Hex:2 HexNAc:1 NeuAc:1

Taxonomy

• Homo sapiens (Human)
• Bos taurus (Bovine)
• Oryctolagus cuniculus (Rabbit)
• Ovis aries (Sheep)
• Trypanosoma cruzi

Protein

• Erythropoietin / Homo sapiens    P01588
• Alpha-dystroglycan / Bos taurus    O18738
• Brain non dialyzable glycopeptide / Oryctolagus cuniculus    
• Dystroglycan / Ovis aries    W5PVZ9
• 35/50 kDa surface glycoprotein / Trypanosoma cruzi    
• Uncharacterized protein from Undefined tissue / Trypanosoma cruzi    

Source

• Brain (UBERON_0000955)  
• Nerve (UBERON_0001021)   Schwann Cell (CL_0002573)   Plasma Membrane (GO_0005886)  
• Ovary (UBERON_0000992)   CHO (CVCL_0213)  
• Cell Surface (GO_0009986)  

Reported structure

• O-Linked / Core 1 / Structure 9283
• O-Linked / No-core / NeuAc(?2-3)Gal(?1-4)GlcNAc(?1-2)Man
• O-Linked / No-core / NeuAc(a2-3)Gal(b1-4)[Gal(b1-6)]GlcNAc
• O-Linked / No-core / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man
• O-Linked / No-core / NeuAc(a2-3)Gal(b1-6)[Gal(b1-4)]GlcNAc
• O-Linked / No-core / NeuAc(a2-3)Gal(b1-6)[Galf(b1-4)]GlcNAc

Composition

• Hex:2 HexNAc:1 NeuAc:1 (avg mass : 836.753 )

Disease

Reference

• Cysteine Aminoethylation Enables the Site-Specific Glycosylation Analysis of Recombinant Human Erythropoietin using Trypsin (2020 - Steffen Lippold, Alexander Büttner, Matthew S.F. Choo, Michaela Hook, Coen J. de Jong, Terry Nguyen-Khuong, Markus Haberger, Dietmar Reusch, Manfred Wuhrer, Noortje de Haan) / Status : Reviewed
• A novel sialylated and galactofuranose-containing O-linked glycan, Neu5Ac alpha2-5 Galp beta1-6 (Galf beta1-4) GlcNAc, is expressed on the sialoglycoprotein of Trypanosoma cruzi Dm28c (2003 - Agrellos OA, Jones C, Todeschini AR, Previato JO, Mendonca-Previato L) / Status : Reviewed
• Structure of O-glycosidically linked oligosaccharides from glycoproteins of Trypanosoma cruzi CL-Brener strain: evidence for the presence of O-linked sialyl-oligosaccharides. (2001 - Todeschini A, da Silveira E, Jones C, Wait R, Previato J, Mendona-Previato L) / Status : Reviewed
• High prevalence of 2-mono- and 2,6-di-substituted manol-terminating sequences among O-glycans released from brain glycopeptides by reductive alkaline hydrolysis. (1999 - Chai W, Yuen C, Kogelberg H, Carruthers R, Margolis R, Feizi T, Lawson A) / Status : Reviewed
• Structural analysis of sequences O-linked to mannose reveals a novel Lewis X structure in cranin (dystroglycan) purified from sheep brain. (1998 - Smalheiser N, Haslam S, Sutton-Smith M, Morris H, Dell A) / Status : Reviewed
• Structures of sialylated O-linked oligosaccharides of bovine peripheral nerve alpha-dystroglycan. The role of a novel O-mannosyl-type oligosaccharide in the binding of alpha-dystroglycan with laminin. (1997 - Chiba A, Matsumura K, Yamada H, Inazu T, Shimizu T, Kusunoki S, Kanazawa I, Kobata A, Endo T) / Status : Reviewed

Reported glycosite

• Erythropoietin / Homo sapiens
  •        Ser-153
• Alpha-dystroglycan / Bos taurus
  •        Undefined site
• Brain non dialyzable glycopeptide / Oryctolagus cuniculus
  •        Undefined site
• Dystroglycan / Ovis aries
  •        Undefined site
• 35/50 kDa surface glycoprotein / Trypanosoma cruzi
  •        Undefined site
• Uncharacterized protein from Undefined tissue / Trypanosoma cruzi
  •        Undefined site

Mass spectrometry observed peptide

• EAISPPDAASAAPLR (15aa)
  •    P01588    Ser-153