Cell line CCRF-CEM

Taxonomy

• Homo sapiens (Human)

Protein

• Gpl115 / Homo sapiens
• Receptor-type tyrosine-protein phosphatase C / Homo sapiens    P08575

Source

• CCRF-CEM (CVCL_0207)   Lymphocyte (CL_0000542)  
• CCRF-CEM (CVCL_0207)   T-Lymphocyte (CL_0000084)  

Reported structure

• O-Linked / Core 0 / GalNAc
• O-Linked / Core 1 / Gal(b1-3)GalNAc
• O-Linked / Core 1 / Gal(b1-3)GalNAc+"+ NeuAc"
• O-Linked / Core 1 / NeuAc(a2-3)Gal(b1-3)GalNAc
• O-Linked / Core 1 / Gal(b1-3)GalNAc+"+ 2 x NeuAc"

Composition

• HexNAc:1 (avg mass : 221.2103 )
• Hex:1 HexNAc:1 (avg mass : 383.3527 )
• Hex:1 HexNAc:1 NeuAc:1 (avg mass : 674.6106 )
• Hex:1 HexNAc:1 NeuAc:2 (avg mass : 965.8685 )

Disease

• Leukemia, Acute lymphoblastic (DOID:9952)
• Leukemia, Acute lymphoblastic and HIV-1

Reference

• Altered sialylation of CD45 in HIV-1-infected T lymphocytes. (1994 - Lefebvre J, Giordanengo V, Doglio A, Cagnon L, Breittmayer J, Peyron J, Lesimple J) / Status : Reviewed
• Characterization of a human lymphocyte surface sialoglycoprotein that is defective in Wiskott-Aldrich syndrome. (1984 - Remold-O'Donnell E, Kenney D, Parkman R, Cairns L, Savage B, Rosen F) / Status : Reviewed

Reported glycosite

• Gpl115 / Homo sapiens
  •        Undefined site
• Receptor-type tyrosine-protein phosphatase C / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide