58     Lysosome-associated membrane glycoprotein 2 / Homo sapiens
• NK (2aa)
  •    P07288    Asn-69     Prostate-specific antigen (psa-1) / Homo sapiens
• SHNRSEEFLIAGK (13aa)
  •    P01033    Asn-101     Metalloproteinase inhibitor 1 / Homo sapiens
• TFYWDFYTNR (10aa)
  •    P12273    Asn-105     Prolactin-inducible protein / Homo sapiens
• NYTADYDK (8aa)
  •    O94905    Asn-106     Erlin-2 / Homo sapiens
  •    O75477    Asn-108     Erlin-1 / Homo sapiens
• DIVEYYNDSNGSHVIQGR (18aa)
  •    P25311    Asn-109     Zinc-alpha-2-glycoprotein / Homo sapiens
• YPQDYQFYIQNFTAIPINTVVPPQR (25aa)
  •    P43307    Asn-136     Translocon-associated protein subunit alpha / Homo sapiens
• IIHAIGGDDFIGMINR (16aa)
  •    Q9UHG3    Asn-196     Prenylcysteine oxidase 1 / Homo sapiens
• IADTNITSIPQGIPPSITEIHIDGNK (26aa)
  •    P07585    Asn-211     Decorin / Homo sapiens
• TNSTFVQALVEHVK (14aa)
  •    P07602    Asn-215     Prosaposin / Homo sapiens
• MIENGSISFIPTIR (14aa)
  •    P21810    Asn-270     Biglycan / Homo sapiens
• ITDIENGSIANIPR (14aa)
  •    Q9BXN1    Asn-282     Asporin / Homo sapiens
• IIQVVYIHSNNITK (14aa)
  •    P21810    Asn-311     Biglycan / Homo sapiens
• AANGSLR (7aa)
  •    P11279    Asn-322     Lysosome-associated membrane glycoprotein 1 / Homo sapiens
• LIDNNK (6aa)
  •    P07602    Asn-332     Prosaposin / Homo sapiens
• AVAVTLQSH (9aa)
  •    Q9GZM5    Thr-346     Protein YIPF3 / Homo sapiens
• IANITQGEDQYYIR (14aa)
  •    P10909    Asn-374     Clusterin / Homo sapiens
• TAGWNIPMGIIFNQTGSCK (19aa)
  •    P02788    Asn-497     Lactotransferrin / Homo sapiens
• VFGSQNITTVK (11aa)
  •    Q9Y4L1    Asn-515     Hypoxia up-regulated protein 1 / Homo sapiens
• EVNDTLLVNELK (12aa)
  •    Q15063    Asn-599     Periostin / Homo sapiens
• SIVVEWTNNTLPLEPCPK (18aa)
  •    Q14118    Asn-661     Dystroglycan / Homo sapiens