Hex:6 HexNAc:6 dHex:2 NeuAc:1

Taxonomy

• Homo sapiens (Human)
• Mus musculus (House mouse)
• Ovis aries (Sheep)

Protein

• Carcinoembryonic antigen-related cell adhesion molecule 5 / Homo sapiens    P06731
• Glutamate receptor 2 / Mus musculus    P23819
• Major prion protein (VRQ/VRQ polymorphism) 21K slow variant / Ovis aries    Q712V9
• Major prion protein (VRQ/VRQ polymorphism) CH1641 variant / Ovis aries    Q712V9

Source

• Ascitic fluid (UBERON_0007795)  
• Brain (UBERON_0000955)  
• Colon (UBERON_0001155)  
• Liver (UBERON_0002107)  
• LS174T (CVCL_1384)  

Reported structure

• N-Linked / Complex / Structure 9980
• N-Linked / Complex / Structure 10462

Composition

• Hex:6 HexNAc:6 dHex:2 NeuAc:1 (avg mass : 2793.5836 )

Disease

• Colon adenocarcinoma (DOID:234)
• Scrapie (DOID:5434)

Reference

• Carcinoembryonic antigen glycosylation (2021 - Kolarich D) / Status : Reviewed
• Site-specific analysis of N-glycans from different sheep prion strains (2021 - Natali Nakić ,Thanh Hoa Tran ,Mislav Novokmet,Olivier Andreoletti,Gordan Lauc,Giuseppe Legname) / Status : Reviewed
• Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis (2019 - Nicholas M. Riley, Alexander S. Hebert, Michael S. Westphall & Joshua J. Coon ) / Status : Unreviewed

Reported glycosite

• Carcinoembryonic antigen-related cell adhesion molecule 5 / Homo sapiens
  •        Undefined site
  •        Asn-104
  •        Asn-182
  •        Asn-360
• Glutamate receptor 2 / Mus musculus
  •        Asn-406
• Major prion protein (VRQ/VRQ polymorphism) 21K slow variant / Ovis aries
  •        Asn-200
• Major prion protein (VRQ/VRQ polymorphism) CH1641 variant / Ovis aries
  •        Asn-200

Mass spectrometry observed peptide

• YPNAS (5aa)
  •    P06731    Asn-104     Carcinoembryonic antigen-related cell adhesion molecule 5 / Homo sapiens
• NQSLP (5aa)
  •    P06731    Asn-360     Carcinoembryonic antigen-related cell adhesion molecule 5 / Homo sapiens
  •    P06731    Asn-182     Carcinoembryonic antigen-related cell adhesion molecule 5 / Homo sapiens
• GENFTETDIK (10aa)
  •    Q712V9    Asn-200     Major prion protein (VRQ/VRQ polymorphism) CH1641 variant / Ovis aries
  •    Q712V9    Asn-200     Major prion protein (VRQ/VRQ polymorphism) 21K slow variant / Ovis aries
• MVVTLTELPSGNDTSGLENK (20aa)
  •    P23819    Asn-406     Glutamate receptor 2 / Mus musculus