Hex:6 HexNAc:6 dHex:3 NeuAc:3

Taxonomy

• Homo sapiens (Human)
• Ovis aries (Sheep)

Protein

• Amyloid beta a4 protein / Homo sapiens    P05067
• Angiotensin-converting enzyme / Homo sapiens    P12821
• Cadherin-2 / Homo sapiens    P19022
• CD109 antigen / Homo sapiens    Q6YHK3
• Coagulation factor XII / Homo sapiens    P00748
• Ecto-ADP-ribosyltransferase 4 / Homo sapiens    Q93070
• G-protein coupled receptor 126 / Homo sapiens    Q86SQ4
• Galectin-3-binding protein / Homo sapiens    Q08380
• Multimerin-2 / Homo sapiens    Q9H8L6
• Peroxidasin homolog / Homo sapiens    Q92626
• Phosphatidylinositol-glycan-specific phospholipase D / Homo sapiens    P80108
• Plasma protease c1 inhibitor / Homo sapiens    P05155
• Seizure 6-like protein 2 / Homo sapiens    Q6UXD5
• Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 / Homo sapiens    Q4LDE5
• Target of Nesh-SH3 / Homo sapiens    Q7Z7G0
• Major prion protein (VRQ/VRQ polymorphism) 21K slow variant / Ovis aries    Q712V9
• Major prion protein (VRQ/VRQ polymorphism) CH1641 variant / Ovis aries    Q712V9

Source

• Blood Serum (UBERON_0001977)  
• Brain (UBERON_0000955)  
• C6 (CVCL_0194)   Glial Cell (CL_0000125)  

Reported structure

• N-Linked / Complex / Fuc(a1-2)[NeuAc(a2-6)]Gal(b1-4)GlcNAc(b1-2)[Fuc(a1-2)[NeuAc(a2-6)]Gal(b1-4)GlcNAc(b1-6)]Man(a1-3)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)][GlcNAc(b1-4)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Structure 9977

Composition

• Hex:6 HexNAc:6 dHex:3 NeuAc:3 (avg mass : 3522.2424 )

Disease

• Prostate cancer (DOID:10283)
• Scrapie (DOID:5434)
• Tumor, Glial (DOID:3070)

Reference

• Site-specific analysis of N-glycans from different sheep prion strains (2021 - Natali Nakić ,Thanh Hoa Tran ,Mislav Novokmet,Olivier Andreoletti,Gordan Lauc,Giuseppe Legname) / Status : Reviewed
• Large-scale intact glycopeptide identification by Mascot database search (2018 - Ravi Chand Bollineni, Christian Jeffrey Koehler, Randi Elin Gislefoss, Jan Haug Anonsen, Bernd Thiede) / Status : Unreviewed
• N-linked oligosaccharide of beta-amyloid precursor protein (beta APP) of C6 glioma cells: putative regulatory role in beta APP processing. (1995 - Saito F, Tani A, Miyatake T, Yanagisawa K) / Status : Reviewed

Reported glycosite

• Amyloid beta a4 protein / Homo sapiens
  •        Undefined site
• Angiotensin-converting enzyme / Homo sapiens
  •        Asn-714
• Cadherin-2 / Homo sapiens
  •        Asn-651
• CD109 antigen / Homo sapiens
  •        Asn-337
• Coagulation factor XII / Homo sapiens
  •        Asn-433
• Ecto-ADP-ribosyltransferase 4 / Homo sapiens
  •        Asn-178
• G-protein coupled receptor 126 / Homo sapiens
  •        Asn-667
• Galectin-3-binding protein / Homo sapiens
  •        Asn-551
• Multimerin-2 / Homo sapiens
  •        Asn-261
  •        Asn-379
• Peroxidasin homolog / Homo sapiens
  •        Asn-964
• Phosphatidylinositol-glycan-specific phospholipase D / Homo sapiens
  •        Asn-321
  •        Asn-568
• Plasma protease c1 inhibitor / Homo sapiens
  •        Asn-238
• Seizure 6-like protein 2 / Homo sapiens
  •        Asn-247
• Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 / Homo sapiens
  •        Asn-2779
• Target of Nesh-SH3 / Homo sapiens
  •        Asn-690
• Major prion protein (VRQ/VRQ polymorphism) 21K slow variant / Ovis aries
  •        Asn-200
• Major prion protein (VRQ/VRQ polymorphism) CH1641 variant / Ovis aries
  •        Asn-200

Mass spectrometry observed peptide

• DSIMENGTLCYEVHYR (16aa)
  •    Q93070    Asn-178     Ecto-ADP-ribosyltransferase 4 / Homo sapiens
• GENFTETDIK (10aa)
  •    Q712V9    Asn-200     Major prion protein (VRQ/VRQ polymorphism) 21K slow variant / Ovis aries
  •    Q712V9    Asn-200     Major prion protein (VRQ/VRQ polymorphism) CH1641 variant / Ovis aries
• DTFVNASR (8aa)
  •    P05155    Asn-238     Plasma protease c1 inhibitor / Homo sapiens
• LLANSSMLGEGQVLR (15aa)
  •    Q6UXD5    Asn-247     Seizure 6-like protein 2 / Homo sapiens
• NLSLDVEANR (10aa)
  •    Q9H8L6    Asn-261     Multimerin-2 / Homo sapiens
• NINYTER (7aa)
  •    P80108    Asn-321     Phosphatidylinositol-glycan-specific phospholipase D / Homo sapiens
• NVSTNVFFK (9aa)
  •    Q6YHK3    Asn-337     CD109 antigen / Homo sapiens
• NLSELHMTTAR (11aa)
  •    Q9H8L6    Asn-379     Multimerin-2 / Homo sapiens
• NHSCEPCQTLAVR (13aa)
  •    P00748    Asn-433     Coagulation factor XII / Homo sapiens
• AAIPSALDTNSSK (13aa)
  •    Q08380    Asn-551     Galectin-3-binding protein / Homo sapiens
• LNVEAANWTVR (11aa)
  •    P80108    Asn-568     Phosphatidylinositol-glycan-specific phospholipase D / Homo sapiens
• NWTITR (6aa)
  •    P19022    Asn-651     Cadherin-2 / Homo sapiens
• IDLNSTSHVNITTR (14aa)
  •    Q86SQ4    Asn-667     G-protein coupled receptor 126 / Homo sapiens
• NVSVDSTHPTK (11aa)
  •    Q7Z7G0    Asn-690     Target of Nesh-SH3 / Homo sapiens
• FDVNQLQNTTIK (12aa)
  •    P12821    Asn-714     Angiotensin-converting enzyme / Homo sapiens
• DENESPIPCFLAGDHR (16aa)
  •    Q92626    Asn-964     Peroxidasin homolog / Homo sapiens
• KPNPVMNGSIK (11aa)
  •    Q4LDE5    Asn-2779     Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 / Homo sapiens