Hex:5 HexNAc:4 NeuGc:2

Taxonomy

• Homo sapiens (Human)
• Bos taurus (Bovine)
• Equus caballus (Domestic horse)
• Felis catus (Cat)
• Mus musculus (House mouse)
• Ovis aries (Sheep)
• Sus scrofa (Pig)

Protein

• Prostaglandin-h2 d-isomerase / Homo sapiens    P41222
• Protein AMBP / Homo sapiens    P02760
• Alpha-1-acid glycoprotein / Bos taurus    Q3SZR3
• Immunoglobulin gamma / Bos taurus    
• Plasminogen / Bos taurus    P06868
• Immunoglobulin gamma / Equus caballus    
• Immunoglobulin gamma / Felis catus    
• Alpha-1-acid glycoprotein 1 / Mus musculus    Q60590
• Alpha-1-antitrypsin 1-2 / Mus musculus    P22599
• C4b-binding protein / Mus musculus    P08607
• Carboxylesterase 1c / Mus musculus    P23953
• Ceruloplasmin / Mus musculus    Q61147
• Clusterin / Mus musculus    Q06890
• Complement c4-b / Mus musculus    P01029
• Complement factor h / Mus musculus    P06909
• Haptoglobin / Mus musculus    Q61646
• Immunoglobulin j chain / Mus musculus    P01592
• Inhibitor of carbonic anhydrase / Mus musculus    Q9DBD0
• Inter alpha-trypsin inhibitor, heavy chain 4 / Mus musculus    A6X935
• Murinoglobulin-1 / Mus musculus    P28665
• Phosphatidylinositol-glycan-specific phospholipase d / Mus musculus    O70362
• Pregnancy zone protein / Mus musculus    Q61838
• Protein ambp / Mus musculus    Q07456
• Protein tanc2 / Mus musculus    A2A690
• Serine protease inhibitor a3k / Mus musculus    P07759
• Serotransferrin / Mus musculus    Q921I1
• Zona pellucida sperm-binding protein matrix / Mus musculus    Q62005    P20239    P10761
• Alpha-1-acid glycoprotein / Ovis aries    W5P7S6
• Immunoglobulin gamma / Ovis aries    
• Plasminogen / Sus scrofa    P06867
• Vitronectin / Sus scrofa    P48819

Source

• Blood Plasma (UBERON_0001969)  
• Blood Serum (UBERON_0001977)  
• Urine (UBERON_0001088)  
• Zona Pellucida (UBERON_0000086)  

Reported structure

• N-Linked / Complex / Gal(b1-4)GlcNAc(?1-?)Man(a1-3)[Gal(b1-4)GlcNAc(?1-?)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ 2 x NeuGc(a2-?)"
• N-Linked / Complex / NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / Complex / NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / Complex / NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuGc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / Complex / Structure 3649

Composition

• Hex:5 HexNAc:4 NeuGc:2 (avg mass : 2256.0219 )

Disease

• Control/Healthy
• Prostate cancer (DOID:10283)

Reference

• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• Comparison of separation techniques for the elucidation of IgG N-glycans pooled from healthy mammalian species (2014 - Barbara Adamczyk, Tharmala Tharmalingam-Jaikaran, Michael Schomberg, Ákos Szekrényes, Ronan M.Kelly, Niclas G.Karlsson, Andràs Guttman, Pauline M.Rudd) / Status : Reviewed
• Sialic acid-focused quantitative mouse serum glycoproteomics by multiple reaction monitoring assay. (2010 - Kurogochi M, Matsushista T, Amano M, Furukawa J, Shinohara Y, Aoshima M, Nishimura S) / Status : Reviewed
• Structural analysis of trisialylated biantennary glycans isolated from mouse serum transferrin. Characterization of the sequence Neu5Gc(alpha 2-3)Gal(beta 1-3)[Neu5Gc(alpha 2-6)]GlcNAc(beta 1-2)Man. (2000 - Coddeville B, Regoeczi E, Strecker G, Plancke Y, Spik G) / Status : Reviewed
• Structural analysis of murine zona pellucida glycans. Evidence for the expression of core 2-type O-glycans and the Sd(a) antigen. (2000 - Easton RL, Patankar MS, Lattanzio FA, Leaven TH, Morris HR, Clark GF, Dell A) / Status : Reviewed
• Structural determination of N-linked carbohydrates by matrix-assisted laser desorption/ionization-mass spectrometry following enzymatic release within sodium dodecyl sulfate-polyacrylamide electrophoresis gels: application to species-specific glycosylation of alpha1-acid glycoprotein. (1998 - Kuster B, Hunter A, Wheeler S, Dwek R, Harvey D) / Status : Reviewed
• Structures of the N-linked oligosaccharides on porcine plasma vitronectin. (1993 - Yoneda A, Ogawa H, Matsumoto I, Ishizuka I, Hase S, Seno N) / Status : Reviewed
• The N- and O-linked carbohydrate chains of human, bovine and porcine plasminogen. Species specificity in relation to sialylation and fucosylation patterns. (1988 - Marti T, Schaller J, Rickli E, Schmid K, Kamerling J, Gerwig G, van Halbeek H, Vliegenthart J) / Status : Reviewed

Reported glycosite

• Prostaglandin-h2 d-isomerase / Homo sapiens
  •        Asn-51
  •        Asn-78
• Protein AMBP / Homo sapiens
  •        Asn-250
• Alpha-1-acid glycoprotein / Bos taurus
  •        Undefined site
• Immunoglobulin gamma / Bos taurus
  •        Undefined site
• Plasminogen / Bos taurus
  •        Asn-315
• Immunoglobulin gamma / Equus caballus
  •        Undefined site
• Immunoglobulin gamma / Felis catus
  •        Undefined site
• Alpha-1-acid glycoprotein 1 / Mus musculus
  •        Asn-76
• Alpha-1-antitrypsin 1-2 / Mus musculus
  •        Asn-64
• C4b-binding protein / Mus musculus
  •        Asn-74
• Carboxylesterase 1c / Mus musculus
  •        Asn-377
• Ceruloplasmin / Mus musculus
  •        Asn-138
• Clusterin / Mus musculus
  •        Asn-327
• Complement c4-b / Mus musculus
  •        Asn-1387
• Complement factor h / Mus musculus
  •        Asn-801
  •        Asn-1061
• Haptoglobin / Mus musculus
  •        Asn-148
  •        Asn-256
• Immunoglobulin j chain / Mus musculus
  •        Asn-70
• Inhibitor of carbonic anhydrase / Mus musculus
  •        Asn-664
• Inter alpha-trypsin inhibitor, heavy chain 4 / Mus musculus
  •        Asn-517
• Murinoglobulin-1 / Mus musculus
  •        Asn-313
  •        Asn-993
• Phosphatidylinositol-glycan-specific phospholipase d / Mus musculus
  •        Asn-496
• Pregnancy zone protein / Mus musculus
  •        Asn-157
  •        Asn-568
  •        Asn-1003
  •        Asn-1385
• Protein ambp / Mus musculus
  •        Asn-233
• Protein tanc2 / Mus musculus
  •        Asn-1932
• Serine protease inhibitor a3k / Mus musculus
  •        Asn-105
  •        Asn-270
• Serotransferrin / Mus musculus
  •        Undefined site
  •        Asn-513
• Zona pellucida sperm-binding protein matrix / Mus musculus
  •        Undefined site
• Alpha-1-acid glycoprotein / Ovis aries
  •        Undefined site
• Immunoglobulin gamma / Ovis aries
  •        Undefined site
• Plasminogen / Sus scrofa
  •        Asn-289
• Vitronectin / Sus scrofa
  •        Undefined site

Mass spectrometry observed peptide

• WFSAGLASNSSWLR (14aa)
  •    P41222    Asn-51     Prostaglandin-h2 d-isomerase / Homo sapiens
• SVVAPATDGGLNLTSTFLR (19aa)
  •    P41222    Asn-78     Prostaglandin-h2 d-isomerase / Homo sapiens
• YFYNGTSMACETFQYGGCMGNGNNFVTEK (29aa)
  •    P02760    Asn-250     Protein AMBP / Homo sapiens