Hex:5 HexNAc:6 dHex:1

Taxonomy

• Homo sapiens (Human)
• Bos taurus (Bovine)
• Rattus norvegicus (Norway rat)
• Sus scrofa (Pig)

Protein

• Afamin / Homo sapiens    P43652
• Alpha-1-antitrypsin / Homo sapiens    P01009
• Alpha-2-hs-glycoprotein / Homo sapiens    P02765
• Apolipoprotein b-100 / Homo sapiens    P04114
• Apolipoprotein d / Homo sapiens    P05090
• Asporin / Homo sapiens    Q9BXN1
• Basement membrane-specific heparan sulfate proteoglycan core protein / Homo sapiens    P98160
• Beta-2-glycoprotein 1 / Homo sapiens    P02749
• Biglycan / Homo sapiens    P21810
• C-type mannose receptor 2 / Homo sapiens    Q9UBG0
• Calumenin / Homo sapiens    O43852
• Ceruloplasmin / Homo sapiens    P00450
• Collagen alpha-1(XII) chain / Homo sapiens    Q99715
• Collagen alpha-2(VI) chain / Homo sapiens    P12110
• Complement factor h / Homo sapiens    P08603
• Desmocollin-2 / Homo sapiens    Q02487
• Disintegrin and metalloproteinase domain-containing protein 15 / Homo sapiens    Q13444
• Erythropoietin / Homo sapiens    P01588
• Fibrillin-1 / Homo sapiens    P35555
• Fibrinogen beta chain / Homo sapiens    P02675
• Fibronectin / Homo sapiens    P02751
• Glandular kallikrein 1 / Homo sapiens    P06870
• Haptoglobin / Homo sapiens    P00738
• Hemopexin / Homo sapiens    P02790
• Hepatocyte growth factor receptor / Homo sapiens    P08581
• Histidine-rich glycoprotein / Homo sapiens    P04196
• Integrin alpha-L / Homo sapiens    P20701
• Kallistatin / Homo sapiens    P29622
• L-selectin / Homo sapiens    P14151
• Lysosome-associated membrane glycoprotein 2 / Homo sapiens    P13473
• Olfactomedin-like protein 3 / Homo sapiens    Q9NRN5
• Polymeric immunoglobulin receptor / Homo sapiens    P01833
• Prolactin-inducible protein / Homo sapiens    P12273
• Prosaposin / Homo sapiens    P07602
• Receptor-type tyrosine-protein phosphatase kappa / Homo sapiens    Q15262
• Serotransferrin / Homo sapiens    P02787
• Teneurin-2 / Homo sapiens    Q9NT68
• Thrombospondin-1 / Homo sapiens    P07996
• Transmembrane 9 superfamily member 3 / Homo sapiens    Q9HD45
• Uromodulin / Homo sapiens    P07911
• Platelet glycoprotein IV / Bos taurus    P26201
• Uncharacterized protein from Milk Fat Globule Membrane / Bos taurus
• Low density lipoprotein receptor-related protein 2 / Rattus norvegicus    P98158
• Mrc ox-45 surface antigen / Rattus norvegicus    P10252
• Uncharacterized protein from Undefined tissue / Rattus norvegicus
• Uncharacterized protein from Undefined tissue / Rattus norvegicus
• Uncharacterized protein from Undefined tissue / Rattus norvegicus
• Uncharacterized porcine zona pellucida glycoprotein / Sus scrofa

Source

• Kidney (UBERON_0002113)   BHK-21 (CVCL_1914)  
• Mammary Gland (UBERON_0001911)  
• Milk (UBERON_0001913)  
• Milk (UBERON_0001913)   Plasma Membrane (GO_0005886)  
• Ovary (UBERON_0000992)   CHO (CVCL_0213)  
• Umbilical Vein (UBERON_0002066)   Endothelial Cell of Umbilical Vein (CL_0002618)  
• Urine (UBERON_0001088)  
• Zona Pellucida (UBERON_0000086)  
• 3Y1-B clone 1 (CVCL_4563)  
• RPMI-1788 (CVCL_2710)   B-Lymphocyte (CL_0000236)  
• Microsome (GO_0005792)  

Reported structure

• N-Linked / Complex / Gal(?1-?)GlcNAc(?1-?)[GlcNAc(?1-?)]Man(a1-?)[Gal(?1-?)GlcNAc(?1-?)Man(a1-?)][GlcNAc(?1-4)]Man(b1-4)GlcNAc(b1-4)[Fuc(?1-6)]GlcNAc
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-2)[Gal(b1-4)GlcNAc(b1-4)]Man(a1-3)[GlcNAc(b1-2)[GlcNAc(b1-6)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-2)[Gal(b1-4)GlcNAc(b1-6)]Man(a1-6)[GalNAc(b1-4)GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-2)[Gal(b1-4)GlcNAc(b1-6)]Man(a1-?)[GalNAc(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-2)[GalNAc(b1-4)GlcNAc(b1-6)]Man(a1-?)[Gal(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-2)Man(a1-?)[GalNAc(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"+ Gal(b1-4)GlcNAc(b1-4)"
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-4)[GalNAc(b1-4)GlcNAc(b1-2)]Man(a1-3)[Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-6)[GalNAc(b1-4)GlcNAc(b1-2)]Man(a1-?)[Gal(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-?)[GlcNAc(b1-?)]Man(a1-3)[Gal(b1-4)GlcNAc(b1-?)[GlcNAc(b1-?)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / GlcNAc(b1-2)[GlcNAc(b1-4)]Man(a1-3)[GlcNAc(b1-2)[GlcNAc(b1-6)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"+ 2 x Gal(b1-4)"
• N-Linked / Complex / GlcNAc(b1-2)[GlcNAc(b1-6)]Man(a1-?)[GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"+ 2 x Gal(b1-4) + GalNAc(b1-4)"
• N-Linked / Complex / GlcNAc(b1-2)[GlcNAc(b1-?)]Man(a1-?)[GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"+ 2 x Gal(b1-4) + GlcNAc(b1-?)"

Composition

• Hex:5 HexNAc:6 dHex:1 (avg mass : 2194.0403 )

Disease

• Cancer, breast (DOID:1612)
• Prostate cancer (DOID:10283)

Reference

• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed
• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• Glycoproteomic analysis of the secretome of human endothelial cells (2013 - Yin X, Bern M, Xing Q, Ho J, Viner R, Mayr M.) / Status : Reviewed
• Automated assignments of N- and O-site specific glycosylation with extensive glycan heterogeneity of glycoprotein mixtures (2013 - Strum JS1, Nwosu CC, Hua S, Kronewitter SR, Seipert RR, Bachelor RJ, An HJ, Lebrilla CB) / Status : Reviewed
• Characterization of the N-linked oligosaccharides of megalin (gp330) from rat kidney. (2000 - Morelle W, Haslam S, Ziak M, Roth J, Morris H, Dell A) / Status : Reviewed
• Carbohydrate structures of soluble human L-selectin recombinantly expressed in baby-hamster kidney cells. (2000 - Gohlke M, Mach U, Nuck R, Zimmermann-Kordmann M, Grunow D, Fieger C, Volz B, Tauber R, Petri T, Debus N, Reutter W) / Status : Reviewed
• Unusual N-glycosylation of a recombinant human erythropoietin expressed in a human lymphoblastoid cell line does not alter its biological properties. (2000 - Cointe D, Bliard R, Jorieux S, Leroy Y, Glacet A, Verbert A, Bourel D, Chirat F) / Status : Reviewed
• Oligosaccharide analysis and molecular modeling of soluble forms of glycoproteins belonging to the Ly-6, scavenger receptor, and immunoglobulin superfamilies expressed in Chinese hamster ovary cells. (1999 - Rudd P, Wormald M, Harvey D, Devasahayam M, McAlister M, Brown M, Davis S, Barclay A, Dwek R) / Status : Reviewed
• Structural study of the sugar chains of CD36 purified from bovine mammary epithelial cells: occurrence of novel hybrid-type sugar chains containing the Neu5Ac alpha 2-->6GalNAc beta 1-->4GlcNAc and the Man alpha 1-->2Man alpha 1-->3Man alpha 1-->6Man groups. (1993 - Nakata N, Furukawa K, Greenwalt D, Sato T, Kobata A) / Status : Reviewed
• Most bovine milk fat globule membrane glycoproteins contain asparagine-linked sugar chains with GalNAc beta 1-->4GlcNAc groups. (1993 - Sato T, Furukawa K, Greenwalt D, Kobata A) / Status : Reviewed
• Structural elucidation of a variety of GalNAc-containing N-linked oligosaccharides from human urinary kallidinogenase. (1993 - Tomiya N, Awaya J, Kurono M, Hanzawa H, Shimada I, Arata Y, Yoshida T, Takahashi N) / Status : Reviewed
• Neutral oligosaccharide structures linked to asparagines of porcine zona pellucida glycoproteins. (1991 - Mori E, Takasaki S, Hedrick J, Wardrip N, Mori T, Kobata A) / Status : Reviewed
• Transfection with fragments of the adenovirus 12 gene induces tumorigenicity-associated alteration of N-linked sugar chains in rat cells. (1990 - Hiraizumi S, Takasaki S, Shiroki K, Kochibe N, Kobata A) / Status : Reviewed

Reported glycosite

• Afamin / Homo sapiens
  •        Asn-33
• Alpha-1-antitrypsin / Homo sapiens
  •        Asn-271
• Alpha-2-hs-glycoprotein / Homo sapiens
  •        Asn-156
  •        Asn-176
• Apolipoprotein b-100 / Homo sapiens
  •        Asn-3895
• Apolipoprotein d / Homo sapiens
  •        Asn-65
  •        Asn-98
• Asporin / Homo sapiens
  •        Asn-282
• Basement membrane-specific heparan sulfate proteoglycan core protein / Homo sapiens
  •        Asn-89
• Beta-2-glycoprotein 1 / Homo sapiens
  •        Asn-253
• Biglycan / Homo sapiens
  •        Asn-270
  •        Asn-311
• C-type mannose receptor 2 / Homo sapiens
  •        Asn-492
• Calumenin / Homo sapiens
  •        Asn-131
• Ceruloplasmin / Homo sapiens
  •        Asn-358
  •        Asn-397
• Collagen alpha-1(XII) chain / Homo sapiens
  •        Asn-2679
• Collagen alpha-2(VI) chain / Homo sapiens
  •        Asn-785
• Complement factor h / Homo sapiens
  •        Asn-911
• Desmocollin-2 / Homo sapiens
  •        Asn-392
• Disintegrin and metalloproteinase domain-containing protein 15 / Homo sapiens
  •        Asn-237
• Erythropoietin / Homo sapiens
  •        Asn-51
• Fibrillin-1 / Homo sapiens
  •        Asn-1581
• Fibrinogen beta chain / Homo sapiens
  •        Asn-394
• Fibronectin / Homo sapiens
  •        Asn-1236
• Glandular kallikrein 1 / Homo sapiens
  •        Undefined site
• Haptoglobin / Homo sapiens
  •        Asn-241
• Hemopexin / Homo sapiens
  •        Asn-453
• Hepatocyte growth factor receptor / Homo sapiens
  •        Asn-930
• Histidine-rich glycoprotein / Homo sapiens
  •        Asn-125
• Integrin alpha-L / Homo sapiens
  •        Asn-89
• Kallistatin / Homo sapiens
  •        Asn-157
• L-selectin / Homo sapiens
  •        Undefined site
• Lysosome-associated membrane glycoprotein 2 / Homo sapiens
  •        Asn-58
  •        Asn-275
  •        Asn-356
• Olfactomedin-like protein 3 / Homo sapiens
  •        Asn-177
  •        Asn-248
• Polymeric immunoglobulin receptor / Homo sapiens
  •        Asn-499
• Prolactin-inducible protein / Homo sapiens
  •        Asn-105
• Prosaposin / Homo sapiens
  •        Asn-332
• Receptor-type tyrosine-protein phosphatase kappa / Homo sapiens
  •        Asn-140
• Serotransferrin / Homo sapiens
  •        Asn-158
  •        Asn-432
• Teneurin-2 / Homo sapiens
  •        Asn-2197
• Thrombospondin-1 / Homo sapiens
  •        Asn-1067
• Transmembrane 9 superfamily member 3 / Homo sapiens
  •        Asn-174
• Uromodulin / Homo sapiens
  •        Asn-513
• Platelet glycoprotein IV / Bos taurus
  •        Undefined site
• Uncharacterized protein from Milk Fat Globule Membrane / Bos taurus
  •        Undefined site
• Low density lipoprotein receptor-related protein 2 / Rattus norvegicus
  •        Undefined site
• Mrc ox-45 surface antigen / Rattus norvegicus
  •        Undefined site
• Uncharacterized protein from Undefined tissue / Rattus norvegicus
  •        Undefined site
• Uncharacterized protein from Undefined tissue / Rattus norvegicus
  •        Undefined site
• Uncharacterized protein from Undefined tissue / Rattus norvegicus
  •        Undefined site
• Uncharacterized porcine zona pellucida glycoprotein / Sus scrofa
  •        Undefined site

Mass spectrometry observed peptide

• DIENFNSTQK (10aa)
  •    P43652    Asn-33
• YETTNK (6aa)
  •    P13473    Asn-58
• CIQANYSIMENGK (13aa)
  •    P05090    Asn-65
• ADGTVNQIEGEATPVNLTEPAK (22aa)
  •    P05090    Asn-98
• AIVNFTR (7aa)
  •    P98160    Asn-89
• GSNYTSK (7aa)
  •    P20701    Asn-89
• TFYWDFYTNR (10aa)
  •    P12273    Asn-105
• VIDFNCTTSSVSSAIANTK (19aa)
  •    P04196    Asn-125
• NATYGYVIDDPDPDDGFNYK (20aa)
  •    O43852    Asn-131
• NVTGFTGR (8aa)
  •    Q15262    Asn-140
• VCQDCPIIAPINDTR (15aa)
  •    P02765    Asn-156
• FINDTMAVYEAK (12aa)
  •    P29622    Asn-157
• CGLVPVLAENYNKSDNCEDTPEAGYFAVAVVKK (33aa)
  •    P02787    Asn-432
  •    VAR_058199   448:I→V   dbSNP:rs2692696
• CGLVPVLAENYNKSDNCEDTPEAGYFAVAVVKK (33aa)
  •    P02787    Asn-158
  •    VAR_058199   448:I→V   dbSNP:rs2692696
• CGLVPVLAENYNKSDNCEDTPEAGYFAVAVVK (32aa)
  •    P02787    Asn-432
  •    VAR_058199   448:I→V   dbSNP:rs2692696
• CGLVPVLAENYNKSDNCEDTPEAGYFAVAVVK (32aa)
  •    P02787    Asn-158
  •    VAR_058199   448:I→V   dbSNP:rs2692696
• AALAAFNAQNNGSNFQLEEISR (22aa)
  •    P02765    Asn-176
• IVDVNITSEGK (11aa)
  •    Q9HD45    Asn-174
• IYVIDGTQNDTAFVFPR (17aa)
  •    Q9NRN5    Asn-177
• DFQHIINR (8aa)
  •    Q13444    Asn-237
• VVIHPNYSQVDIGIIK (16aa)
  •    P00738    Asn-241
• FHLANR (6aa)
  •    Q9NRN5    Asn-248
• IGNWSAMPSCK (11aa)
  •    P02749    Asn-253
• MIENGSISFIPTIR (14aa)
  •    P21810    Asn-270
• YIGNATAIFFIPDEGK (16aa)
  •    P01009    Asn-271
• YLGNATAI (8aa)
  •    P01009    Asn-271
• LNSSTIK (7aa)
  •    P13473    Asn-275
• ITDIENGSIANIPR (14aa)
  •    Q9BXN1    Asn-282
• IIQVVYIHSNNITK (14aa)
  •    P21810    Asn-311
• LIDNNK (6aa)
  •    P07602    Asn-332
• VQPFNVTQGK (10aa)
  •    P13473    Asn-356
• AGIQAFFQVQECNK (14aa)
  •    P00450    Asn-358
• ANYTILK (7aa)
  •    Q02487    Asn-392
• GTAGNAIMDGASQIMGENR (19aa)
  •    P02675    Asn-394
• ENITAPGSDSAVFFEQGTTR (20aa)
  •    P00450    Asn-397
• CGIVPVIAENYNK (13aa)
  •    P02787    Asn-432
• AIPQPQNVTSIIGCTH (16aa)
  •    P02790    Asn-453
• WNDSPCNQSLPSICK (15aa)
  •    Q9UBG0    Asn-492
• FALLMTNCYATPSSNATDPLK (21aa)
  •    P07911    Asn-513
• NMTLFSDLVAEK (12aa)
  •    P12110    Asn-785
• ISEENETTCYMGK (13aa)
  •    P08603    Asn-911
• VVNSTTGPGEHIR (13aa)
  •    P07996    Asn-1067
• ITTTPTNGQQGNSIEEVVHADQSSCTFDNISPGIEYNVSVYTVK (44aa)
  •    P02751    Asn-1236
• AWGTPCEMCPAVNTSEYK (18aa)
  •    P35555    Asn-1581
• LGPYANTTK (9aa)
  •    Q9NT68    Asn-2197
• EAGNITTDGYEIIGK (15aa)
  •    Q99715    Asn-2679
• FEVDSPVYNATWSASIK (17aa)
  •    P04114    Asn-3895