GlyConnect

taxonomy (1) protein (2) source (1) structure (9) composition (7) disease (1) reference (2) site (2) peptide (0)

Taxonomy

Homo sapiens (Human)

Protein

Muc1 fusion protein / Homo sapiens
Mucin-1 / Homo sapiens P15941

Source

Mammary Gland (UBERON_0001911) T-47D (CVCL_0553)

Reported structure

Composition

Disease

Cancer, breast (DOID:1612)

Reference

Recombinant MUC1 probe authentically reflects cell-specific O-glycosylation profiles of endogenous breast cancer mucin. High density and prevalent core 2-based glycosylation. (2002 - Muller S, Hanisch FG) / Status : Reviewed
Comparison of O-linked carbohydrate chains in MUC-1 mucin from normal breast epithelial cell lines and breast carcinoma cell lines. Demonstration of simpler and fewer glycan chains in tumor cells. (1996 - Lloyd KO, Burchell J, Kudryashov V, Yin BW, Taylor-Papadimitriou J) / Status : Reviewed

Reported glycosite

Muc1 fusion protein / Homo sapiens
- Undefined site
Mucin-1 / Homo sapiens
- Undefined site

Mass spectrometry observed peptide

- O-Linked / Core 0 (avg mass : 221.2103)
- O-Linked / Core 0 (avg mass : 512.4682)
- O-Linked / Core 1 (avg mass : 383.3527)
- O-Linked / Core 1 (avg mass : 674.6106)
- O-Linked / Core 1 (avg mass : 674.6106)
- O-Linked / Core 1 (avg mass : 965.8685)
- O-Linked / Core 2 (avg mass : 1039.948)
- O-Linked / Core 2 (avg mass : 1039.948)
- O-Linked / Core 2 (avg mass : 1331.2059)