GlyConnect

taxonomy (8) protein (44) source (33) structure (7) composition (1) disease (14) reference (46) site (52) peptide (8)

Taxonomy

Protein

Source

Reported structure

Composition

Hex:2 HexNAc:2 NeuAc:2 (avg mass : 1331.2059 )

Disease

Reference

Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
Site-specific analysis of the O-glycosylation of bovine fetuin by electron-transfer dissociation mass spectrometry (2014 - Windwarder M, Altmann F) / Status : Reviewed
Identification of protein O-glycosylation site and corresponding glycans using liquid chromatography-tandem mass spectrometry via mapping accurate mass and retention time shift (2014 - Huang LJ, Lin JH, Tsai JH, Chu YY, Chen YW, Chen SL, Chen SH) / Status : Reviewed
Automated assignments of N- and O-site specific glycosylation with extensive glycan heterogeneity of glycoprotein mixtures (2013 - Strum JS1, Nwosu CC, Hua S, Kronewitter SR, Seipert RR, Bachelor RJ, An HJ, Lebrilla CB) / Status : Reviewed
Recombinant MUC1 probe authentically reflects cell-specific O-glycosylation profiles of endogenous breast cancer mucin. High density and prevalent core 2-based glycosylation. (2002 - Muller S, Hanisch FG) / Status : Reviewed
In vivo glycosylation of mucin tandem repeats (2001 - Silverman, Parry, Sutton-Smith, Burdick, McDermott, Reid, Batra, Morris, Hollingsworth, Dell, Harris) / Status : Reviewed
O-glycan analysis of natural human neutrophil gelatinase B using a combination of normal phase-HPLC and online tandem mass spectrometry: implications for the domain organization of the enzyme. (2000 - Mattu T, Royle L, Langridge J, Wormald M, Van den Steen P, Van Damme J, Opdenakker G, Harvey D, Dwek R, Rudd P) / Status : Reviewed
Impaired galactosylation of core 2 O-glycans in erythrocytes of beta1,4-galactosyltransferase knockout mice. (1999 - Kotani N, Asano M, Iwakura Y, Takasaki S) / Status : Reviewed
High prevalence of 2-mono- and 2,6-di-substituted manol-terminating sequences among O-glycans released from brain glycopeptides by reductive alkaline hydrolysis. (1999 - Chai W, Yuen C, Kogelberg H, Carruthers R, Margolis R, Feizi T, Lawson A) / Status : Reviewed
Structural study of the O-linked sugar chains of human leukocyte tyrosine phosphatase CD45. (1998 - Furukawa K, Funakoshi Y, Autero M, Horejsi V, Kobata A, Gahmberg C) / Status : Reviewed
Purification and characterization of the MUC1 mucin-type glycoprotein, epitectin, from human urine: structures of the major oligosaccharide alditols. (1998 - Bhavanandan V, Zhu Q, Yamakami K, Dilulio N, Nair S, Capon C, Lemoine J, Fournet B) / Status : Reviewed
Structural determination of the O-linked sialyl oligosaccharides liberated from fetuin with endo-alpha-N-acetylgalactosaminidase-S by HPLC analysis and 600-MHz 1H-NMR spectroscopy. (1997 - Ishii-Karakasa I, Iwase H, Hotta K) / Status : Reviewed
Structures of the O-glycans on P-selectin glycoprotein ligand-1 from HL-60 cells. (1996 - Wilkins P, McEver R, Cummings R) / Status : Reviewed
Comparison of O-linked carbohydrate chains in MUC-1 mucin from normal breast epithelial cell lines and breast carcinoma cell lines. Demonstration of simpler and fewer glycan chains in tumor cells. (1996 - Lloyd KO, Burchell J, Kudryashov V, Yin BW, Taylor-Papadimitriou J) / Status : Reviewed
Sialylation and sulfation of the carbohydrate chains in respiratory mucins from a patient with cystic fibrosis. (1994 - Lo-Guidice J, Wieruszeski J, Lemoine J, Verbert A, Roussel P, Lamblin G) / Status : Reviewed
Structure determination of the disialylated poly-(N-acetyllactosamine)-containing O-linked carbohydrate chains of equine chorionic gonadotropin. (1994 - Hokke C, Roosenboom M, Thomas-Oates J, Kamerling J, Vliegenthart J) / Status : Reviewed
1H and 13C-NMR assignments for sialylated oligosaccharide-alditols related to mucins. Study of thirteen components from hen ovomucin and swallow nest mucin. (1992 - Strecker G, Wieruszeski J, Cuvillier O, Michalski J, Montreuil J) / Status : Reviewed
Oligosaccharide structures of mucins secreted by the human colonic cancer cell line CL.16E. (1992 - Capon C, Laboisse C, Wieruszeski J, Maoret J, Augeron C, Fournet B) / Status : Reviewed
The carbohydrate chains of the beta subunit of human chorionic gonadotropin produced by the choriocarcinoma cell line BeWo. Novel O-linked and novel bisecting-GlcNAc-containing N-linked carbohydrates. (1992 - Hard K, Damm J, Spruijt M, Bergwerff A, Kamerling J, Van Dedem G, Vliegenthart J) / Status : Reviewed
The effect of the carbohydrate moiety upon the size and conformation of human plasma galactoglycoprotein as judged by electron microscopy and circular dichroism. Structural studies of a glycoprotein after stepwise enzymic carbohydrate removal. (1991 - Watzlawick H, Walsh M, Ehrhard I, Slayter H, Haupt H, Schwick H, Jourdian G, Hase S, Schmid K, Brossmer R) / Status : Reviewed
Altered O-glycan synthesis in lymphocytes from patients with Wiskott-Aldrich syndrome. (1991 - Piller F, Le Deist F, Weinberg K, Parkman R, Fukuda M) / Status : Reviewed
Structures of acidic O-linked polylactosaminoglycans on human skim milk mucins. (1990 - Hanisch F, Peter-Katalinic J, Egge H, Dabrowski U, Uhlenbruck G) / Status : Reviewed
Structure determination of the major N- and O-linked carbohydrate chains of the beta subunit from equine chorionic gonadotropin. (1990 - Damm J, Hard K, Kamerling J, van Dedem G, Vliegenthart J) / Status : Reviewed
Isolation and structural characterization of sialic-acid-containing glycopeptides of the O-glycosidic type from the urine of two patients with an hereditary deficiency in alpha-N-acetylgalactosaminidase activity. (1989 - Linden H, Klein R, Egge H, Peter-Katalinic J, Dabrowski J, Schindler D) / Status : Reviewed
Structural analysis of O-glycosidic type of sialyloligosaccharide-alditols derived from urinary glycopeptides of a sialidosis patient. (1988 - van Pelt J, Van Bilsen D, Kamerling J, Vliegenthart J) / Status : Reviewed
Structural studies on oncofetal carbohydrate antigens (Ca 19-9, Ca 50, and Ca 125) carried by O-linked sialyloligosaccharides on human amniotic mucins. (1988 - Hanisch F, Uhlenbruck G, Peter-Katalinic J, Egge H) / Status : Reviewed
Human T-lymphocyte activation is associated with changes in O-glycan biosynthesis. (1988 - Piller F, Piller V, Fox R, Fukuda M) / Status : Reviewed
Structural analysis by fast-atom-bombardment mass spectrometry of the mixture of alditols derived from the O-linked oligosaccharides of murine glycophorins. (1988 - Krotkiewski H, Lisowska E, Angel A, Nilsson B) / Status : Reviewed
Identification of a tetrasialylated monofucosylated tetraantennary N-linked carbohydrate chain in human platelet glycocalicin. (1988 - Korrel S, Clemetson K, van Halbeek H, Kamerling J, Sixma J, Vliegenthart J) / Status : Reviewed
Comparative study of the mucin-type sugar chains of human chorionic gonadotropin present in the urine of patients with trophoblastic diseases and healthy pregnant women. (1988 - Amano J, Nishimura R, Mochizuki M, Kobata A) / Status : Reviewed
Structures of the sialylated oligosaccharide chains in swine tracheal mucin glycoproteins. (1987 - Rana SS, Chandrasekaran EV, Mendicino J) / Status : Reviewed
The structures of N- and O-glycosidic carbohydrate chains of a chondroitin sulfate proteoglycan isolated from the media of the human aorta. (1987 - Akiyama F, Stevens R, Hayashi S, Swann D, Binette J, Caterson B, Schmid K, Van Halbeek H, Mutsaers J, Gerwig G) / Status : Reviewed
Presence of an O-glycosidically linked hexasaccharide in fetuin. (1987 - Edge A, Spiro R) / Status : Reviewed
Structures of O-linked oligosaccharides isolated from normal granulocytes, chronic myelogenous leukemia cells, and acute myelogenous leukemia cells. (1986 - Fukuda M, Carlsson S, Klock J, Dell A) / Status : Reviewed
Characterization of O-glycosidically linked oligosaccharides of rat erythrocyte membrane sialoglycoproteins. (1986 - Edge A, Van Langenhove A, Reinhold V, Weber P) / Status : Reviewed
The structure of the O-glycosidic oligosaccharide chains of the major Zajdela hepatoma ascites-cell-membrane glycoprotein. (1986 - Nato F, Goulut C, Bourrillon R, Van Halbeek H, Vliegenthart J) / Status : Reviewed
Structural variations of O-linked oligosaccharides present in leukosialin isolated from erythroid, myeloid, and T-lymphoid cell lines. (1986 - Carlsson S, Sasaki H, Fukuda M) / Status : Reviewed
Structures of O-linked oligosaccharides present in the proteoglycans secreted by human mammary epithelial cells. (1986 - Gowda D, Bhavanandan V, Davidson E) / Status : Reviewed
The structure of the carbohydrate units of human plasma galactoglycoprotein determined by 500-megahertz 1H NMR spectroscopy. (1984 - Akiyama K, Simons E, Bernasconi P, Schmid K, van Halbeek H, Vliegenthart J, Haupt H, Schwick H) / Status : Reviewed
Structural studies on the O-linked carbohydrate chains of human platelet glycocalicin. (1984 - Korrel S, Clemetson K, Van Halbeek H, Kamerling J, Sixma J, Vliegenthart J) / Status : Reviewed
Structures of the O-linked oligosaccharides of the major cell surface sialoglycoprotein of MAT-B1 and MAT-C1 ascites sublines of the 13762 rat mammary adenocarcinoma. (1984 - Hull S, Laine R, Kaizu T, Rodriguez I, Carraway K) / Status : Reviewed
The carbohydrate moiety of human platelet glycocalicin. (1983 - Tsuji T, Tsunehisa S, Watanabe Y, Yamamoto K, Tohyama H, Osawa T) / Status : Reviewed
Structure of O-glycosidically linked sugar units from plasma membranes of an ascites hepatoma, AH 66. (1982 - Funakoshi I, Yamashina I) / Status : Reviewed
Structures of N-linked and O-linked oligosaccharides on proteoglycan monomer isolated from the Swarm rat chondrosarcoma. (1982 - Nilsson B, De Luca S, Lohmander S, Hascall V) / Status : Reviewed
Oligosaccharides on proteoglycans from the swarm rat chondrosarcoma. (1980 - Lohmander L, De Luca S, Nilsson B, Hascall V, Caputo C, Kimura J, Heinegard D) / Status : Reviewed
Chemical structure of epiglycanin, the major glycoprotein of the TA3-Ha ascites cell. The carbohydrate chains. (1979 - van den Eijnden D, Evans N, Codington J, Reinhold V, Silber C, Jeanloz R) / Status : Reviewed

Reported glycosite

Chondroitin sulfate proteoglycan / Homo sapiens
- Undefined site
Choriogonadotropin - alpha and beta chains / Homo sapiens
- Undefined site
Choriogonadotropin beta chain / Homo sapiens
- Undefined site
Coagulation factor IX / Homo sapiens
- Thr-85
- Thr-205
- Thr-215
Glycocalicin / Homo sapiens
- Undefined site
Insulin-like growth factor II / Homo sapiens
- Thr-99
Inter-alpha-trypsin inhibitor heavy chain h4 / Homo sapiens
- Thr-725
Leukosialin (cd43) / Homo sapiens
- Undefined site
Matrix metalloproteinase-9 / Homo sapiens
- Undefined site
Muc1 fusion protein / Homo sapiens
- Undefined site
Mucin / Homo sapiens
- Undefined site
Mucin-1 / Homo sapiens
- Undefined site
P-selectin glycoprotein ligand (psgl-1) / Homo sapiens
- Undefined site
Plasma protease c1 inhibitor / Homo sapiens
- Thr-47
Proheparin-binding EGF-like growth factor / Homo sapiens
- Thr-37
Prostaglandin-h2 d-isomerase / Homo sapiens
- Ser-67
- Ser-81
Protein heg homolog 1 / Homo sapiens
- Thr-91
Protein yipf3 / Homo sapiens
- Thr-346
- Ser-349
Proteoglycan / Homo sapiens
- Undefined site
Receptor-type tyrosine-protein phosphatase C / Homo sapiens
- Undefined site
Recombinant Mucin-1 Muc1f (delta tr) / Homo sapiens
- Undefined site
Recombinant Mucin-1 Muc1f/2tr / Homo sapiens
- Undefined site
Recombinant Mucin-1 Muc1f/5actr / Homo sapiens
- Undefined site
Recombinant Mucin-1 Muc1f/5btr / Homo sapiens
- Undefined site
Uncharacterized protein from Granulocyte / Homo sapiens
- Undefined site
Uncharacterized protein from Granulocyte / Homo sapiens
- Undefined site
Uncharacterized protein from Urine / Homo sapiens
- Undefined site
Urine glycopeptide / Homo sapiens
- Undefined site
Alpha-2-hs-glycoprotein / Bos taurus
- Undefined site
- Ser-271
- Thr-280
- Ser-296
Kappa casein / Bos taurus
- Thr-152
- Thr-163
Choriogonadotropin beta chain / Equus caballus
- Undefined site
Epiglycanin / Mus musculus
- Undefined site
Glycophorin / Mus musculus
- Undefined site
Uncharacterized protein from Erythrocyte Membrane / Mus musculus
- Undefined site
Uncharacterized protein from Erythrocyte Membrane / Mus musculus
- Undefined site
Uncharacterized protein from Erythrocyte Membrane / Mus musculus
- Undefined site
Brain non dialyzable glycopeptide / Oryctolagus cuniculus
- Undefined site
Asgp-1 / Rattus norvegicus
- Undefined site
Major membrane glycoprotein - MII2 / Rattus norvegicus
- Undefined site
Sialoglycoprotein (rspg-4) / Rattus norvegicus
- Undefined site
Uncharacterized protein from Cell Membranes / Rattus norvegicus
- Undefined site
Uncharacterized proteoglycan / Rattus norvegicus
- Undefined site
Mucin / Sus scrofa
- Undefined site
Mucin / Collocalia sp
- Undefined site

Mass spectrometry observed peptide

GLAAGTSNPDPPTVSTDQLLPLGGGR (26aa)
- Q99075 Thr-37
GLAAGTSNPDPPTVSTDQLLPLGGGRDR (28aa)
- Q99075 Thr-37
VATTVISK (8aa)
- P05155 Thr-47
SVVAPATDGGLNLTSTFLRKNQCETR (26aa)
- P41222 Ser-81
SVVAPATDGGLNLTSTFLRKNQCETR (26aa)
- P41222 Ser-67
APEPGAATQR (10aa)
- Q9ULI3 Thr-91
DVSTPPTVLPDNFPR (15aa)
- P01344 Thr-99
AVAVTLQSH (9aa)
- Q9GZM5 Thr-346
AVAVTLQSH (9aa)
- Q9GZM5 Ser-349
IEETTMTTQTPAPIQAPSAILPLPGQSVER (30aa)
- Q14624 Thr-725

- Hex:2 HexNAc:2 NeuAc:2 / O-Linked (avg mass : 1331.2059)