Cytoplasm

Taxonomy

• Mus musculus (House mouse)
• Dictyostelium discoideum (Slime mold)
• Leishmania major

Protein

• Glycoprotein fp21 / Dictyostelium discoideum    P52285
• Gp96/92 / Leishmania major

Source

• Liver (UBERON_0002107)   Cytoplasm (GO_0005737)  
• Cytoplasm (GO_0005737)  

Reported structure

• N-Linked/O-Linked / Truncated If N-Linked / GlcNAc
• N-Linked / No-core / Man(a1-3)Man(b1-4)GlcNAc
• N-Linked / No-core / Man(a1-6)Man(b1-4)GlcNAc
• N-Linked / No-core / Man(a1-3)[Man(a1-6)]Man(b1-4)GlcNAc
• N-Linked / No-core / Man(a1-6)Man(b1-4)GlcNAc(b1-4)GlcNAc
• O-Linked / No-core / Gal(a1-6)Gal(a1-?)Fuc(a1-2)Gal(b1-3)GlcNAc
• N-Linked / High-Mannose / Man(a1-2)Man(a1-3)[Man(a1-6)]Man(b1-4)GlcNAc
• N-Linked / No-core / Man(a1-3)[Man(a1-6)]Man(a1-6)Man(b1-4)GlcNAc
• N-Linked / No-core / Man(a1-6)Man(a1-6)Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / High-Mannose / Man(a1-2)Man(a1-2)Man(a1-3)[Man(a1-6)]Man(b1-4)GlcNAc
• N-Linked / High-Mannose / Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-3)]Man(b1-4)GlcNAc
• N-Linked / No-core / Man(a1-3)[Man(a1-6)]Man(a1-6)Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / High-Mannose / Glc(a1-3)Man(a1-2)Man(a1-2)Man(a1-3)[Man(a1-6)]Man(b1-4)GlcNAc
• N-Linked / High-Mannose / Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-3)]Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / High-Mannose / Glc(a1-3)Man(a1-2)Man(a1-2)Man(a1-3)[Man(a1-?)Man(b1-6)]Man(b1-4)GlcNAc
• N-Linked / High-Mannose / Glc(a1-3)Man(a1-2)Man(a1-2)Man(a1-3)[Man(a1-?)Man(b1-6)]Man(b1-4)GlcNAc+"+ Man"
• N-Linked / High-Mannose / Man(a1-2)Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-2)Man(a1-2)Man(a1-3)]Man(b1-4)GlcNAc
• N-Linked / High-Mannose / Man(a1-2)Man(a1-6)[Man(a1-3)]Man(a1-6)[Man(a1-2)Man(a1-2)Man(a1-3)]Man(b1-4)GlcNAc
• N-Linked / High-Mannose / Man(a1-2)Man(a1-3)[Man(a1-2)Man(a1-6)]Man(a1-6)[Man(a1-2)Man(a1-2)Man(a1-3)]Man(b1-4)GlcNAc
• N-Linked / High-Mannose / Glc(a1-3)Man(a1-2)Man(a1-2)Man(a1-3)[Man(a1-2)Man(a1-3)[Man(a1-2)Man(b1-6)]Man(a1-6)]Man(b1-4)GlcNAc
• N-Linked / Complex / NeuAc(a2-6)GlcNAc(b1-2)Man(a1-3)[NeuAc(a2-6)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc

Composition

• HexNAc:1 (avg mass : 221.2103 )
• Hex:2 HexNAc:1 (avg mass : 545.4951 )
• Hex:2 HexNAc:2 (avg mass : 748.6901 )
• Hex:3 HexNAc:1 (avg mass : 707.6375 )
• Hex:3 HexNAc:1 dHex:1 (avg mass : 853.7805 )
• Hex:3 HexNAc:2 (avg mass : 910.8325 )
• Hex:3 HexNAc:4 NeuAc:2 (avg mass : 1899.7383 )
• Hex:4 HexNAc:1 (avg mass : 869.7799 )
• Hex:4 HexNAc:2 (avg mass : 1072.9749 )
• Hex:5 HexNAc:1 (avg mass : 1031.9223 )
• Hex:5 HexNAc:2 (avg mass : 1235.1173 )
• Hex:6 HexNAc:1 (avg mass : 1194.0647 )
• Hex:7 HexNAc:1 (avg mass : 1356.2071 )
• Hex:8 HexNAc:1 (avg mass : 1518.3495 )
• Hex:9 HexNAc:1 (avg mass : 1680.4919 )
• Hex:10 HexNAc:1 (avg mass : 1842.6343 )

Disease

Reference

• Quantitation and isomeric structure analysis of free oligosaccharides present in the cytosol fraction of mouse liver: detection of a free disialobiantennary oligosaccharide and glucosylated oligomannosides. (1999 - Ohashi S, Iwai K, Mega T, Hase S) / Status : Reviewed
• The cytoplasmic F-box binding protein SKP1 contains a novel pentasaccharide linked to hydroxyproline in Dictyostelium. (1998 - Teng-umnuay P, Morris H, Dell A, Panico M, Paxton T, West C) / Status : Reviewed
• Identification, characterisation and genomic cloning of a O-linked N-acetylglucosamine-containing cytoplasmic Leishmania glycoprotein. (1993 - Handman E, Barnett L, Osborn A, Goding J, Murray P) / Status : Reviewed

Reported glycosite

• Glycoprotein fp21 / Dictyostelium discoideum
  •        Hyp-143
• Gp96/92 / Leishmania major
  •        Undefined site

Mass spectrometry observed peptide