Hex:6 HexNAc:6 dHex:2 NeuAc:1

Taxonomy

• Homo sapiens (Human)
• Mus musculus (House mouse)
• Ovis aries (Sheep)

Protein

• Carcinoembryonic antigen-related cell adhesion molecule 5 / Homo sapiens    P06731
• Glutamate receptor 2 / Mus musculus    P23819
• Major prion protein (VRQ/VRQ polymorphism) 21K slow variant / Ovis aries    Q712V9
• Major prion protein (VRQ/VRQ polymorphism) CH1641 variant / Ovis aries    Q712V9

Source

• Ascitic fluid (UBERON_0007795)  
• Brain (UBERON_0000955)  
• Cerebellum (UBERON_0002037)  
• Colon (UBERON_0001155)  
• Frontal Cortex (UBERON_0001870)  
• Hippocampul formation (UBERON:0002421)  
• Liver (UBERON_0002107)  
• Prefrontal Cortex (UBERON:0000451)  
• Striatum (UBERON_0002345)  
• LS174T (CVCL_1384)  

Reported structure

• N-Linked / Complex / Structure 9980
• N-Linked / Complex / Structure 10462
• N-Linked / Complex / Structure 11650
• N-Linked / Complex / Structure 11807
• N-Linked / Complex / Structure 11855

Composition

• Hex:6 HexNAc:6 dHex:2 NeuAc:1 (avg mass : 2793.5836 )

Disease

• Colon adenocarcinoma (DOID:234)
• Scrapie (DOID:5434)

Reference

• Mammalian brain glycoproteins exhibit diminished glycan complexity compared to other tissues (2022 - Williams SE, Noel M, Lehoux S, Cetinbas M, Xavier RJ, Sadreyev RI, Scolnick EM, Smoller JW, Cummings RD, Mealer RG) / Status : Reviewed
• Carcinoembryonic antigen glycosylation (2021 - Kolarich D) / Status : Reviewed
• Site-specific analysis of N-glycans from different sheep prion strains (2021 - Natali Nakić ,Thanh Hoa Tran ,Mislav Novokmet,Olivier Andreoletti,Gordan Lauc,Giuseppe Legname) / Status : Reviewed
• Spatial and temporal diversity of glycome expression in mammalian brain (2020 - Lee J, Ha S, Kim M, Kim SW, Yun J, Ozcan S, Hwang H, Ji IJ, Yin D, Webster MJ, Shannon Weickert C, Kim JH, Yoo JS, Grimm R, Bahn S, Shin HS, An HJ) / Status : Reviewed
• Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis (2019 - Nicholas M. Riley, Alexander S. Hebert, Michael S. Westphall & Joshua J. Coon ) / Status : Unreviewed

Reported glycosite

• Carcinoembryonic antigen-related cell adhesion molecule 5 / Homo sapiens
  •        Undefined site
  •        Asn-104
  •        Asn-182
  •        Asn-360
• Glutamate receptor 2 / Mus musculus
  •        Asn-406
• Major prion protein (VRQ/VRQ polymorphism) 21K slow variant / Ovis aries
  •        Asn-200
• Major prion protein (VRQ/VRQ polymorphism) CH1641 variant / Ovis aries
  •        Asn-200

Mass spectrometry observed peptide

• YPNAS (5aa)
  •    P06731    Asn-104     Carcinoembryonic antigen-related cell adhesion molecule 5 / Homo sapiens
• NQSLP (5aa)
  •    P06731    Asn-360     Carcinoembryonic antigen-related cell adhesion molecule 5 / Homo sapiens
  •    P06731    Asn-182     Carcinoembryonic antigen-related cell adhesion molecule 5 / Homo sapiens
• GENFTETDIK (10aa)
  •    Q712V9    Asn-200     Major prion protein (VRQ/VRQ polymorphism) CH1641 variant / Ovis aries
  •    Q712V9    Asn-200     Major prion protein (VRQ/VRQ polymorphism) 21K slow variant / Ovis aries
• MVVTLTELPSGNDTSGLENK (20aa)
  •    P23819    Asn-406     Glutamate receptor 2 / Mus musculus