Hex:6 HexNAc:6 dHex:3 NeuAc:3

Taxonomy

• Homo sapiens (Human)
• Ovis aries (Sheep)
• Gallus gallus (Chicken)

Protein

• Amyloid beta a4 protein / Homo sapiens    P05067
• Angiotensin-converting enzyme / Homo sapiens    P12821
• Cadherin-2 / Homo sapiens    P19022
• CD109 antigen / Homo sapiens    Q6YHK3
• Coagulation factor XII / Homo sapiens    P00748
• Ecto-ADP-ribosyltransferase 4 / Homo sapiens    Q93070
• G-protein coupled receptor 126 / Homo sapiens    Q86SQ4
• Galectin-3-binding protein / Homo sapiens    Q08380
• Multimerin-2 / Homo sapiens    Q9H8L6
• Peroxidasin homolog / Homo sapiens    Q92626
• Phosphatidylinositol-glycan-specific phospholipase D / Homo sapiens    P80108
• Plasma protease c1 inhibitor / Homo sapiens    P05155
• Seizure 6-like protein 2 / Homo sapiens    Q6UXD5
• Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 / Homo sapiens    Q4LDE5
• Target of Nesh-SH3 / Homo sapiens    Q7Z7G0
• Major prion protein (VRQ/VRQ polymorphism) 21K slow variant / Ovis aries    Q712V9
• Major prion protein (VRQ/VRQ polymorphism) CH1641 variant / Ovis aries    Q712V9

Source

• Blood Serum (UBERON_0001977)  
• Brain (UBERON_0000955)  
• Colon (UBERON_0001155)  
• Prefrontal Cortex (UBERON:0000451)  
• C6 (CVCL_0194)   Glial Cell (CL_0000125)  

Reported structure

• N-Linked / Complex / Fuc(a1-2)[NeuAc(a2-6)]Gal(b1-4)GlcNAc(b1-2)[Fuc(a1-2)[NeuAc(a2-6)]Gal(b1-4)GlcNAc(b1-6)]Man(a1-3)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)][GlcNAc(b1-4)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Structure 9977
• N-Linked / Complex / Structure 11233
• N-Linked / Complex / Structure 11249
• N-Linked / Complex / Structure 11612
• N-Linked / Complex / Structure 11641

Composition

• Hex:6 HexNAc:6 dHex:3 NeuAc:3 (avg mass : 3522.2424 )

Disease

• Prostate cancer (DOID:10283)
• Scrapie (DOID:5434)
• Tumor, Glial (DOID:3070)

Reference

• Site-specific analysis of N-glycans from different sheep prion strains (2021 - Natali Nakić ,Thanh Hoa Tran ,Mislav Novokmet,Olivier Andreoletti,Gordan Lauc,Giuseppe Legname) / Status : Reviewed
• Toward robust N-glycomics of various tissue samples that may contain glycans with unknown or unexpected structures. (2021 - Suzuki N, Abe T, Hanzawa K, Natsuka S) / Status : Reviewed
• Spatial and temporal diversity of glycome expression in mammalian brain (2020 - Lee J, Ha S, Kim M, Kim SW, Yun J, Ozcan S, Hwang H, Ji IJ, Yin D, Webster MJ, Shannon Weickert C, Kim JH, Yoo JS, Grimm R, Bahn S, Shin HS, An HJ) / Status : Reviewed
• Large-scale intact glycopeptide identification by Mascot database search (2018 - Ravi Chand Bollineni, Christian Jeffrey Koehler, Randi Elin Gislefoss, Jan Haug Anonsen, Bernd Thiede) / Status : Unreviewed
• N-linked oligosaccharide of beta-amyloid precursor protein (beta APP) of C6 glioma cells: putative regulatory role in beta APP processing. (1995 - Saito F, Tani A, Miyatake T, Yanagisawa K) / Status : Reviewed

Reported glycosite

• Amyloid beta a4 protein / Homo sapiens
  •        Undefined site
• Angiotensin-converting enzyme / Homo sapiens
  •        Asn-714
• Cadherin-2 / Homo sapiens
  •        Asn-651
• CD109 antigen / Homo sapiens
  •        Asn-337
• Coagulation factor XII / Homo sapiens
  •        Asn-433
• Ecto-ADP-ribosyltransferase 4 / Homo sapiens
  •        Asn-178
• G-protein coupled receptor 126 / Homo sapiens
  •        Asn-667
• Galectin-3-binding protein / Homo sapiens
  •        Asn-551
• Multimerin-2 / Homo sapiens
  •        Asn-261
  •        Asn-379
• Peroxidasin homolog / Homo sapiens
  •        Asn-964
• Phosphatidylinositol-glycan-specific phospholipase D / Homo sapiens
  •        Asn-321
  •        Asn-568
• Plasma protease c1 inhibitor / Homo sapiens
  •        Asn-238
• Seizure 6-like protein 2 / Homo sapiens
  •        Asn-247
• Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 / Homo sapiens
  •        Asn-2779
• Target of Nesh-SH3 / Homo sapiens
  •        Asn-690
• Major prion protein (VRQ/VRQ polymorphism) 21K slow variant / Ovis aries
  •        Asn-200
• Major prion protein (VRQ/VRQ polymorphism) CH1641 variant / Ovis aries
  •        Asn-200

Mass spectrometry observed peptide

• DSIMENGTLCYEVHYR (16aa)
  •    Q93070    Asn-178     Ecto-ADP-ribosyltransferase 4 / Homo sapiens
• GENFTETDIK (10aa)
  •    Q712V9    Asn-200     Major prion protein (VRQ/VRQ polymorphism) 21K slow variant / Ovis aries
  •    Q712V9    Asn-200     Major prion protein (VRQ/VRQ polymorphism) CH1641 variant / Ovis aries
• DTFVNASR (8aa)
  •    P05155    Asn-238     Plasma protease c1 inhibitor / Homo sapiens
• LLANSSMLGEGQVLR (15aa)
  •    Q6UXD5    Asn-247     Seizure 6-like protein 2 / Homo sapiens
• NLSLDVEANR (10aa)
  •    Q9H8L6    Asn-261     Multimerin-2 / Homo sapiens
• NINYTER (7aa)
  •    P80108    Asn-321     Phosphatidylinositol-glycan-specific phospholipase D / Homo sapiens
• NVSTNVFFK (9aa)
  •    Q6YHK3    Asn-337     CD109 antigen / Homo sapiens
• NLSELHMTTAR (11aa)
  •    Q9H8L6    Asn-379     Multimerin-2 / Homo sapiens
• NHSCEPCQTLAVR (13aa)
  •    P00748    Asn-433     Coagulation factor XII / Homo sapiens
• AAIPSALDTNSSK (13aa)
  •    Q08380    Asn-551     Galectin-3-binding protein / Homo sapiens
• LNVEAANWTVR (11aa)
  •    P80108    Asn-568     Phosphatidylinositol-glycan-specific phospholipase D / Homo sapiens
• NWTITR (6aa)
  •    P19022    Asn-651     Cadherin-2 / Homo sapiens
• IDLNSTSHVNITTR (14aa)
  •    Q86SQ4    Asn-667     G-protein coupled receptor 126 / Homo sapiens
• NVSVDSTHPTK (11aa)
  •    Q7Z7G0    Asn-690     Target of Nesh-SH3 / Homo sapiens
• FDVNQLQNTTIK (12aa)
  •    P12821    Asn-714     Angiotensin-converting enzyme / Homo sapiens
• DENESPIPCFLAGDHR (16aa)
  •    Q92626    Asn-964     Peroxidasin homolog / Homo sapiens
• KPNPVMNGSIK (11aa)
  •    Q4LDE5    Asn-2779     Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 / Homo sapiens