Hex:5 HexNAc:3 dHex:2 NeuAc:1

Taxonomy

• Homo sapiens (Human)

Protein

• CD16A-NK13-V/F genotype / Homo sapiens    P08637
• Complement factor i / Homo sapiens    P05156
• Semaphorin-4D / Homo sapiens    Q92854

Source

• Blood Serum (UBERON_0001977)   Mature NK T cell (CL_0000814)  
• Blood Serum (UBERON_0001977)  
• Milk (UBERON_0001913)  

Reported structure

• Free / Lactose / [[Fuc(a1-2)]Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-6)][Neu5Ac(a2-6)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)Glc(b1-
• Free / Lactose / [Neu5Ac(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-6)][[Fuc(a1-2)]Gal(b1-3)GlcNAc(b1-3)]Gal(b1-4)Glc(b1-
• Free / Lactose / [Neu5Ac(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-6)][Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)]Gal(b1-4)Glc(b1-
• Free / Lactose / [Neu5Ac(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-6)][[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)]Gal(b1-4)Glc(b1-
• Free / Lactose / Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)]Gal(b1-4)Glc
• Free / Lactose / Fuc(a1-4)[Gal(b1-3)]GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)]Gal(b1-4)Glc
• Free / Lactose / Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)]Gal(b1-4)Glc
• Free / Lactose / Structure 10874
• Free / Lactose / Structure 10875
• Free / Lactose / Structure 10876

Composition

• Hex:5 HexNAc:3 dHex:2 NeuAc:1 (avg mass : 2021.8562 )

Disease

• Prostate cancer (DOID:10283)

Reference

• Primary Human Natural Killer Cells Retain Proinflammatory IgG1 at the Cell Surface and Express CD16a Glycoforms with Donor-dependent Variability. (2019 - Patel KR, Nott JD, Barb AW) / Status : Unreviewed
• Human milk oligosaccharides as essential tools for basic and application studies on galectins (2018 - Tadasu Urashima, Jun Hirabayashi, Sachiko Sato, Akira Kobata) / Status : Reviewed
• Large-scale intact glycopeptide identification by Mascot database search (2018 - Ravi Chand Bollineni, Christian Jeffrey Koehler, Randi Elin Gislefoss, Jan Haug Anonsen, Bernd Thiede) / Status : Unreviewed
• Synthesis of Asymmetrical Multiantennary Human Milk Oligosaccharides (2017 - Anthony R Prudden, Lin Liu, Chantelle J Capicciotti, Margreet A Wolfert, Shuo Wang, Zhongwei Gao, Lu Meng, Kelley W Moremen, Geert-Jan Boons) / Status : Reviewed
• Annotation and Structural Analysis of Sialylated Human Milk Oligosaccharides (2011 - Shuai Wu, Rudolf Grimm, J Bruce German, Carlito B Lebrilla) / Status : Reviewed
• Novel oligosaccharides with the sialyl-Lea structure in human milk. (1991 - Kitagawa H, Nakada H, Fukui S, Funakoshi I, Kawasaki T, Yamashina I, Tate S, Inagaki F) / Status : Reviewed

Reported glycosite

• CD16A-NK13-V/F genotype / Homo sapiens
  •        Asn-180
• Complement factor i / Homo sapiens
  •        Asn-494
• Semaphorin-4D / Homo sapiens
  •        Asn-379

Mass spectrometry observed peptide

• CRGLVGSKNVSSE (13aa)
  •    P08637    Asn-180     CD16A-NK13-V/F genotype / Homo sapiens
  •    VAR_003960   176:F→V   dbSNP:rs396991
• AANYTSSLNLPDK (13aa)
  •    Q92854    Asn-379     Semaphorin-4D / Homo sapiens
• LISNCSK (7aa)
  •    P05156    Asn-494     Complement factor i / Homo sapiens