Hex:4 HexNAc:6 dHex:2

Taxonomy

• Homo sapiens (Human)
• Mus musculus (House mouse)

Protein

• Afamin / Homo sapiens    P43652
• Alpha-1-acid glycoprotein 1 / Homo sapiens    P02763
• Alpha-1-acid glycoprotein 2 / Homo sapiens    P19652
• Alpha-1-antichymotrypsin / Homo sapiens    P01011
• Alpha-1-antitrypsin / Homo sapiens    P01009
• Alpha-2-hs-glycoprotein / Homo sapiens    P02765
• Antithrombin-III / Homo sapiens    P01008
• Apolipoprotein b-100 / Homo sapiens    P04114
• Apolipoprotein d / Homo sapiens    P05090
• Apolipoprotein f / Homo sapiens    Q13790
• Beta-2-glycoprotein 1 / Homo sapiens    P02749
• Beta-galactosidase / Homo sapiens    P16278
• Biglycan / Homo sapiens    P21810
• Calumenin / Homo sapiens    O43852
• Calumenin, isoform CRA_a / Homo sapiens
• Cathepsin D / Homo sapiens    P07339
• CD63 antigen / Homo sapiens    P08962
• Ceruloplasmin / Homo sapiens    P00450
• Chymotrypsin-like elastase family member 3B / Homo sapiens    P08861
• Clusterin / Homo sapiens    P10909
• CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 / Homo sapiens    Q11201
• Coiled-coil domain-containing protein 138 / Homo sapiens    Q96M89
• Collagen alpha-1(V) chain / Homo sapiens    P20908
• Collagen alpha-1(VI) chain / Homo sapiens    P12109
• Complement c4-a / Homo sapiens    P0C0L4
• Complement C4-B / Homo sapiens    P0C0L5
• Complement component c6 / Homo sapiens    P13671
• Complement component C9 / Homo sapiens    P02748
• Complement factor h / Homo sapiens    P08603
• Complement factor i / Homo sapiens    P05156
• Decorin / Homo sapiens    P07585
• Dipeptidyl peptidase 1 / Homo sapiens    P53634
• Epidermal growth factor receptor / Homo sapiens    P00533
• Fibrillin-1 / Homo sapiens    P35555
• Fibrinogen beta chain / Homo sapiens    P02675
• Fibrinogen gamma chain / Homo sapiens    P02679
• Fibronectin / Homo sapiens    P02751
• GDNF family receptor alpha-1 / Homo sapiens    P56159
• Golgi membrane protein 1 / Homo sapiens    Q8NBJ4
• Golgin subfamily A member 8A / Homo sapiens    A7E2F4
• Golgin subfamily A member 8B / Homo sapiens    A8MQT2
• Haptoglobin / Homo sapiens    P00738
• Hemopexin / Homo sapiens    P02790
• Histidine-rich glycoprotein / Homo sapiens    P04196
• Immunoglobulin heavy constant alpha 1 / Homo sapiens    P01876
• Integrin alpha-2 / Homo sapiens    P17301
• Inter-alpha-trypsin inhibitor heavy chain h2 / Homo sapiens    P19823
• Inter-alpha-trypsin inhibitor heavy chain H3 / Homo sapiens    Q06033
• Inter-alpha-trypsin inhibitor heavy chain h4 / Homo sapiens    Q14624
• Kallistatin / Homo sapiens    P29622
• Kininogen-1 / Homo sapiens    P01042
• Lumican / Homo sapiens    P51884
• Metalloproteinase inhibitor 1 / Homo sapiens    P01033
• N-acetylmuramoyl-l-alanine amidase / Homo sapiens    Q96PD5
• Nephronectin / Homo sapiens    Q6UXI9
• Olfactomedin-like protein 3 / Homo sapiens    Q9NRN5
• Plasma kallikrein / Homo sapiens    P03952
• Plasma protease c1 inhibitor / Homo sapiens    P05155
• Plasma serine protease inhibitor / Homo sapiens    P05154
• Polymeric immunoglobulin receptor / Homo sapiens    P01833
• Prolactin-inducible protein / Homo sapiens    P12273
• Prosaposin / Homo sapiens    P07602
• Selenoprotein P / Homo sapiens    P49908
• Serotransferrin / Homo sapiens    P02787
• Serum albumin / Homo sapiens    P02768
• Serum paraoxonase/arylesterase 1 / Homo sapiens    P27169
• Sodium channel protein type 4 subunit alpha / Homo sapiens    P35499
• Telomere-associated protein RIF1 / Homo sapiens    Q5UIP0
• Thyroxine-binding globulin / Homo sapiens    P05543
• Transferrin receptor protein 1 / Homo sapiens    P02786
• Vitronectin / Homo sapiens    P04004
• WAP four-disulfide core domain protein 2 / Homo sapiens    Q14508
• Zinc-alpha-2-glycoprotein / Homo sapiens    P25311
• Sodium/potassium-transporting ATPase subunit beta-1 / Mus musculus    P14094

Source

• Brain (UBERON_0000955)  
• Mammalian Vulva (UBERON_0000997)   A-431 (CVCL_0037)  
• Mammary Gland (UBERON_0001911)  
• Pancreas (UBERON_0001264)  
• Urine (UBERON_0001088)  

Reported structure

• N-Linked / Complex / Fuc(a1-2)[GalNAc(a1-3)]Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[GlcNAc(b1-2)Man(a1-6)][GlcNAc(b1-4)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / GlcNAc(b1-2)[GlcNAc(b1-6)]Man(a1-6)[GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"+ Fuc(a1-2)[GalNAc(a1-3)]Gal(b1-4)"

Composition

• Hex:4 HexNAc:6 dHex:2 (avg mass : 2178.0409 )

Disease

• Cancer, breast (DOID:1612)
• Carcinoma, Squamous cell (DOID:1749)
• Prostate cancer (DOID:10283)

Reference

• Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis (2019 - Nicholas M. Riley, Alexander S. Hebert, Michael S. Westphall & Joshua J. Coon ) / Status : Unreviewed
• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed
• Characterization of the carbohydrate chains of the secreted form of the human epidermal growth factor receptor. (2000 - Stroop C, Weber W, Gerwig G, Nimtz M, Kamerling J, Vliegenthart J) / Status : Reviewed
• Carbohydrate structure of human pancreatic elastase 1. (1991 - Wendorf P, Linder D, Sziegoleit A, Geyer R) / Status : Reviewed

Reported glycosite

• Afamin / Homo sapiens
  •        Asn-33
  •        Asn-402
• Alpha-1-acid glycoprotein 1 / Homo sapiens
  •        Asn-33
  •        Asn-56
  •        Asn-72
• Alpha-1-acid glycoprotein 2 / Homo sapiens
  •        Asn-56
  •        Asn-72
• Alpha-1-antichymotrypsin / Homo sapiens
  •        Asn-127
• Alpha-1-antitrypsin / Homo sapiens
  •        Asn-271
  •        Thr-273
• Alpha-2-hs-glycoprotein / Homo sapiens
  •        Asn-176
• Antithrombin-III / Homo sapiens
  •        Asn-128
  •        Asn-187
• Apolipoprotein b-100 / Homo sapiens
  •        Asn-2982
  •        Asn-3411
  •        Asn-3895
• Apolipoprotein d / Homo sapiens
  •        Asn-65
  •        Asn-98
• Apolipoprotein f / Homo sapiens
  •        Asn-139
• Beta-2-glycoprotein 1 / Homo sapiens
  •        Asn-253
• Beta-galactosidase / Homo sapiens
  •        Asn-464
• Biglycan / Homo sapiens
  •        Asn-270
  •        Asn-311
• Calumenin / Homo sapiens
  •        Asn-131
• Calumenin, isoform CRA_a / Homo sapiens
  •        Asn-131
• Cathepsin D / Homo sapiens
  •        Asn-263
• CD63 antigen / Homo sapiens
  •        Asn-150
• Ceruloplasmin / Homo sapiens
  •        Asn-138
  •        Asn-358
  •        Asn-397
  •        Asn-762
• Chymotrypsin-like elastase family member 3B / Homo sapiens
  •        Asn-114
• Clusterin / Homo sapiens
  •        Asn-103
  •        Asn-374
• CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 / Homo sapiens
  •        Asn-114
• Coiled-coil domain-containing protein 138 / Homo sapiens
  •        Asn-279
• Collagen alpha-1(V) chain / Homo sapiens
  •        Asn-176
• Collagen alpha-1(VI) chain / Homo sapiens
  •        Asn-804
• Complement c4-a / Homo sapiens
  •        Asn-1391
• Complement C4-B / Homo sapiens
  •        Asn-1391
• Complement component c6 / Homo sapiens
  •        Asn-324
• Complement component C9 / Homo sapiens
  •        Asn-277
• Complement factor h / Homo sapiens
  •        Asn-911
• Complement factor i / Homo sapiens
  •        Asn-103
• Decorin / Homo sapiens
  •        Asn-211
• Dipeptidyl peptidase 1 / Homo sapiens
  •        Asn-53
• Epidermal growth factor receptor / Homo sapiens
  •        Undefined site
• Fibrillin-1 / Homo sapiens
  •        Asn-1703
• Fibrinogen beta chain / Homo sapiens
  •        Asn-394
• Fibrinogen gamma chain / Homo sapiens
  •        Asn-78
• Fibronectin / Homo sapiens
  •        Asn-430
  •        Asn-528
• GDNF family receptor alpha-1 / Homo sapiens
  •        Asn-59
• Golgi membrane protein 1 / Homo sapiens
  •        Asn-109
• Golgin subfamily A member 8A / Homo sapiens
  •        Asn-117
• Golgin subfamily A member 8B / Homo sapiens
  •        Asn-89
• Haptoglobin / Homo sapiens
  •        Asn-184
  •        Asn-207
  •        Asn-211
  •        Asn-241
• Hemopexin / Homo sapiens
  •        Asn-64
• Histidine-rich glycoprotein / Homo sapiens
  •        Asn-125
• Immunoglobulin heavy constant alpha 1 / Homo sapiens
  •        Asn-340
• Integrin alpha-2 / Homo sapiens
  •        Asn-343
• Inter-alpha-trypsin inhibitor heavy chain h2 / Homo sapiens
  •        Asn-118
• Inter-alpha-trypsin inhibitor heavy chain H3 / Homo sapiens
  •        Asn-91
• Inter-alpha-trypsin inhibitor heavy chain h4 / Homo sapiens
  •        Asn-81
  •        Asn-517
• Kallistatin / Homo sapiens
  •        Asn-157
• Kininogen-1 / Homo sapiens
  •        Asn-169
  •        Asn-205
  •        Asn-294
• Lumican / Homo sapiens
  •        Asn-127
• Metalloproteinase inhibitor 1 / Homo sapiens
  •        Asn-53
• N-acetylmuramoyl-l-alanine amidase / Homo sapiens
  •        Asn-485
• Nephronectin / Homo sapiens
  •        Asn-273
• Olfactomedin-like protein 3 / Homo sapiens
  •        Asn-248
• Plasma kallikrein / Homo sapiens
  •        Asn-127
  •        Asn-396
  •        Asn-453
  •        Asn-494
• Plasma protease c1 inhibitor / Homo sapiens
  •        Asn-25
  •        Asn-253
  •        Asn-352
• Plasma serine protease inhibitor / Homo sapiens
  •        Asn-262
• Polymeric immunoglobulin receptor / Homo sapiens
  •        Asn-186
  •        Asn-469
• Prolactin-inducible protein / Homo sapiens
  •        Asn-105
• Prosaposin / Homo sapiens
  •        Asn-101
  •        Asn-332
• Selenoprotein P / Homo sapiens
  •        Asn-83
• Serotransferrin / Homo sapiens
  •        Asn-432
• Serum albumin / Homo sapiens
  •        Ser-328
• Serum paraoxonase/arylesterase 1 / Homo sapiens
  •        Asn-253
• Sodium channel protein type 4 subunit alpha / Homo sapiens
  •        Asn-1205
• Telomere-associated protein RIF1 / Homo sapiens
  •        Asn-105
• Thyroxine-binding globulin / Homo sapiens
  •        Asn-36
  •        Asn-165
• Transferrin receptor protein 1 / Homo sapiens
  •        Asn-251
• Vitronectin / Homo sapiens
  •        Asn-86
• WAP four-disulfide core domain protein 2 / Homo sapiens
  •        Thr-33
• Zinc-alpha-2-glycoprotein / Homo sapiens
  •        Asn-109
• Sodium/potassium-transporting ATPase subunit beta-1 / Mus musculus
  •        Asn-158

Mass spectrometry observed peptide

• NPNATSSSSQDPESLQDRGEGK (22aa)
  •    P05155    Asn-25
• DIENFNSTQK (10aa)
  •    P43652    Asn-33
• TGVCPELQADQNCTQECVSDSECADNLK (28aa)
  •    Q14508    Thr-33
• LVPVPITNATLDQITGK (17aa)
  •    P02763    Asn-33
• VTACHSSQPNATLYK (15aa)
  •    P05543    Asn-36
• DVNCSVMGPQEK (12aa)
  •    P53634    Asn-53
• FVGTPEVNQTTIYQR (15aa)
  •    P01033    Asn-53
• WFYIASAFRNEEYNK (15aa)
  •    P19652    Asn-56
• WFYIASAFRNEEYNK (15aa)
  •    P02763    Asn-56
• ETNFSIASGIEAK (13aa)
  •    P56159    Asn-59
• CSDGWSFDATTLDDNGTMLFFK (22aa)
  •    P02790    Asn-64
• CIQANYSIMENGK (13aa)
  •    P05090    Asn-65
• SVQEIQATFFYFTPNK (16aa)
  •    P19652    Asn-72
• SVQEIQATFFYFTPNK (16aa)
  •    P02763    Asn-72
• DLQSLEDILHQVENK (15aa)
  •    P02679    Asn-78
• AFITNFSMIIDGMTYPGIIK (20aa)
  •    Q14624    Asn-81
• AFITNFSMNIDGMTYPGIIK (20aa)
  •    Q14624    Asn-81
  •    VAR_027869   85:I→N   dbSNP:rs13072536
• EGYSNISYIVVNHQGISSR (19aa)
  •    P49908    Asn-83
• NNATVHEQVGGPSITSDIQAQSK (23aa)
  •    P04004    Asn-86
• ADGTVNQIEGEATPVNLTEPAK (22aa)
  •    P05090    Asn-98
• LNDTLK (6aa)
  •    A8MQT2    Asn-89
• LNDTLK (6aa)
  •    A7E2F4    Asn-117
• LNDTLK (6aa)
  •    Q96M89    Asn-279
• LNDTLK (6aa)
  •    Q5UIP0    Asn-105
• LNDTLK (6aa)
  •    Q11201    Asn-114
• TAFITNFTLTIDGVTYPGNVK (21aa)
  •    Q06033    Asn-91
• ADGTVNQIEGEATPVNITEPAKIEVK (26aa)
  •    P05090    Asn-98
• NMSASCK (7aa)
  •    P07602    Asn-101
• ELPGVCNETMMALWEECKPCLK (22aa)
  •    P10909    Asn-103
• FINNGTCTAEGK (12aa)
  •    P05156    Asn-103
• TFYWDFYTNR (10aa)
  •    P12273    Asn-105
• DIVEYYNDSNGSHVIQGR (18aa)
  •    P25311    Asn-109
• AVIVNNITTGER (12aa)
  •    Q8NBJ4    Asn-109
• GAFISNFSMTVDGK (14aa)
  •    P19823    Asn-118
• LHINHNNLTESVGPLPK (17aa)
  •    P51884    Asn-127
• GVNFNVSK (8aa)
  •    P03952    Asn-127
• VIDFNCTTSSVSSAIANTK (19aa)
  •    P04196    Asn-125
• TINQSSDEIQISMGNAMFVK (20aa)
  •    P01011    Asn-127
• LGACNDTLQQLMEVFKFDTISEK (23aa)
  •    P01008    Asn-128
• IGACNDTIQQIMEVFK (16aa)
  •    P01008    Asn-128
• NVTYGTYIDDPDPDDGFNYK (20aa)
  •    O43852    Asn-131
• NVTYGTYIDDPDPDDGFNYK (20aa)
• EHEGAIYPDNTTDFQR (16aa)
  •    P00450    Asn-138
• NVSVEALASALQLLAR (16aa)
  •    Q13790    Asn-139
• GAANYTDWEK (10aa)
  •    P08962    Asn-150
• FINDTMAVYEAK (12aa)
  •    P29622    Asn-157
• FKLDWLGNCSGLNDDSYGYR (20aa)
  •    P14094    Asn-158
• TLYETEVFSTDFSNISAAK (19aa)
  •    P05543    Asn-165
• HGIQYFNNNTQHSSLFTLNEVK (22aa)
  •    P01042    Asn-169
  •    VAR_019278   178:M→T   dbSNP:rs1656922
• AALAAFNAQNNGSNFQLEEISR (22aa)
  •    P02765    Asn-176
• NVTLILDCK (9aa)
  •    P20908    Asn-176
• MVSHHNITTGATIINEQWIITTAK (24aa)
  •    P00738    Asn-184
• QIGLYPVLVIDSSGYVNPNYTGR (23aa)
  •    P01833    Asn-186
• SLTFNETYQDISELVYGAK (19aa)
  •    P01008    Asn-187
• ITYSIVQTNCSK (12aa)
  •    P01042    Asn-205
• NIFINHSENATAK (13aa)
  •    P00738    Asn-207
• NIFINHSENATAK (13aa)
  •    P00738    Asn-211
• IADTNITSIPQGIPPSITEIHIDGNK (26aa)
  •    P07585    Asn-211
• VVIHPNYSQVDIGIIK (16aa)
  •    P00738    Asn-241
• FHLANR (6aa)
  •    Q9NRN5    Asn-248
• DFEDLYTPVNGSIVIVR (17aa)
  •    P02786    Asn-251
• HANWTITPIK (10aa)
  •    P27169    Asn-253
• IGNWSAMPSCK (11aa)
  •    P02749    Asn-253
• VLSNNSDANLELINTWVAK (19aa)
  •    P05155    Asn-253
• VVGVPYQGNATAIFIIPSEGK (21aa)
  •    P05154    Asn-262
• GSISYINVTR (10aa)
  •    P07339    Asn-263
• MIENGSISFIPTIR (14aa)
  •    P21810    Asn-270
• YIGNATAIFFIPDEGK (16aa)
  •    P01009    Asn-271
• YLGNATAIFFLPDEGK (16aa)
  •    P01009    Thr-273
• GNGTILK (7aa)
  •    Q6UXI9    Asn-273
• NETYQLFLSYSSK (13aa)
  •    P02748    Asn-277
• NAENNATFYFK (11aa)
  •    P01042    Asn-294
• INAENNATFYFK (12aa)
  •    P01042    Asn-294
• IIQVVYIHSNNITK (14aa)
  •    P21810    Asn-311
• VLNFTTK (7aa)
  •    P13671    Asn-324
• SHCIAEVENDEMPADLPSLAADFVESKDVCK (31aa)
  •    P02768    Ser-328
• LIDNNK (6aa)
  •    P07602    Asn-332
• IIDNNKTEK (9aa)
  •    P07602    Asn-332
• IAGKPTHVNVSVVMAEVDGTCY (22aa)
  •    P01876    Asn-340
• YFFNVSDEAAIIEK (14aa)
  •    P17301    Asn-343
• VGQLQLSHNLSLVILVPQNLK (21aa)
  •    P05155    Asn-352
• AGIQAFFQVQECNK (14aa)
  •    P00450    Asn-358
• IANITQGEDQYYIR (14aa)
  •    P10909    Asn-374
• GTAGNAIMDGASQIMGENR (19aa)
  •    P02675    Asn-394
• IVGGTNSSWGEWPWQVSLQVK (21aa)
  •    P03952    Asn-396
• ENITAPGSDSAVFFEQGTTR (20aa)
  •    P00450    Asn-397
• YAEDKFNETTEK (12aa)
  •    P43652    Asn-402
• NYTDCTSEGR (10aa)
  •    P02751    Asn-430
• CGIVPVIAENYNK (13aa)
  •    P02787    Asn-432
• KCGLVPVLAENYNK (14aa)
  •    P02787    Asn-432
• IYSGILNLSDITK (13aa)
  •    P03952    Asn-453
• NNVITINITGK (11aa)
  •    P16278    Asn-464
• VPGNVTAVIGETIK (14aa)
  •    P01833    Asn-469
• GFGVAIVGNYTAALPTEAALR (21aa)
  •    Q96PD5    Asn-485
• LQAPLNYTEFQK (12aa)
  •    P03952    Asn-494
• IPTQNITFQTESSVAEQEAEFQSPK (25aa)
  •    Q14624    Asn-517
• DQCIVDDITYNVNDTFHK (18aa)
  •    P02751    Asn-528
• ELHHLQEQNVSNAFLDK (17aa)
  •    P00450    Asn-762
• NVTAQICIDK (10aa)
  •    P12109    Asn-804
• ISEENETTCYMGK (13aa)
  •    P08603    Asn-911
• FDISEVNNK (9aa)
  •    P35499    Asn-1205
• NTTCQDLQIEVTVK (14aa)
  •    P0C0L4    Asn-1391
• NTTCQDLQIEVTVK (14aa)
  •    P0C0L5    Asn-1391
• NYYADNQTCDGELLFNMTK (19aa)
  •    P35555    Asn-1703
• VNQNIVYESGSINFSK (16aa)
  •    P04114    Asn-2982
• FVEGSHNSTVSITTK (15aa)
  •    P04114    Asn-3411
• FEVDSPVYNATWSASIK (17aa)
  •    P04114    Asn-3895