Hex:7 HexNAc:7 dHex:3 NeuAc:1

Taxonomy

• Homo sapiens (Human)
• Ovis aries (Sheep)

Protein

• Carcinoembryonic antigen-related cell adhesion molecule 5 / Homo sapiens    P06731
• Major prion protein (VRQ/VRQ polymorphism) 21K slow variant / Ovis aries    Q712V9
• Major prion protein (VRQ/VRQ polymorphism) CH1641 variant / Ovis aries    Q712V9

Source

• Brain (UBERON_0000955)  
• Colon (UBERON_0001155)  
• Prefrontal Cortex (UBERON:0000451)  
• LS174T (CVCL_1384)  

Reported structure

• N-Linked / Complex / Structure 9948
• N-Linked / Complex / Structure 11599

Composition

• Hex:7 HexNAc:7 dHex:3 NeuAc:1 (avg mass : 3305.064 )

Disease

• Colon adenocarcinoma (DOID:234)
• Scrapie (DOID:5434)

Reference

• Carcinoembryonic antigen glycosylation (2021 - Kolarich D) / Status : Reviewed
• Site-specific analysis of N-glycans from different sheep prion strains (2021 - Natali Nakić ,Thanh Hoa Tran ,Mislav Novokmet,Olivier Andreoletti,Gordan Lauc,Giuseppe Legname) / Status : Reviewed
• Spatial and temporal diversity of glycome expression in mammalian brain (2020 - Lee J, Ha S, Kim M, Kim SW, Yun J, Ozcan S, Hwang H, Ji IJ, Yin D, Webster MJ, Shannon Weickert C, Kim JH, Yoo JS, Grimm R, Bahn S, Shin HS, An HJ) / Status : Reviewed

Reported glycosite

• Carcinoembryonic antigen-related cell adhesion molecule 5 / Homo sapiens
  •        Undefined site
  •        Asn-288
• Major prion protein (VRQ/VRQ polymorphism) 21K slow variant / Ovis aries
  •        Asn-200
• Major prion protein (VRQ/VRQ polymorphism) CH1641 variant / Ovis aries
  •        Asn-200

Mass spectrometry observed peptide

• GENFTETDIK (10aa)
  •    Q712V9    Asn-200     Major prion protein (VRQ/VRQ polymorphism) CH1641 variant / Ovis aries
  •    Q712V9    Asn-200     Major prion protein (VRQ/VRQ polymorphism) 21K slow variant / Ovis aries
• IPNIT (5aa)
  •    P06731    Asn-288     Carcinoembryonic antigen-related cell adhesion molecule 5 / Homo sapiens