Hex:4 HexNAc:5 NeuAc:1 NeuGc:1

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009
• Alpha-2-HS-glycoprotein / Homo sapiens    P02765
• CD27 antigen / Homo sapiens    P26842
• Hemopexin / Homo sapiens    P02790
• Immunoglobulin heavy constant alpha 2 / Homo sapiens    P01877
• Prostaglandin-h2 d-isomerase / Homo sapiens    P41222
• Protein AMBP / Homo sapiens    P02760
• Prothrombin / Homo sapiens    P00734
• Serotransferrin / Homo sapiens    P02787
• Uromodulin / Homo sapiens    P07911
• WAP four-disulfide core domain protein 2 / Homo sapiens    Q14508

Source

• Urine (UBERON_0001088)  

Reported structure

Composition

• Hex:4 HexNAc:5 NeuAc:1 NeuGc:1 (avg mass : 2281.0751 )

Disease

• Prostate cancer (DOID:10283)

Reference

• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens
  •        Asn-271
• Alpha-2-HS-glycoprotein / Homo sapiens
  •        Asn-156
  •        Asn-176
• CD27 antigen / Homo sapiens
  •        Asn-95
• Hemopexin / Homo sapiens
  •        Asn-64
• Immunoglobulin heavy constant alpha 2 / Homo sapiens
  •        Asn-205
• Prostaglandin-h2 d-isomerase / Homo sapiens
  •        Asn-78
• Protein AMBP / Homo sapiens
  •        Asn-250
• Prothrombin / Homo sapiens
  •        Asn-143
• Serotransferrin / Homo sapiens
  •        Asn-432
• Uromodulin / Homo sapiens
  •        Asn-322
  •        Asn-513
• WAP four-disulfide core domain protein 2 / Homo sapiens
  •        Asn-44

Mass spectrometry observed peptide

• TGVCPELQADQNCTQECVSDSECADNLK (28aa)
  •    Q14508    Asn-44
• CSDGWSFDATTLDDNGTMLFFK (22aa)
  •    P02790    Asn-64
• SVVAPATDGGLNLTSTFLR (19aa)
  •    P41222    Asn-78
• NCTITANAECACR (13aa)
  •    P26842    Asn-95
• YPHKPEINSTTHPGADLQENFCR (23aa)
  •    P00734    Asn-143
• VCQDCPLLAPLNDTR (15aa)
  •    P02765    Asn-156
• AALAAFNAQNNGSNFQLEEISR (22aa)
  •    P02765    Asn-176
• TPLTANITK (9aa)
  •    P01877    Asn-205
• YFYNGTSMACETFQYGGCMGNGNNFVTEK (29aa)
  •    P02760    Asn-250
• YLGNATAIFFLPDEGK (16aa)
  •    P01009    Asn-271
• WHCQCKQDFNITDISLLEHR (20aa)
  •    P07911    Asn-322
• CGLVPVLAENYNK (13aa)
  •    P02787    Asn-432
• FALLMTNCYATPSSNATDPLK (21aa)
  •    P07911    Asn-513