Hex:2 HexNAc:1 NeuAc:1

Taxonomy

• Homo sapiens (Human)
• Bos taurus (Bovine)
• Oryctolagus cuniculus (Rabbit)
• Ovis aries (Sheep)
• Trypanosoma cruzi

Protein

• Angiotensin-converting enzyme 2 / Homo sapiens    Q9BYF1
• Erythropoietin / Homo sapiens    P01588
• Alpha-dystroglycan / Bos taurus    O18738
• Brain non dialyzable glycopeptide / Oryctolagus cuniculus    
• Dystroglycan / Ovis aries    W5PVZ9
• 35/50 kDa surface glycoprotein / Trypanosoma cruzi    
• Uncharacterized protein / Trypanosoma cruzi    

Source

• Brain (UBERON_0000955)  
• Nerve (UBERON_0001021)   Schwann Cell (CL_0002573)   Plasma Membrane (GO_0005886)  
• Ovary (UBERON_0000992)   CHO (CVCL_0213)  
• HEK293 (CVCL_0045)  
• Cell Surface (GO_0009986)  

Reported structure

• O-Linked / Core 1 / Structure 9283
• O-Linked / No-core / NeuAc(?2-3)Gal(?1-4)GlcNAc(?1-2)Man
• O-Linked / No-core / NeuAc(a2-3)Gal(b1-4)[Gal(b1-6)]GlcNAc
• O-Linked / No-core / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man
• O-Linked / No-core / NeuAc(a2-3)Gal(b1-6)[Gal(b1-4)]GlcNAc
• O-Linked / No-core / NeuAc(a2-3)Gal(b1-6)[Galf(b1-4)]GlcNAc

Composition

• Hex:2 HexNAc:1 NeuAc:1 (avg mass : 836.753 )

Disease

• COVID-19 (DOID:0080600)

Reference

• Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor (2020 - Peng Zhao, Jeremy L. Praissman, Oliver C. Grant, Yongfei Cai, Tianshu Xiao, Katelyn E. Rosenbalm, Kazuhiro Aoki, Benjamin P. Kellman, Robert Bridger, Dan H. Barouch, Melinda A. Brindley, Nathan E. Lewis, Michael Tiemeyer, Bing Chen, Robert J. Woods, Lance Wells) / Status : Reviewed
• Cysteine Aminoethylation Enables the Site-Specific Glycosylation Analysis of Recombinant Human Erythropoietin using Trypsin (2020 - Steffen Lippold, Alexander Büttner, Matthew S.F. Choo, Michaela Hook, Coen J. de Jong, Terry Nguyen-Khuong, Markus Haberger, Dietmar Reusch, Manfred Wuhrer, Noortje de Haan) / Status : Reviewed
• A novel sialylated and galactofuranose-containing O-linked glycan, Neu5Ac alpha2-5 Galp beta1-6 (Galf beta1-4) GlcNAc, is expressed on the sialoglycoprotein of Trypanosoma cruzi Dm28c (2003 - Agrellos OA, Jones C, Todeschini AR, Previato JO, Mendonca-Previato L) / Status : Reviewed
• Structure of O-glycosidically linked oligosaccharides from glycoproteins of Trypanosoma cruzi CL-Brener strain: evidence for the presence of O-linked sialyl-oligosaccharides. (2001 - Todeschini A, da Silveira E, Jones C, Wait R, Previato J, Mendona-Previato L) / Status : Reviewed
• High prevalence of 2-mono- and 2,6-di-substituted manol-terminating sequences among O-glycans released from brain glycopeptides by reductive alkaline hydrolysis. (1999 - Chai W, Yuen C, Kogelberg H, Carruthers R, Margolis R, Feizi T, Lawson A) / Status : Reviewed
• Structural analysis of sequences O-linked to mannose reveals a novel Lewis X structure in cranin (dystroglycan) purified from sheep brain. (1998 - Smalheiser N, Haslam S, Sutton-Smith M, Morris H, Dell A) / Status : Reviewed
• Structures of sialylated O-linked oligosaccharides of bovine peripheral nerve alpha-dystroglycan. The role of a novel O-mannosyl-type oligosaccharide in the binding of alpha-dystroglycan with laminin. (1997 - Chiba A, Matsumura K, Yamada H, Inazu T, Shimizu T, Kusunoki S, Kanazawa I, Kobata A, Endo T) / Status : Reviewed

Reported glycosite

• Angiotensin-converting enzyme 2 / Homo sapiens
  •        Undefined site
• Erythropoietin / Homo sapiens
  •        Ser-153
• Alpha-dystroglycan / Bos taurus
  •        Undefined site
• Brain non dialyzable glycopeptide / Oryctolagus cuniculus
  •        Undefined site
• Dystroglycan / Ovis aries
  •        Undefined site
• 35/50 kDa surface glycoprotein / Trypanosoma cruzi
  •        Undefined site
• Uncharacterized protein / Trypanosoma cruzi
  •        Undefined site

Mass spectrometry observed peptide

• EAISPPDAASAAPLR (15aa)
  •    P01588    Ser-153     Erythropoietin / Homo sapiens