Hex:4 HexNAc:4 NeuGc:1

Taxonomy

• Homo sapiens (Human)
• Bos taurus (Bovine)

Protein

• CD59 glycoprotein / Homo sapiens    P13987
• Sparc / Homo sapiens    P09486
• Uromodulin / Homo sapiens    P07911
• Mucin / Bos taurus    

Source

• Umbilical Vein (UBERON_0002066)   Endothelial Cell of Umbilical Vein (CL_0002618)  
• Urine (UBERON_0001088)  
• Erythrocyte (CL_0000232)   Plasma Membrane (GO_0005886)  

Reported structure

• O-Linked / Undefined core / NeuGc(?2-3)Gal(?1-?)GlcNAc(?1-?)[Gal(?1-?)GlcNAc(?1-?)]Gal(?1-?)GlcNAc(?1-?)Gal(?1-?)GalNAc

Composition

• Hex:4 HexNAc:4 NeuGc:1 (avg mass : 1786.6222 )

Disease

• Prostate cancer (DOID:10283)

Reference

• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• Glycoproteomic analysis of the secretome of human endothelial cells (2013 - Yin X, Bern M, Xing Q, Ho J, Viner R, Mayr M.) / Status : Reviewed
• Interaction of bovine erythrocyte N-glycolylneuraminic acid-containing gangliosides and glycoproteins with a human Hanganutziu-Deicher serum. (1986 - Nowak JA, Jain NK, Stinson MW, Merrick JM) / Status : Reviewed

Reported glycosite

• CD59 glycoprotein / Homo sapiens
  •        Asn-43
• Sparc / Homo sapiens
  •        Asn-116
• Uromodulin / Homo sapiens
  •        Asn-275
  •        Asn-513
• Mucin / Bos taurus
  •        Undefined site

Mass spectrometry observed peptide

• TAVNCSSDFDACLITK (16aa)
  •    P13987    Asn-43     CD59 glycoprotein / Homo sapiens
• ACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDCK (42aa)
  •    P07911    Asn-275     Uromodulin / Homo sapiens
• FALLMTNCYATPSSNATDPLK (21aa)
  •    P07911    Asn-513     Uromodulin / Homo sapiens