Hex:2 HexNAc:2 NeuGc:1

Taxonomy

• Homo sapiens (Human)
• Mus musculus (House mouse)
• Rattus norvegicus (Norway rat)
• Sus scrofa (Pig)
• Salvelinus leucomaenis pluvius (Whitespotted char)
• Rana ridibunda (Laughing frog)

Protein

• Zona pellucida sperm-binding protein 3 / Homo sapiens    P21754
• Zona pellucida sperm-binding protein matrix / Mus musculus    P20239    Q62005    P10761
• Mucin-2 glycopeptide a / Rattus norvegicus    Q62635
• Mucin-2 glycopeptide b / Rattus norvegicus    Q62635
• Uncharacterized porcine zona pellucida glycoprotein / Sus scrofa    
• Polysialoglycoprotein (psgp) / Salvelinus leucomaenis pluvius    
• Mucin / Rana ridibunda    

Source

• Small Intestine (UBERON_0002108)  
• Zona Pellucida (UBERON_0000086)  
• Egg Cell  
• Egg Cell   Jelly Coat  

Reported structure

• O-Linked / Core 1 / Gal(?1-4)GlcNAc(?1-6)[Gal(?1-3)]GalNAc+"+ NeuGc(?2-3)"
• O-Linked / Core 1 / Gal(a1-4)GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-3)GalNAc
• O-Linked / Core 1 / Gal(b1-4)GlcNAc(b1-3)Gal(b1-3)[NeuGc(a2-6)]GalNAc
• O-Linked / Core 1 / GalNAc(b1-3)Gal(b1-4)Gal(b1-3)[NeuGc(a2-6)]GalNAc
• O-Linked / Core 1 / NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-3)GalNAc
• O-Linked / Core 2 / Gal(b1-4)GlcNAc(b1-6)[NeuGc(a2-3)Gal(b1-3)]GalNAc
• O-Linked / Core 2 / NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-6)[Gal(b1-3)]GalNAc
• O-Linked / Undefined core / Gal(?1-?)GlcNAc(?1-6)[NeuGc(?2-?)Gal(?1-3)]GalNAc

Composition

• Hex:2 HexNAc:2 NeuGc:1 (avg mass : 1055.9474 )

Disease

Reference

• Murine and human zona pellucida 3 derived from mouse eggs express identical O-glycans. (2003 - Dell A, Chalabi S, Easton RL, Haslam SM, Sutton-Smith M, Patankar MS, Lattanzio F, Panico M, Morris HR, Clark GF) / Status : Reviewed
• Diversity of O-linked glycosylation patterns between species. Characterization of 25 carbohydrate chains from oviducal mucins of Rana ridibunda. (2001 - Mourad R, Morelle W, Neveu A, Strecker G) / Status : Reviewed
• Structural analysis of murine zona pellucida glycans. Evidence for the expression of core 2-type O-glycans and the Sd(a) antigen. (2000 - Easton RL, Patankar MS, Lattanzio FA, Leaven TH, Morris HR, Clark GF, Dell A) / Status : Reviewed
• Structure of the O-linked carbohydrate chains of porcine zona pellucida glycoproteins. (1994 - Hokke C, Damm J, Penninkhof B, Aitken R, Kamerling J, Vliegenthart J) / Status : Reviewed
• Characterization of two different glycosylated domains from the insoluble mucin complex of rat small intestine. (1993 - Carlstedt I, Herrmann A, Karlsson H, Sheehan J, Fransson L, Hansson G) / Status : Reviewed
• Structures of the carbohydrate units of polysialoglycoproteins isolated from the eggs of four species of salmonid fishes. (1985 - Iwasaki M, Inoue S) / Status : Reviewed

Reported glycosite

• Zona pellucida sperm-binding protein 3 / Homo sapiens
  •        Undefined site
• Zona pellucida sperm-binding protein matrix / Mus musculus
  •        Undefined site
• Mucin-2 glycopeptide a / Rattus norvegicus
  •        Undefined site
• Mucin-2 glycopeptide b / Rattus norvegicus
  •        Undefined site
• Uncharacterized porcine zona pellucida glycoprotein / Sus scrofa
  •        Undefined site
• Polysialoglycoprotein (psgp) / Salvelinus leucomaenis pluvius
  •        Undefined site
• Mucin / Rana ridibunda
  •        Undefined site

Mass spectrometry observed peptide