Hex:5 HexNAc:4 dHex:3 NeuAc:1

Taxonomy

• Homo sapiens (Human)
• Mus musculus (House mouse)
• Naja kaouthia (Monocled cobra)
• Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009
• Alpha-2-HS-glycoprotein / Homo sapiens    P02765
• Alpha-2-macroglobulin / Homo sapiens    P01023
• Apolipoprotein d / Homo sapiens    P05090
• CD44 antigen / Homo sapiens    P16070
• CD59 glycoprotein / Homo sapiens    P13987
• Ceruloplasmin / Homo sapiens    P00450
• Clusterin / Homo sapiens    P10909
• Epidermal growth factor receptor / Homo sapiens    P00533
• Fibrillin-1 / Homo sapiens    P35555
• Frizzled-4 / Homo sapiens    Q9ULV1
• Immunoglobulin heavy constant mu / Homo sapiens    P01871
• Immunoglobulin j chain / Homo sapiens    P01591
• Insulin-like growth factor-binding protein complex acid labile subunit / Homo sapiens    P35858
• Interstitial collagenase / Homo sapiens    P03956
• Kallistatin / Homo sapiens    P29622
• Leukocyte-associated immunoglobulin-like receptor 1 / Homo sapiens    Q6GTX8
• Metalloproteinase inhibitor 1 / Homo sapiens    P01033
• Midasin / Homo sapiens    Q9NU22
• Neuroblastoma suppressor of tumorigenicity 1 / Homo sapiens    P41271
• Olfactomedin-4 / Homo sapiens    Q6UX06
• Phosphoinositide-3-kinase-interacting protein 1 / Homo sapiens    Q96FE7
• Plasma protease c1 inhibitor / Homo sapiens    P05155
• Plasminogen activator inhibitor 1 / Homo sapiens    P05121
• Polymeric immunoglobulin receptor / Homo sapiens    P01833
• Prostaglandin-h2 d-isomerase / Homo sapiens    P41222
• Prostate-specific antigen (psa-1) / Homo sapiens    P07288
• Prothrombin / Homo sapiens    P00734
• Receptor-type tyrosine-protein phosphatase C / Homo sapiens    P08575
• Von willebrand factor / Homo sapiens    P04275
• WAP four-disulfide core domain protein 2 / Homo sapiens    Q14508
• Complement C1q subcomponent subunit A / Mus musculus    P98086
• Immunoglobulin superfamily member 8 / Mus musculus    Q8R366
• Receptor-type tyrosine-protein phosphatase zeta / Mus musculus    B9EKR1
• Sodium/potassium-transporting ATPase subunit beta-1 / Mus musculus    P14094
• Sodium/potassium-transporting ATPase subunit beta-3 / Mus musculus    P97370
• Synaptophysin-like protein 1 / Mus musculus    O09117
• Tetraspanin-2 / Mus musculus    Q922J6
• Cobra venom factor / Naja kaouthia    Q91132
• Recombinant Spike glycoprotein (FreeStyle 293-F) - DRAFT DATA / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)    P0DTC2
• Recombinant Spike glycoprotein (HEK293) - DRAFT DATA / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)    P0DTC2

Source

• Blood Serum (UBERON_0001977)  
• Brain (UBERON_0000955)  
• Mammalian Vulva (UBERON_0000997)   A-431 (CVCL_0037)  
• Umbilical Vein (UBERON_0002066)   Endothelial Cell of Umbilical Vein (CL_0002618)  
• Urine (UBERON_0001088)  
• Venom (UBERON_0007113)  
• FreeStyle 293-F (CVCL_D603)  
• HEK293 (CVCL_0045)  
• Jurkat (CVCL_0065)  

Reported structure

• N-Linked / Complex / {Fuc(a1-3)}k[Gal(b1-4)]GlcNAc(b1-2)Man(a1-?)[{Fuc(a1-3)}j[NeuAc(a2-3)Gal(b1-4)]GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"where j+k=1.2"
• N-Linked / Complex / Structure 1851
• N-Linked / Complex / Fuc(a1-2)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-2)Man(a1-?)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-2)Man(a1-?)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc

Composition

• Hex:5 HexNAc:4 dHex:3 NeuAc:1 (avg mass : 2371.1942 )

Disease

• Carcinoma, Squamous cell (DOID:1749)
• COVID-19 (DOID:0080600)
• Prostate cancer (DOID:10283)
• T-cell childhood acute lymphocytic leukemia (DOID:0080145)

Reference

• Site-specific analysis of the SARS-CoV-2 glycan shield (2020 - Yasunori Watanabe, Joel D. Allen, Daniel Wrapp, Jason S. McLellan, Max Crispin) / Status : Unreviewed
• Deducing the N- and O- glycosylation profile of the spike protein of novel coronavirus SARS-CoV-2 (2020 - Asif Shajahan, Nitin T. Supekar, Anne S. Gleinich, Parastoo Azadi) / Status : Unreviewed
• Glycoproteomic Analysis of MGL-Binding Proteins on Acute T-Cell Leukemia Cells. (2019 - Martina Pirro, Esmee Schoof, Sandra J. van Vliet, Yoann Rombouts, Alexandre Stella, Arnoud de Ru, Yassene Mohammed, Manfred Wuhrer, Peter A. van Veelen, Paul J. Hensbergen) / Status : Reviewed
• Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis (2019 - Nicholas M. Riley, Alexander S. Hebert, Michael S. Westphall & Joshua J. Coon ) / Status : Unreviewed
• Large-scale intact glycopeptide identification by Mascot database search (2018 - Ravi Chand Bollineni, Christian Jeffrey Koehler, Randi Elin Gislefoss, Jan Haug Anonsen, Bernd Thiede) / Status : Unreviewed
• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• Glycoproteomics: Identifying the Glycosylation of Prostate Specific Antigen at Normal and High Isoelectric Points by LC-MS/MS (2014 - Song E, Mayampurath A, Yu CY, Tang H, Mechref Y) / Status : Reviewed
• Glycoproteomic analysis of the secretome of human endothelial cells (2013 - Yin X, Bern M, Xing Q, Ho J, Viner R, Mayr M.) / Status : Reviewed
• N-linked oligosaccharides of cobra venom factor contain novel alpha(1-3)galactosylated Le(x) structures. (2001 - Gowda DC, Glushka J, van-Halbeek H , Thotakura RN, Bredehorst R, Vogel C-W) / Status : Reviewed
• Characterization of the carbohydrate chains of the secreted form of the human epidermal growth factor receptor. (2000 - Stroop C, Weber W, Gerwig G, Nimtz M, Kamerling J, Vliegenthart J) / Status : Reviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens
  •        Asn-271
• Alpha-2-HS-glycoprotein / Homo sapiens
  •        Asn-156
  •        Asn-172
• Alpha-2-macroglobulin / Homo sapiens
  •        Asn-1424
• Apolipoprotein d / Homo sapiens
  •        Asn-98
• CD44 antigen / Homo sapiens
  •        Asn-57
• CD59 glycoprotein / Homo sapiens
  •        Asn-43
• Ceruloplasmin / Homo sapiens
  •        Asn-138
  •        Asn-397
• Clusterin / Homo sapiens
  •        Asn-374
• Epidermal growth factor receptor / Homo sapiens
  •        Undefined site
• Fibrillin-1 / Homo sapiens
  •        Asn-2767
• Frizzled-4 / Homo sapiens
  •        Asn-144
• Immunoglobulin heavy constant mu / Homo sapiens
  •        Asn-209
• Immunoglobulin j chain / Homo sapiens
  •        Asn-71
• Insulin-like growth factor-binding protein complex acid labile subunit / Homo sapiens
  •        Asn-554
• Interstitial collagenase / Homo sapiens
  •        Asn-143
• Kallistatin / Homo sapiens
  •        Asn-157
• Leukocyte-associated immunoglobulin-like receptor 1 / Homo sapiens
  •        Asn-69
• Metalloproteinase inhibitor 1 / Homo sapiens
  •        Asn-53
• Midasin / Homo sapiens
  •        Asn-602
• Neuroblastoma suppressor of tumorigenicity 1 / Homo sapiens
  •        Asn-39
• Olfactomedin-4 / Homo sapiens
  •        Asn-253
  •        Asn-411
• Phosphoinositide-3-kinase-interacting protein 1 / Homo sapiens
  •        Asn-66
• Plasma protease c1 inhibitor / Homo sapiens
  •        Asn-253
• Plasminogen activator inhibitor 1 / Homo sapiens
  •        Asn-288
• Polymeric immunoglobulin receptor / Homo sapiens
  •        Asn-421
  •        Asn-469
• Prostaglandin-h2 d-isomerase / Homo sapiens
  •        Asn-51
  •        Asn-78
• Prostate-specific antigen (psa-1) / Homo sapiens
  •        Asn-69
• Prothrombin / Homo sapiens
  •        Asn-121
• Receptor-type tyrosine-protein phosphatase C / Homo sapiens
  •        Asn-278
  •        Asn-421
• Von willebrand factor / Homo sapiens
  •        Asn-156
• WAP four-disulfide core domain protein 2 / Homo sapiens
  •        Asn-44
• Complement C1q subcomponent subunit A / Mus musculus
  •        Asn-146
• Immunoglobulin superfamily member 8 / Mus musculus
  •        Asn-325
• Receptor-type tyrosine-protein phosphatase zeta / Mus musculus
  •        Asn-501
• Sodium/potassium-transporting ATPase subunit beta-1 / Mus musculus
  •        Asn-193
• Sodium/potassium-transporting ATPase subunit beta-3 / Mus musculus
  •        Asn-124
• Synaptophysin-like protein 1 / Mus musculus
  •        Asn-72
• Tetraspanin-2 / Mus musculus
  •        Asn-139
• Cobra venom factor / Naja kaouthia
  •        Undefined site
• Recombinant Spike glycoprotein (FreeStyle 293-F) - DRAFT DATA / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
  •        Asn-74
  •        Asn-149
• Recombinant Spike glycoprotein (HEK293) - DRAFT DATA / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
  •        Asn-234
  •        Asn-331
  •        Asn-343

Mass spectrometry observed peptide

• TGVCPELQADQNCTQECVSDSECADNLK (28aa)
  •    Q14508    Asn-44
• NITQIVGHSGCEAK (14aa)
  •    P41271    Asn-39
• TAVNCSSDFDACLITK (16aa)
  •    P13987    Asn-43
• WFSAGLASNSSWLR (14aa)
  •    P41222    Asn-51
• FVGTPEVNQTTLYQR (15aa)
  •    P01033    Asn-53
• AFNSTLPTMAQMEK (14aa)
  •    P16070    Asn-57
• CLNWLDAQSGLASAPVSGAGNHSYCR (26aa)
  •    Q96FE7    Asn-66
• SVVAPATDGGLNLTSTFLRK (20aa)
  •    P41222    Asn-78
• SVVAPATDGGLNLTSTFLR (19aa)
  •    P41222    Asn-78
• STYNDTEDVSQASPSESEAR (20aa)
  •    Q6GTX8    Asn-69
• IIVPLNNRENISDPTSPLR (19aa)
  •    P01591    Asn-71
• VGVNKNQTVTATFGYPFR (18aa)
  •    O09117    Asn-72
• HAIHVSGTNGTKRF (14aa)
  •    P0DTC2    Asn-74
• ADGTVNQIEGEATPVNLTEPAK (22aa)
  •    P05090    Asn-98
• GHVNITRSGIECQLWR (16aa)
  •    P00734    Asn-121
• LVEDLESFLKPYSVEEQKNLTSCPDGAPFIQHGPDYR (37aa)
  •    P97370    Asn-124
• EHEGAIYPDNTTDFQR (16aa)
  •    P00450    Asn-138
• ARGNGTLITFHSAFQCCGK (19aa)
  •    Q922J6    Asn-139
• EFGFAWPESLNCSK (14aa)
  •    Q9ULV1    Asn-144
• VLTNQESPYQNHTGR (15aa)
  •    P98086    Asn-146
• YHKNNKSWMESEF (13aa)
  •    P0DTC2    Asn-149
• VCQDCPLLAPLNDTR (15aa)
  •    P02765    Asn-156
• FLNDTMAVYEAK (12aa)
  •    P29622    Asn-157
• AALAAFNAQNNGSNFQLEEISR (22aa)
  •    P02765    Asn-172
• VLGFKPKPPKNESLETYPLMMK (22aa)
  •    P14094    Asn-193
• GLTFQQNASSMCVPDQDTAIR (21aa)
  •    P01871    Asn-209
• DLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPR (59aa)
  •    P0DTC2    Asn-234
• DLPQGFSALEPLVDLPIGINITR (23aa)
  •    P0DTC2    Asn-234
• DQNTPVVHPPPTPGSCGHGGVVNISK (26aa)
  •    Q6UX06    Asn-253
• VLSNNSDANLELINTWVAK (19aa)
  •    P05155    Asn-253
• YLGNATAIFFLPDEGK (16aa)
  •    P01009    Asn-271
• NASVSISHNSCTAPDK (16aa)
  •    P08575    Asn-278
• RIGPGEPLELLCNVSGALPPPGR (23aa)
  •    Q8R366    Asn-325
• VQPTESIVRFPNITNLCPFGEVF (23aa)
  •    P0DTC2    Asn-331
• PFGEVFNATR (10aa)
  •    P0DTC2    Asn-343
• LANLTQGEDQYYLR (14aa)
  •    P10909    Asn-374
• ENLTAPGSDSAVFFEQGTTR (20aa)
  •    P00450    Asn-397
• LNDTTLQVLNTWYTK (15aa)
  •    Q6UX06    Asn-411
• LSLLEEPGNGTFTVILNQLTSR (22aa)
  •    P01833    Asn-421
• SFHNFTLCYIK (11aa)
  •    P08575    Asn-421
• VPGNVTAVLGETLK (14aa)
  •    P01833    Asn-469
• SDVPNTSPNSTSQHVAEFETER (22aa)
  •    B9EKR1    Asn-501
• DFALQNPSAVPR (12aa)
  •    P35858    Asn-554
• MAEVIGSKLNISR (13aa)
  •    Q9NU22    Asn-602
• VSNQTLSLFFTVLQDVPVR (19aa)
  •    P01023    Asn-1424
• TAIFAFNISHVSNK (14aa)
  •    P35555    Asn-2767