HexNAc:2 dHex:1

Taxonomy

• Homo sapiens (Human)
• Mus musculus (House mouse)
• Androctonus australis hector (Sahara scorpion)

Protein

• Non-secretory ribonuclease / Homo sapiens    P10153
• Uromodulin / Homo sapiens    P07911
• Prolow-density lipoprotein receptor-related protein 1 / Mus musculus    Q91ZX7
• Toxin Aah6 / Androctonus australis hector    P56743

Source

• Brain (UBERON_0000955)  
• Kidney (UBERON_0002113)  
• Liver (UBERON_0002107)  
• Milk (UBERON_0001913)  
• Spleen (UBERON_0002106)  
• Urine (UBERON_0001088)  
• Venom (UBERON_0007113)  
• Adipocytes (CL_0000136)  
• Adipose-derived stem cells (ADSCs) (CL_0000136)  

Reported structure

• N-Linked / No-core / Fuc(a1-6)[GlcNAc(b1-4)]GlcNAc
• N-Linked / No-core / GlcNAc(b1-4)[Fuc(a1-?)]GlcNAc
• N-Linked / Truncated / Structure 9700

Composition

• HexNAc:2 dHex:1 (avg mass : 570.5483 )

Disease

• Prostate cancer (DOID:10283)

Reference

• Bisecting GlcNAc Protein N-Glycosylation Is Characteristic of Human Adipogenesis. (2020 - Katherine Wongtrakul-Kish, Benjamin R Herbert, Nicolle H Packer) / Status : Reviewed
• Quantitative Longitudinal Inventory of the N-Glycoproteome of Human Milk from a Single Donor Reveals the Highly Variable Repertoire and Dynamic Site-Specific Changes (2020 - Jing Zhu, Yu-Hsien Lin, Kelly A Dingess, Marko Mank, Bernd Stahl, Albert J R Heck) / Status : Reviewed
• Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis (2019 - Nicholas M. Riley, Alexander S. Hebert, Michael S. Westphall & Joshua J. Coon ) / Status : Unreviewed
• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• Aah VI, a novel, N-glycosylated anti-insect toxin from Androctonus australis hector scorpion venom: isolation, characterisation, and glycan structure determination. (1999 - Hassani O, Loew D, Van Dorsselaer A, Papandrou M, Sorokine O, Rochat H, Sampieri F, Mansuelle P) / Status : Reviewed
• Human non-secretory ribonucleases. II. Structural characterization of the N-glycans of the kidney, liver and spleen enzymes by NMR spectroscopy and electrospray mass spectrometry. (1993 - Lawrence C, Little P, Little B, Glushka J, van Halbeek H, Alhadeff J) / Status : Reviewed

Reported glycosite

• Non-secretory ribonuclease / Homo sapiens
  •        Undefined site
• Uromodulin / Homo sapiens
  •        Asn-275
• Prolow-density lipoprotein receptor-related protein 1 / Mus musculus
  •        Asn-2128
• Toxin Aah6 / Androctonus australis hector
  •        Asn-9

Mass spectrometry observed peptide

• KDTRNESTQNCVVAEPEKM (19aa)
• ACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDCK (42aa)
  •    P07911    Asn-275     Uromodulin / Homo sapiens
• RGCKDNATDSVPLR (14aa)
  •    Q91ZX7    Asn-2128     Prolow-density lipoprotein receptor-related protein 1 / Mus musculus